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How to get fromLexington to TupeloBy car, bus, or plane

Find Transport to Tupelo

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There are 6 ways to get from Lexington to Tupelo by car, bus, or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive, bus via Nashville

    best
    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Nashvillebus bus
    3. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    13h 59m
    $101–187

  2. Drive 411.5 mi

    cheapest
    1. Drive from Lexington to Tupelocar car 411.5 mi
    8h 3m
    $76–109

  3. Fly Blue Grass Airport to Golden Triangle Regional Airport, drive

    1. Fly from Blue Grass Airport (LEX) to Golden Triangle Regional Airport (GTR)plane plane LEX - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    8h 33m
    $98–569

  4. Drive, bus

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from La Tropicana - Louisville, KY to Tornado Bus Co - West Memphisbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    16h 11m
    $140–291

  5. Drive to Louisville International Airport, fly to Tupelo Regional Airport

    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Tupelo Regional Airport (TUP)plane plane SDF - TUP
    5h 33m
    $158–469

  6. Drive to Covington, fly to Tupelo Regional Airport

    1. Drive from Lexington to Covington (CVG)car car
    2. Fly from Covington (CVG) to Tupelo Regional Airport (TUP)plane plane CVG - TUP
    7h 7m
    $114–590

Blue Grass Airport (LEX) to Golden Triangle Regional Airport (GTR) flights

Calendar34Weekly Planes
Duration6h 35mAverage Duration
Ticket$88Cheapest Price
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Questions & Answers

What companies run services between Lexington, KY, USA and Tupelo, MS, USA?

There is no direct connection from Lexington to Tupelo. However, you can drive to Middletown Station @ Target, take the line 31 bus to S 5th @ W Jefferson, walk to W Jefferson @ S 6th, take the line 10 bus to W Broadway @ S 10th, walk to Louisville, KY, take the bus to Nashville, take the bus to Memphis Bus Station, take the bus to Tupelo, then take the taxi to Tupelo. Alternatively, you can drive from Lexington to Tupelo in around 8h 3m.

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