There are 7 ways to get from Lexington to Tupelo by car, bus, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive, bus via Nashville
best- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Nashvillebus
- Take the bus from Nashville Bus Station to Memphis Bus Stationbus
- Take the bus from Memphis Bus Station to Tupelobus
14h 5m$111–205Fly Blue Grass Airport to Golden Triangle Regional Airport, drive
cheapest- Fly from Blue Grass Airport (LEX) to Golden Triangle Regional Airport (GTR)plane LEX - GTR
- Drive from Golden Triangle Regional Airport (GTR) to Tupelocar
8h 54m$68–369Drive 411.5 mi
- Drive from Lexington to Tupelocar 411.5 mi
8h 3m$76–109Drive, bus
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from La Tropicana - Louisville, KY to Tornado Bus Co - West Memphisbus
- Take the bus from Memphis Bus Station to Tupelobus
16h 6m$136–299Drive to Louisville International Airport, fly to Tupelo Regional Airport
- Drive from Lexington to Louisville-Airport-SDFcar
- Fly from Louisville International Airport (SDF) to Tupelo Regional Airport (TUP)plane SDF - TUP
7h 10m$170–691Drive to Covington, fly to Tupelo Regional Airport
- Drive from Lexington to Covington (CVG)car
- Fly from Covington (CVG) to Tupelo Regional Airport (TUP)plane CVG - TUP
7h 2m$151–842Drive, bus to Nashville, fly to Tupelo Regional Airport
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Nashvillebus
- Fly from Nashville (BNA) to Tupelo Regional Airport (TUP)plane BNA - TUP
9h 47m$147–485
Blue Grass Airport (LEX) to Golden Triangle Regional Airport (GTR) flights
Questions & Answers
The cheapest way to get from Lexington to Tupelo is to drive which costs $75 - $110 and takes 8h 3m.
The fastest way to get from Lexington to Tupelo is to drive and fly which takes 7h 2m and costs $150 - $850.
The distance between Lexington and Tupelo is 576 miles. The road distance is 413.9 miles.
It takes approximately 14h 5m to get from Lexington to Tupelo, including transfers.
Tupelo is 1h behind Lexington. It is currently 3:30 PM in Lexington and 2:30 PM in Tupelo.
Yes, the driving distance between Lexington to Tupelo is 414 miles. It takes approximately 8h 3m to drive from Lexington to Tupelo.
There are 27+ hotels available in Tupelo.
What companies run services between Lexington, KY, USA and Tupelo, MS, USA?
There is no direct connection from Lexington to Tupelo. However, you can drive to Middletown Station @ Target, take the line 31 bus to S 5th @ W Jefferson, walk to W Jefferson @ S 6th, take the line 10 bus to W Broadway @ S 10th, walk to Louisville, KY, take the bus to Nashville, take the bus to Memphis Bus Station, take the bus to Tupelo, then take the taxi to Tupelo. Alternatively, you can drive from Lexington to Tupelo in around 8h 3m.
- Website
- contouraviation.com
Flights from Louisville International Airport to Tupelo Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 6h 38m
- When
- Every day
- Estimated price
- $180–900
Flights from Louisville International Airport to Tupelo Regional Airport via Nashville
- Ave. Duration
- 8h 5m
- When
- Sunday
- Estimated price
- $140–650
Flights from Louisville International Airport to Tupelo Regional Airport via Atlanta, Nashville
- Ave. Duration
- 6h 51m
- When
- Every day
- Estimated price
- $120–750
Flights from Louisville International Airport to Tupelo Regional Airport via Charlotte, Nashville
- Ave. Duration
- 7h 55m
- When
- Every day
- Estimated price
- $140–750
Flights from Covington to Tupelo Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $240–1,200
Flights from Covington to Tupelo Regional Airport via Nashville
- Ave. Duration
- 6h 25m
- When
- Sunday
- Estimated price
- $120–800
Flights from Covington to Tupelo Regional Airport via Detroit, Nashville
- Ave. Duration
- 9h 25m
- When
- Every day
- Estimated price
- $180–1,000
Flights from Covington to Tupelo Regional Airport via Atlanta, Nashville
- Ave. Duration
- 7h 27m
- When
- Every day
- Estimated price
- $170–950
Flights from Nashville to Tupelo Regional Airport
- Ave. Duration
- 1h 5m
- When
- Every day
- Estimated price
- $85–390
- Website
- delta.com
Flights from Blue Grass Airport to Golden Triangle Regional Airport via Atlanta
- Ave. Duration
- 6h 29m
- When
- Every day
- Estimated price
- $55–350
Flights from Blue Grass Airport to Golden Triangle Regional Airport via Reagan Washington, Atlanta
- Ave. Duration
- 7h 38m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–470
- Website
- aa.com
Flights from Blue Grass Airport to Golden Triangle Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 56m
- When
- Every day
- Estimated price
- $100–480
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Louisville, KY to Nashville
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Nashville Bus Station to Memphis Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $40–70
- Website
- https://www.greyhound.com/
Bus from Memphis Bus Station to Tupelo
- Ave. Duration
- 1h 40m
- Frequency
- Twice daily
- Estimated price
- $17–50
- Website
- https://www.greyhound.com/
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from La Tropicana - Louisville, KY to Tornado Bus Co - West Memphis
- Ave. Duration
- 7h 44m
- Frequency
- 3 times a week
- Estimated price
- $75–190
- Schedules at
- tornadobus.com
- Adults 11-59
- $75–190
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