Rome2Rio

How to get fromLexington to Tupeloby plane, car or bus

Find Transport to Tupelo

See all options

There are 6 ways to get from Lexington to Tupelo by plane, car, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Blue Grass Airport to Golden Triangle Regional Airport, drive

    best
    1. Fly from Blue Grass Airport (LEX) to Golden Triangle Regional Airport (GTR)plane plane LEX - GTR
    2. Drive from Golden Triangle Regional Airport (GTR) to Tupelocar car
    7h 51m
    $68–369

  2. Drive, bus via Nashville

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from Louisville, KY to Nashvillebus bus
    3. Take the bus from Nashville Bus Station to Memphis Bus Stationbus bus
    4. Take the bus from Memphis Bus Station to Tupelobus bus
    14h 5m
    $111–174

  3. Drive 411.5 mi

    1. Drive from Lexington to Tupelocar car 411.5 mi
    8h 3m
    $76–109

  4. Drive to Louisville International Airport, fly to Tupelo Regional Airport

    1. Drive from Lexington to Louisville-Airport-SDFcar car
    2. Fly from Louisville International Airport (SDF) to Tupelo Regional Airport (TUP)plane plane SDF - TUP
    7h 10m
    $160–691

  5. Drive to Covington, fly to Tupelo Regional Airport

    1. Drive from Lexington to Covington (CVG)car car
    2. Fly from Covington (CVG) to Tupelo Regional Airport (TUP)plane plane CVG - TUP
    7h 47m
    $151–842

  6. Drive, bus

    1. Drive from Lexington to Middletown Station @ Targetcar car
    2. Take the bus from La Tropicana - Louisville, KY to Tornado Bus Co - West Memphisbus bus
    3. Take the bus from Memphis Bus Station to Tupelobus bus
    16h 6m
    $136–278

Blue Grass Airport (LEX) to Golden Triangle Regional Airport (GTR) flights

Calendar18Weekly Planes
Duration5h 23mAverage Duration
Ticket$58Cheapest Price
See schedules

Questions & Answers

What companies run services between Lexington, KY, USA and Tupelo, MS, USA?

There is no direct connection from Lexington to Tupelo. However, you can take the line 3 bus to Transit Center, take the line 8 bus to Terminal @ Bluegrass Field, walk to Blue Grass Airport (LEX) airport, fly to Golden Triangle Regional Airport (GTR), then drive to Tupelo. Alternatively, you can take a vehicle from Lexington to Tupelo via Middletown Station @ Target, S 5th @ W Jefferson, W Jefferson @ S 6th, W Broadway @ S 10th, Louisville, KY, Nashville Bus Station, Memphis Bus Station, and Tupelo in around 14h 5m.

Airlines
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Lexington

Trips to Tupelo

Popular routes