There are 5 ways to get from Los Angeles to Otay Mesa by bus, train, night bus, car, plane or tram

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  3 h 57 min

  1. Take the bus from Los Angeles, Ca to San Ysidro, Ca 9465

$23 - $50

Cheapest option

Night bus  •  4 h 3 min

  1. Take the night bus from Los Angeles Union Station Amtrak to San Diego Santa Fe Depot Amtrak Amtrak Thruway Connecting Service

$4 - $6

3 alternative options

Train  •  4 h 11 min

  1. Take the train from Los Angeles Union Station Amtrak to San Diego Santa Fe Depot Amtrak Pacific Surfliner

$38 - $80

Drive  •  2 h 21 min

  1. Drive from Los Angeles to Otay Mesa 135.9 miles

$13 - $20

Fly, tram, line 905 bus  •  4 h 3 min

  1. Fly from Los Angeles (LAX) to San Diego (SAN) LAX - SAN
  2. Take the tram from America Plaza Station to Iris Ave Station
  3. Take the line 905 bus from Iris Avenue Transit Center to Otay Mesa Rd & Heritage Rd

$113 - $357

Questions & Answers

The cheapest way to get from Los Angeles to Otay Mesa is to night bus which costs $4 - $6 and takes 4 h 3 min.

More details

The quickest way to get from Los Angeles to Otay Mesa is to drive which costs $13 - $20 and takes 2 h 21 min.

More details

The distance between Los Angeles and Otay Mesa is 126 miles. The road distance is 135.9 miles.

Get driving directions

It takes approximately 3 h 57 min to get from Los Angeles to Otay Mesa, including transfers.

More details

No, there is no direct bus from Los Angeles to Otay Mesa. However, there are services departing from Los Angeles, Ca and arriving at Otay Mesa Rd & Heritage Rd via E San Ysidro Blvd & San Ysidro Transit Center and Iris Avenue Transit Center. The journey, including transfers, takes approximately 3 h 57 min.

More details

What companies run services between Los Angeles, CA, USA and Otay Mesa, CA, USA?

Greyhound USA operates a bus from Los Angeles to Otay Mesa hourly. Tickets cost $19 - $45 and the journey takes 2 h 55 min. Alternatively, Amtrak operates a train from Los Angeles to Otay Mesa every 2 hours. Tickets cost $30 - $75 and the journey takes 2 h 53 min.

Airlines
American Airlines
Website
aa.com
Flights from Los Angeles to San Diego
Ave. Duration
52 min
When
Every day
Estimated price
$110 - $600
United Airlines
Website
united.com
Flights from Los Angeles to San Diego
Ave. Duration
57 min
When
Every day
Estimated price
$110 - $650
Delta
Website
delta.com
Flights from Los Angeles to San Diego
Ave. Duration
59 min
When
Every day
Estimated price
$140 - $600
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Los Angeles Union Station Amtrak to San Diego Santa Fe Depot Amtrak
Ave. Duration
2 h 53 min
Frequency
Every 2 hours
Estimated price
$30 - $75
Website
amtrak.com
Coach Seat
$30 - $50
Flexi Coach Seat
$55 - $85
Business Coach Seat
$50 - $75
Room
$170 - $240
San Diego Metro Transit
Phone
+1 619-233-3004
Website
sdmts.com
Tram from America Plaza Station to Iris Ave Station
Ave. Duration
38 min
Frequency
Every 15 minutes
Estimated price
$3
Schedules at
sdmts.com
Bus operators

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