There are 8 ways to get from Los Angeles to Great Smoky Mountains by plane, car, train or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly from Los Angeles, drive  •  9 h 49 min

  1. Fly from Los Angeles (LAX) to Knoxville (TYS) LAX - TYS
  2. Drive from Knoxville to Great Smoky Mountains

$275 - $480

Cheapest option

Bus, Megabus, drive  •  2 days 7 h

  1. Take the bus from Los Angeles, Ca to Dallas, Tx
  2. Take the bus from Dallas, Tx to Atlanta, Ga
  3. Take the Megabus from Atlanta GA to Knoxville
  4. Drive from Mountain Grove SB before Majestic Grove to Great Smoky Mountains

$242 - $577

6 alternative options

Fly from Burbank, drive  •  11 h 39 min

  1. Fly from Burbank (BUR) to Knoxville (TYS) BUR - TYS
  2. Drive from Knoxville to Great Smoky Mountains

$283 - $1,119

Train to Santa Ana, fly, drive  •  11 h 9 min

  1. Take the train from Los Angeles Union Station Amtrak to Santa Ana Regional Transportation Center Amtrak
  2. Fly from Santa Ana (SNA) to Knoxville (TYS) SNA - TYS
  3. Drive from Knoxville to Great Smoky Mountains

$291 - $1,055

Train, bus, Megabus, drive via Clinton & Jackson  •  2 days 13 h

  1. Take the train from Los Angeles Union Station Amtrak to Chicago Union Station Amtrak
  2. Take the bus from Chicago to Chattanooga
  3. Take the Megabus from Chattanooga to Knoxville
  4. Drive from Knoxville to Great Smoky Mountains

$351 - $923

Train, bus, Megabus, drive  •  2 days 14 h

  1. Take the train from Los Angeles Union Station Amtrak to New Orleans Union Passenger Terminal Amtrak
  2. Take the bus from New Orleans to Marta Civic Center Station - Nb
  3. Take the Megabus from Atlanta GA to Knoxville
  4. Drive from Mountain Grove SB before Majestic Grove to Great Smoky Mountains

$312 - $837

Train, bus, drive  •  3 days 1 h

  1. Take the train from Los Angeles Union Station Amtrak to New Orleans Union Passenger Terminal Amtrak
  2. Take the train from New Orleans Union Passenger Terminal Amtrak to Greensboro Galyon Transportation Center Amtrak
  3. Take the bus from Greensboro, Nc to Winston Salem, Nc
  4. Take the bus from Winston Salem, Nc to Asheville, Nc
  5. Drive from Asheville, Nc to Great Smoky Mountains

$394 - $1,154

Drive  •  35 h 55 min

  1. Drive from Los Angeles to Great Smoky Mountains 2258.1 miles

$220 - $320

What companies run services between Los Angeles, CA, USA and Great Smoky Mountains, TN, USA?

There is no direct connection from Los Angeles to Great Smoky Mountains. However, you can take the bus to LAX Terminal 3 Upper Level FlyAway Stop, take the walk to Los Angeles airport, fly to Knoxville, then take the drive to Great Smoky Mountains. Alternatively, you can take the train to Burbank-Bob Hope Airport station, take the walk to Burbank airport, fly to Knoxville, then take the drive to Great Smoky Mountains.

Airlines
United Airlines
Website
united.com
Flights from Los Angeles to Knoxville via Chicago O'Hare
Ave. Duration
7 h 2 min
When
Every day
Estimated price
$440 - $700
Flights from Los Angeles to Knoxville via Houston
Ave. Duration
6 h 55 min
When
Every day
Estimated price
$440 - $700
Flights from Los Angeles to Knoxville via Washington Dulles
Ave. Duration
7 h 50 min
When
Every day
Estimated price
$440 - $700
Flights from Burbank to Knoxville via Denver, Chicago O'Hare
Ave. Duration
9 h 57 min
When
Saturday
Estimated price
$280 - $1,200
Flights from Burbank to Knoxville via San Francisco, Washington Dulles
Ave. Duration
10 h 28 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$340 - $1,400
Flights from Burbank to Knoxville via San Francisco, Houston
Ave. Duration
11 h 25 min
When
Every day
Estimated price
$310 - $1,300
Flights from Burbank to Knoxville via San Francisco, Chicago O'Hare
Ave. Duration
11 h 30 min
When
Every day
Estimated price
$310 - $1,300
Flights from Burbank to Knoxville via Denver, Houston
Ave. Duration
12 h 20 min
When
Every day
Estimated price
$300 - $1,200
Flights from Santa Ana to Knoxville via Houston
Ave. Duration
7 h 3 min
When
Every day
Estimated price
$270 - $1,100
Flights from Santa Ana to Knoxville via Chicago O'Hare
Ave. Duration
6 h 59 min
When
Every day
Estimated price
$270 - $1,200
Flights from Santa Ana to Knoxville via Newark
Ave. Duration
10 h 27 min
When
Monday, Tuesday, Wednesday, Thursday and Sunday
Estimated price
$330 - $1,300
Delta
Website
delta.com
Flights from Los Angeles to Knoxville via Atlanta
Ave. Duration
6 h 49 min
When
Every day
Estimated price
$500 - $800
Flights from Los Angeles to Knoxville via Minneapolis
Ave. Duration
7 h 4 min
When
Monday, Thursday, Friday, Saturday and Sunday
Estimated price
$500 - $800
Flights from Los Angeles to Knoxville via Detroit
Ave. Duration
7 h 3 min
When
Every day
Estimated price
$500 - $800
Flights from Burbank to Knoxville via Salt Lake City, Atlanta
Ave. Duration
8 h 41 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,100
Flights from Burbank to Knoxville via Salt Lake City, Minneapolis
Ave. Duration
10 h 21 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,100
Flights from Santa Ana to Knoxville via Atlanta
Ave. Duration
7 h 12 min
When
Every day
Estimated price
$250 - $1,100
Flights from Santa Ana to Knoxville via Detroit
Ave. Duration
6 h 58 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,100
Flights from Santa Ana to Knoxville via Minneapolis
Ave. Duration
6 h 59 min
When
Saturday
Estimated price
$260 - $1,100
American Airlines
Website
aa.com
Flights from Los Angeles to Knoxville via Dallas/Ft.Worth
Ave. Duration
6 h 18 min
When
Every day
Estimated price
$450 - $750
Flights from Los Angeles to Knoxville via Charlotte
Ave. Duration
7 h 7 min
When
Every day
Estimated price
$450 - $750
Flights from Los Angeles to Knoxville via Chicago O'Hare
Ave. Duration
6 h 59 min
When
Every day
Estimated price
$450 - $750
Flights from Burbank to Knoxville via Phoenix, Dallas/Ft.Worth
Ave. Duration
8 h 7 min
When
Every day
Estimated price
$270 - $1,100
Flights from Burbank to Knoxville via Phoenix, Charlotte
Ave. Duration
9 h 9 min
When
Every day
Estimated price
$290 - $1,100
Flights from Burbank to Knoxville via Phoenix, Chicago O'Hare
Ave. Duration
11 h 35 min
When
Every day
Estimated price
$290 - $1,100
Flights from Santa Ana to Knoxville via Dallas/Ft.Worth
Ave. Duration
6 h 26 min
When
Every day
Estimated price
$260 - $1,000
Flights from Santa Ana to Knoxville via Chicago O'Hare
Ave. Duration
9 h 13 min
When
Every day
Estimated price
$280 - $1,100
Flights from Santa Ana to Knoxville via Phoenix, Dallas/Ft.Worth
Ave. Duration
7 h 47 min
When
Every day
Estimated price
$260 - $1,000
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Los Angeles Union Station Amtrak to Santa Ana Regional Transportation Center Amtrak
Ave. Duration
46 min
Frequency
Every 2 hours
Estimated price
$22 - $45
Website
amtrak.com
Coach Seat
$22 - $35
Flexi Coach Seat
$40 - $60
Business Coach Seat
$29 - $45
Room
$130 - $190
Train from Los Angeles Union Station Amtrak to Chicago Union Station Amtrak
Ave. Duration
43 h 5 min
Frequency
Twice daily
Estimated price
$270 - $850
Website
amtrak.com
Coach Seat
$270 - $410
Flexi Coach Seat
$480 - $700
Business Coach Seat
$550 - $850
Room
$1,000 - $1,500
Train from Los Angeles Union Station Amtrak to New Orleans Union Passenger Terminal Amtrak
Ave. Duration
45 h 40 min
Frequency
6 times a week
Estimated price
$240 - $750
Website
amtrak.com
Coach Seat
$240 - $360
Flexi Coach Seat
$440 - $650
Business Coach Seat
$500 - $750
Room
$900 - $1,300
Train from New Orleans Union Passenger Terminal Amtrak to Greensboro Galyon Transportation Center Amtrak
Ave. Duration
19 h 37 min
Frequency
Once daily
Estimated price
$110 - $340
Website
amtrak.com
Coach Seat
$110 - $180
Flexi Coach Seat
$210 - $300
Business Coach Seat
$240 - $340
Room
$470 - $650
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Los Angeles, Ca to Dallas, Tx
Ave. Duration
29 h 20 min
Frequency
Hourly
Estimated price
$130 - $340
Website
greyhound.com
Economy
$130 - $220
Flexible
$250 - $340
Bus from Dallas, Tx to Atlanta, Ga
Ave. Duration
17 h 30 min
Frequency
Hourly
Estimated price
$80 - $200
Website
greyhound.com
Economy
$80 - $130
Flexible
$150 - $200
Bus from Greensboro, Nc to Winston Salem, Nc
Ave. Duration
45 min
Frequency
Hourly
Estimated price
$9 - $20
Website
greyhound.com
Economy
$9 - $14
Flexible
$16 - $20
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2 h 55 min
Frequency
Every 2 hours
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Atlanta GA to Knoxville
Ave. Duration
4 h 5 min
Frequency
Twice daily
Estimated price
$22 - $35
Schedules at
us.megabus.com
Bus from Chicago to Chattanooga
Ave. Duration
12 h 14 min
Frequency
Twice daily
Estimated price
$55 - $70
Schedules at
us.megabus.com
Bus from Chattanooga to Knoxville
Ave. Duration
2 h
Frequency
Twice daily
Estimated price
$12 - $22
Schedules at
us.megabus.com
Bus from New Orleans to Marta Civic Center Station - Nb
Ave. Duration
8 h 45 min
Frequency
4 times a day
Estimated price
$35 - $60
Schedules at
us.megabus.com

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Questions & Answers

How far is it from Los Angeles to Great Smoky Mountains?

The distance between Los Angeles and Great Smoky Mountains is 3159 km. The road distance is 3613 km.

What is the cheapest way to get from Los Angeles to Great Smoky Mountains?

The cheapest way to get from Los Angeles to Great Smoky Mountains is to drive which costs $220 - $320 and takes 35 h 55 min.

What is the fastest way to get from Los Angeles to Great Smoky Mountains?

The quickest way to get from Los Angeles to Great Smoky Mountains is to fly and drive which takes 9 h 49 min and costs $270 - $480.

How long does it take to get from Los Angeles to Great Smoky Mountains?

It takes approximately 9 h 49 min to get from Los Angeles to Great Smoky Mountains, including transfers.