Rome2Rio

How to get fromLexington to San Diegoby car, plane, bus or train

Find Transport to San Diego

See all options

There are 4 ways to get from Lexington to San Diego by car, plane, bus, or train

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Louisville International Airport, fly

    best
    1. Drive from Lexington to Louisville-Airport-SDFcar
    2. Fly from Louisville International Airport (SDF) to San Diego International Airport (SAN)planeSDF - SAN
    7h 49m
    $234–971

  2. Drive, bus, train (Amtrak)

    1. Drive from Lexington to Middletown Station @ Targetcar
    2. Take the bus from Louisville, KY to Chicago Union Stationbus
    3. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain
    4. Take the train from Fullerton Amtrak Station to San Diegotrain
    2d 8h
    $247–557

  3. Drive 2,135.1 mi

    1. Drive from Lexington to San Diegocar2,135.1 mi
    34h 42m
    $390–563

  4. Fly from Blue Grass Airport

    1. Fly from Blue Grass Airport (LEX) to San Diego International Airport (SAN)planeLEX - SAN
    9h 48m
    $282–1,202

Louisville International Airport (SDF) to San Diego International Airport (SAN) flights

Calendar74Weekly Planes
Duration7h 10mAverage Duration
Ticket$221Cheapest Price
See schedules

Questions & Answers

What companies run services between Lexington, KY, USA and San Diego, CA, USA?

American Airlines, United Airlines, and two other airlines fly from Blue Grass Airport (LEX) to San Diego International Airport (SAN) hourly.

Transport is disrupted due to the Russia-Ukraine war. Read more

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Where to next?

Trips from Lexington

Trips to San Diego

Popular routes