There are 3 ways to get from Los Osos to San Diego by bus, plane, train (Amtrak), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus, fly
best- Take the bus from 10th & Los Osos Valley to Government Center
- Fly from San Luis Obispo County Regional Airport (SBP) to San Diego International Airport (SAN)SBP - SAN
4h 52m$55–350Train (Amtrak)
- Take the train from San Luis Obispo to San DiegoPacific Surfliner
9h 9m$103–170Drive 315.2 mi
- Drive from Los Osos to San Diego315.2 mi
5h 39m$58–84
San Luis Obispo County Regional Airport (SBP) to San Diego International Airport (SAN) flights
Questions & Answers
The cheapest way to get from Los Osos to San Diego is to drive which costs $55 - $85 and takes 5h 39m.
The fastest way to get from Los Osos to San Diego is to bus and fly which takes 4h 52m and costs $55 - $350.
The distance between Los Osos and San Diego is 296 miles. The road distance is 317 miles.
The best way to get from Los Osos to San Diego without a car is to train which takes 9h 9m and costs $100 - $170.
It takes approximately 4h 52m to get from Los Osos to San Diego, including transfers.
Yes, the driving distance between Los Osos to San Diego is 317 miles. It takes approximately 5h 39m to drive from Los Osos to San Diego.
There are 1964+ hotels available in San Diego.
What companies run services between Los Osos, CA, USA and San Diego, CA, USA?
Amtrak operates a train from San Luis Obispo to San Diego twice daily. Tickets cost $60–120 and the journey takes 8h 52m.
Transport is disrupted due to the Russia-Ukraine war. Read more
- Website
- alaskaair.com
Flights from San Luis Obispo County Regional Airport to San Diego International Airport
- Ave. Duration
- 1h 19m
- When
- Every day
- Estimated price
- $50–340
- Website
- united.com
Flights from San Luis Obispo County Regional Airport to San Diego International Airport via Los Angeles
- Ave. Duration
- 3h 17m
- When
- Every day
- Estimated price
- $50–340
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from San Luis Obispo to San Diego
- Ave. Duration
- 8h 52m
- Frequency
- Twice daily
- Estimated price
- $60–120
- Website
- https://www.amtrak.com/home.html
- Website
- slorta.org
Bus from 10th & Los Osos Valley to Government Center
- Ave. Duration
- 54 min
- Frequency
- Hourly
- Estimated price
- $2–3
- Website
- https://www.slorta.org
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