Directions from Long Island to Buffalo–Depew Station

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train to New York JFK, fly to Buffalo  •  5 h 45 min

  1. Take the train from Central Islip to Jamaica
  2. Fly from New York JFK (JFK) to Buffalo (BUF) JFK - BUF

$79 - $381

Cheapest option

Train, bus  •  15 h 16 min

  1. Take the train from Smithtown to Hunterspoint Avenue Babylon / ...
  2. Take the bus from New York, NY to Buffalo, NY

$52 - $77

9 alternative options

Fly Islip to Buffalo  •  6 h 23 min

  1. Fly from Islip (ISP) to Buffalo (BUF) ISP - BUF

$264 - $1,404

Train to New York La Guardia, fly to Buffalo  •  6 h 43 min

  1. Take the train from Central Islip to Woodside
  2. Fly from New York La Guardia (LGA) to Buffalo (BUF) LGA - BUF

$80 - $385

Train to New York JFK, fly to Rochester, train  •  7 h 4 min

  1. Take the train from Central Islip to Jamaica
  2. Fly from New York JFK (JFK) to Rochester (ROC) JFK - ROC
  3. Take the train from Rochester to Buffalo

$127 - $380

Train to Newark, fly to Buffalo  •  7 h 26 min

  1. Take the train from Ronkonkoma to Penn Station
  2. Fly from Newark (EWR) to Buffalo (BUF) EWR - BUF

$109 - $491

Train to New York La Guardia, fly to Rochester, train  •  7 h 42 min

  1. Take the train from Central Islip to Woodside
  2. Fly from New York La Guardia (LGA) to Rochester (ROC) LGA - ROC
  3. Take the train from Rochester to Buffalo

$128 - $494

Train VIA Rail  •  11 h 2 min

  1. Take the train from Ronkonkoma to Penn Station Ronkonkoma
  2. Take the train from New York to Buffalo VIA Rail

$73 - $228

Train Amtrak  •  11 h 21 min

  1. Take the train from Central Islip to Penn Station Ronkonkoma
  2. Take the train from New York Penn Station to Buffalo Depew Station Amtrak Empire Service / ...

$77 - $207

Bus  •  15 h 31 min

  1. Take the bus from Islip, NY to Binghamton, NY 495
  2. Take the bus from Binghamton, Ny to Buffalo, Ny 252 / ...

$74 - $141

Drive  •  7 h 43 min

  1. Drive from Centereach to Buffalo–Depew Station 425.6 miles

$40 - $60

What companies run services between Long Island, NY, USA and Buffalo–Depew Station, NY, USA?

Southwest Airlines, American Airlines and three other airlines fly from Holbrook to Buffalo–Depew Station hourly. Alternatively, you can take a train from Centereach to Buffalo–Depew Station via Ronkonkoma LIRR, Ronkonkoma, Penn Station, and New York in around 11 h 2 min.

Airlines
Delta
Website
delta.com
Flights from New York JFK to Buffalo
Ave. Duration
1 h 35 min
When
Every day
Estimated price
$90 - $650
Flights from New York La Guardia to Buffalo
Ave. Duration
1 h 33 min
When
Every day
Estimated price
$100 - $700
Flights from New York JFK to Rochester
Ave. Duration
1 h 31 min
When
Every day
Estimated price
$90 - $500
Flights from New York La Guardia to Rochester
Ave. Duration
1 h 27 min
When
Every day
Estimated price
$90 - $600
Southwest Airlines
Website
southwest.com
Flights from Islip to Buffalo via Baltimore
Ave. Duration
4 h 42 min
When
Every day
Estimated price
$290 - $1,300
Flights from Islip to Buffalo via Orlando
Ave. Duration
6 h 45 min
When
Every day
Estimated price
$500 - $1,900
United Airlines
Website
united.com
Flights from New York La Guardia to Buffalo via Washington Dulles
Ave. Duration
3 h 43 min
When
Every day
Estimated price
$220 - $1,600
Flights from Newark to Buffalo
Ave. Duration
1 h 24 min
When
Every day
Estimated price
$120 - $850
Flights from New York La Guardia to Rochester via Toronto
Ave. Duration
3 h 32 min
When
Every day
Estimated price
$160 - $700
Flights from New York La Guardia to Rochester via Washington Dulles
Ave. Duration
3 h 36 min
When
Every day
Estimated price
$200 - $1,200
JetBlue Airways
Website
jetblue.com
Flights from New York JFK to Buffalo
Ave. Duration
1 h 26 min
When
Every day
Estimated price
$100 - $650
Flights from New York JFK to Rochester
Ave. Duration
1 h 21 min
When
Every day
Estimated price
$100 - $600
American Airlines
Website
aa.com
Flights from Islip to Buffalo via Philadelphia
Ave. Duration
4 h 2 min
When
Every day
Estimated price
$260 - $1,400
Flights from New York La Guardia to Buffalo via Philadelphia
Ave. Duration
3 h 48 min
When
Every day
Estimated price
$130 - $800
Flights from New York La Guardia to Rochester via Boston
Ave. Duration
3 h 36 min
When
Monday to Friday
Estimated price
$110 - $750
Air Canada
Website
aircanada.com
Flights from New York La Guardia to Rochester via Toronto
Ave. Duration
3 h 25 min
When
Every day
Estimated price
$160 - $700
Train operators
Long Island Rail Road
Website
mta.info
Train from Central Islip to Jamaica
Ave. Duration
51 min
Frequency
Hourly
Estimated price
$8 - $12
Schedules at
mta.info
Train from Central Islip to Woodside
Ave. Duration
1 h 4 min
Frequency
Hourly
Estimated price
$9 - $14
Schedules at
mta.info
Train from Ronkonkoma to Penn Station
Ave. Duration
1 h 22 min
Frequency
Hourly
Estimated price
$11 - $16
Schedules at
mta.info
Train from Central Islip to Penn Station
Ave. Duration
1 h 15 min
Frequency
Hourly
Estimated price
$10 - $15
Schedules at
mta.info
Train from Smithtown to Hunterspoint Avenue
Ave. Duration
1 h 21 min
Frequency
3 times a day
Estimated price
$10 - $15
Schedules at
mta.info
VIA Rail
Phone
+1 1 888 842-7245
Website
viarail.ca
Train from Rochester to Buffalo
Ave. Duration
1 h 6 min
Frequency
Every 3 hours
Estimated price
$24 - $70
Website
viarail.ca
Escape
$24 - $35
Economy
$30 - $45
Economy Plus
$50 - $70
Business
$40 - $60
Business Plus/Sleeper
$80 - $110
Train from New York to Buffalo
Ave. Duration
7 h 55 min
Frequency
Every 3 hours
Estimated price
$60 - $210
Website
viarail.ca
Escape
$60 - $85
Economy
$100 - $140
Economy Plus
$140 - $210
Business
$150 - $210
Business Plus/Sleeper
$270 - $380
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Rochester Amtrak to Buffalo Depew Station Amtrak
Ave. Duration
46 min
Frequency
5 times a day
Estimated price
$25 - $50
Website
amtrak.com
Coach Seat
$25 - $40
Flexi Coach Seat
$45 - $65
Business Coach Seat
$35 - $50
Room
$140 - $200
Train from New York Penn Station to Buffalo Depew Station Amtrak
Ave. Duration
7 h 42 min
Frequency
4 times a day
Estimated price
$65 - $190
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$120 - $180
Business Coach Seat
$130 - $190
Room
$290 - $410
Bus operators
Greyhound USA
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Binghamton, Ny to Buffalo, Ny
Ave. Duration
5 h 5 min
Frequency
Hourly
Estimated price
$28 - $70
Website
greyhound.com
Economy
$28 - $45
Flexible
$50 - $70

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Questions & Answers

The distance between Long Island and Buffalo–Depew Station is 523 km. The road distance is 681 km.

The cheapest way to get from Long Island to Buffalo–Depew Station is to drive which costs $40 - $60 and takes 7 h 43 min.

The quickest way to get from Long Island to Buffalo–Depew Station is to train and fly which takes 5 h 45 min and costs $75 - $390.

No, there is no direct bus from Long Island to Buffalo–Depew Station. However, there are services departing from Hammond Lane and arriving at Walden Ave & 2929 Walden via Smithtown LIRR, Islip, NY, Binghamton, Ny, Ellicott St & North Division St and Galleria Drway & Green Parking Entrance. The journey, including transfers, takes approximately 15 h 31 min.

It takes approximately 5 h 45 min to get from Long Island to Buffalo–Depew Station, including transfers.