Rome2Rio

How to get fromLexington to Port Saint Lucieby car, plane, bus, bus (Greyhound, Flixbus), taxi or bus (Greyhound)

Find Transport to Port Saint Lucie

See all options

There are 8 ways to get from Lexington to Port Saint Lucie by car, plane, bus, bus (Greyhound, Flixbus), taxi, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Drive to Louisville International Airport, fly to Orlando, bus

    best
    1. Drive from Lexington to Louisville-Airport-SDFcar
    2. Fly from Louisville International Airport (SDF) to Orlando (MCO)planeSDF - MCO
    3. Take the bus from Orlando - RedCoach Station, FL to Fort Piercebus
    6h 39m
    $125–393

  2. Fly Blue Grass Airport to Fort Lauderdale–Hollywood International Airport, bus

    cheapest
    1. Fly from Blue Grass Airport (LEX) to Fort Lauderdale–Hollywood International Airport (FLL)planeLEX - FLL
    2. Take the bus from Fort Lauderdale - Broward Blvd Park and Ride to Fort Piercebus
    9h 7m
    $121–517

  3. Bus via Oak Ridge

    1. Take the bus from Lexington Bus Stop to Atlanta Bus Stationbus
    2. Take the bus from Atlanta Bus Station to Orlandobus
    3. Take the bus from Orlando - RedCoach Station, FL to Fort Piercebus
    23h 22m
    $132–333

  4. Drive 908.8 mi

    1. Drive from Lexington to Port Saint Luciecar908.8 mi
    15h 13m
    $166–240

  5. Drive to Mcghee Tyson Airport, fly to Orlando Sanford, drive

    1. Drive from Lexington to Mcghee Tyson Airport (TYS)car
    2. Fly from Mcghee Tyson Airport (TYS) to Orlando Sanford (SFB)planeTYS - SFB
    3. Drive from Orlando-Sanford-Airport-SFB to Port Saint Luciecar
    7h 7m
    $147–632

  6. Fly Blue Grass Airport to Orlando Sanford, drive

    1. Fly from Blue Grass Airport (LEX) to Orlando Sanford (SFB)planeLEX - SFB
    2. Drive from Orlando-Sanford-Airport-SFB to Port Saint Luciecar
    7h 16m
    $136–637

  7. Fly Blue Grass Airport to Melbourne International Airport, taxi, bus

    1. Fly from Blue Grass Airport (LEX) to Melbourne International Airport (MLB)planeLEX - MLB
    2. Take the taxi from Melbourne International Airport (MLB) to Sebastiantaxi
    3. Take the bus from Sebastian to Port St Luciebus
    11h 34m
    $215–797

  8. Bus (Greyhound)

    1. Take the bus from Lexington Bus Stop to Atlanta Bus StationbusGreyhound US0110
    2. Take the bus from Atlanta Bus Station to Fort PiercebusGreyhound US0630
    27h 30m
    $151–371

Lexington to Port Saint Lucie by bus

Calendar5Weekly Buses
Duration23h 22mAverage Duration
Ticket$132Cheapest Price
See schedules

Questions & Answers

What companies run services between Lexington, KY, USA and Port Saint Lucie, FL, USA?

You can take a bus from Tates Creek @ Dove Run to Fort Pierce via Transit Center, Walmart @ Northpark, Lexington Bus Stop, Atlanta Bus Station, Orlando, Florida Mall Ave And Crystal Clear Ln, Mccoy Rd And Central Ave, and Orlando - RedCoach Station, FL in around 23h 22m.

Airlines
Bus operators
Other operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

Trips from Lexington

Trips to Port Saint Lucie

Popular routes