There are 8 ways to get from Lisle to Pittsburgh by train, subway, plane, bus, train (Amtrak), bus (Flixbus), car, or bus (Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Train, subway to Chicago Midway International Airport, fly to Pittsburgh International Airport, bus
best- Take the train from Lisle to Chicago Union Stationtrain
- Take the subway from LaSalle/Van Buren to Midwaysubway
- Fly from Chicago Midway International Airport (MDW) to Pittsburgh International Airport (PIT)plane MDW - PIT
- Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus
5h 54mBus
cheapest- Take the bus from Chicago Bus Station to Pittsburgh Intermodal Stationbus Greyhound US0164
14h 6m$61–117Train (Amtrak)
- Take the train from Chicago Union Station to Pittsburgh Amtrak Stationtrain Floridian
11h 23m$80–206Bus via Auburn Gresham (Flixbus)
- Take the bus from Chicago to Pittsburgh Intermodal Stationbus FlixBus N2640
13h 14m$67–121Drive 477.6 mi
- Drive from Lisle to Pittsburghcar 477.6 mi
8h 7m$88–126Train to Chicago O'Hare International Airport, fly to Pittsburgh International Airport, bus
- Take the train from Lisle to Chicago Union Stationtrain
- Fly from Chicago O'Hare International Airport (ORD) to Pittsburgh International Airport (PIT)plane ORD - PIT
- Take the bus from Pittsburgh International Airport to Seventh Ave + William Penn Plbus
6h 8mFly Chicago O'Hare International Airport to Morgantown Municipal Airport, bus
- Fly from Chicago O'Hare International Airport (ORD) to Morgantown Municipal Airport (MGW)plane ORD - MGW
- Take the bus from Mountaineer Station to Pittsburgh Greyhoundbus
8h 4m$66–355Fly Chicago O'Hare International Airport to Johnstown-Cambria County Airport, train
- Fly from Chicago O'Hare International Airport (ORD) to Johnstown-Cambria County Airport (JST)plane ORD - JST
- Take the train from Johnstown Amtrak Station to Pittsburgh Amtrak Stationtrain
7h 52m$89–351
Lisle to Pittsburgh by train (Amtrak)
Questions & Answers
The cheapest way to get from Lisle to Pittsburgh is to bus which costs $60 - $120 and takes 14h 6m.
The fastest way to get from Lisle to Pittsburgh is to fly and train which takes 7h 52m and costs $85 - $360.
No, there is no direct bus from Lisle to Pittsburgh station. However, there are services departing from Ogden Ave / Spencer Ave and arriving at Pittsburgh Intermodal Station via Yorktown Center, 54th/Cermak Pink Line Station and Chicago Bus Station. The journey, including transfers, takes approximately 14h 6m.
No, there is no direct train from Lisle to Pittsburgh station. However, there are services departing from Lisle and arriving at Pittsburgh Amtrak Station via Chicago Union Station. The journey, including transfers, takes approximately 11h 23m.
The distance between Lisle and Pittsburgh is 465 miles. The road distance is 480.4 miles.
The best way to get from Lisle to Pittsburgh without a car is to train which takes 11h 23m and costs $75 - $210.
It takes approximately 5h 54m to get from Lisle to Pittsburgh, including transfers.
Lisle to Pittsburgh bus services, operated by Greyhound USA, depart from Chicago Bus Station.
Lisle to Pittsburgh train services, operated by Amtrak, depart from Chicago Union Station.
The best way to get from Lisle to Pittsburgh is to train which takes 11h 23m and costs $75 - $210. Alternatively, you can bus via Auburn Gresham, which costs $65 - $130 and takes 13h 14m.
What companies run services between Lisle, IL, USA and Pittsburgh, PA, USA?
Amtrak operates a train from Chicago Union Station to Pittsburgh Amtrak Station once daily. Tickets cost $75–200 and the journey takes 9h 25m. Alternatively, Flixbus USA operates a bus from Chicago to Pittsburgh Intermodal Station once daily. Tickets cost $60–110 and the journey takes 10h 35m.
- Website
- united.com
Flights from Chicago O'Hare International Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 38m
- When
- Every day
- Estimated price
- $50–320
Flights from Chicago O'Hare International Airport to Morgantown Municipal Airport
- Ave. Duration
- 1h 42m
- When
- Every day
- Estimated price
- $45–300
Flights from Chicago O'Hare International Airport to Morgantown Municipal Airport via Washington Dulles
- Ave. Duration
- 4h 13m
- When
- Every day
- Estimated price
- $60–340
Flights from Chicago O'Hare International Airport to Johnstown-Cambria County Airport
- Ave. Duration
- 1h 50m
- When
- Every day
- Estimated price
- $50–300
Flights from Chicago O'Hare International Airport to Johnstown-Cambria County Airport via Washington Dulles
- Ave. Duration
- 4h 8m
- When
- Every day
- Estimated price
- $60–340
- Website
- aa.com
Flights from Chicago O'Hare International Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 37m
- When
- Every day
- Estimated price
- $50–320
- Website
- southwest.com
Flights from Chicago Midway International Airport to Pittsburgh International Airport
- Ave. Duration
- 1h 22m
- When
- Every day
- Estimated price
- $70–440
- Website
- delta.com
Flights from Chicago Midway International Airport to Pittsburgh International Airport via Detroit
- Ave. Duration
- 3h 33m
- When
- Saturday
- Estimated price
- $70–450
- Phone
- +1 312-322-6777
- Website
- metra.com
Train from Lisle to Chicago Union Station
- Ave. Duration
- 58 min
- Frequency
- Hourly
- Estimated price
- $4–6
- Website
- https://metra.com
- Adult
- $4–6
- Phone
- +1 888-968-7282
- Website
- transitchicago.com
Subway from LaSalle/Van Buren to Midway
- Ave. Duration
- 33 min
- Frequency
- Every 15 minutes
- Estimated price
- $2–5
- Website
- https://www.transitchicago.com
- Schedules at
- https://www.transitchicago.com/schedules/
- Adult
- $2–5
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Pittsburgh Amtrak Station
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $75–200
- Website
- https://www.amtrak.com/home.html
Train from Johnstown Amtrak Station to Pittsburgh Amtrak Station
- Ave. Duration
- 1h 51m
- Frequency
- Once daily
- Estimated price
- $18–22
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 412-442-2000
- Website
- rideprt.org
Bus from Pittsburgh International Airport to Seventh Ave + William Penn Pl
- Ave. Duration
- 47 min
- Frequency
- Hourly
- Website
- https://www.rideprt.org
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Chicago to Pittsburgh Intermodal Station
- Ave. Duration
- 10h 35m
- Frequency
- Once daily
- Estimated price
- $60–110
- Schedules at
- flixbus.com
- Adult
- $60–110
Bus from Chicago Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 11h
- Frequency
- Once daily
- Estimated price
- $60–100
- Schedules at
- flixbus.com
- Phone
- +1 304-291-7433
- Website
- busride.org
Bus from Mountaineer Station to Pittsburgh Greyhound
- Ave. Duration
- 2h 15m
- Frequency
- Twice daily
- Estimated price
- $3–30
- Website
- https://www.busride.org
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Chicago Bus Station to Pittsburgh Intermodal Station
- Ave. Duration
- 10h 10m
- Frequency
- Twice daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Lisle to Pittsburgh bus services, operated by Greyhound USA, arrive at Pittsburgh Intermodal Station.
Pittsburgh is 1h ahead of Lisle. It is currently 2:13 PM in Lisle and 3:13 PM in Pittsburgh.
Lisle to Pittsburgh train services, operated by Amtrak, arrive at Pittsburgh Amtrak Station.
Yes, the driving distance between Lisle to Pittsburgh is 480 miles. It takes approximately 8h 7m to drive from Lisle to Pittsburgh.
There are 214+ hotels available in Pittsburgh.













