There are 6 ways to get from Lexington to Panama City Beach by car, plane, bus (Greyhound, Flixbus), or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Louisville International Airport, fly to Northwest Florida Beaches International Airport
best- Drive from Lexington to Louisville-Airport-SDF
- Fly from Louisville International Airport (SDF) to Northwest Florida Beaches International Airport (ECP)SDF - ECP
5h 34m$144–536Drive 636.4 mi
cheapest- Drive from Lexington to Panama City Beach636.4 mi
11h 59m$117–168Bus
- Take the bus from Lexington Bus Stop to Atlanta Bus Station
- Take the bus from Atlanta Bus Station to Tallahassee
- Take the bus from Tallahassee to Panama City Beach Bus Station
18h 26m$165–345Drive to Louisville International Airport, fly to Destin–Fort Walton Beach Airport, taxi
- Drive from Lexington to Louisville-Airport-SDF
- Fly from Louisville International Airport (SDF) to Destin–Fort Walton Beach Airport (VPS)SDF - VPS
- Take the taxi from Destin–Fort Walton Beach Airport (VPS) to Panama City Beach
4h 29m$234–641Fly Blue Grass Airport to Northwest Florida Beaches International Airport
- Fly from Blue Grass Airport (LEX) to Northwest Florida Beaches International Airport (ECP)LEX - ECP
7h 6m$152–667Fly Blue Grass Airport to Destin–Fort Walton Beach Airport, taxi
- Fly from Blue Grass Airport (LEX) to Destin–Fort Walton Beach Airport (VPS)LEX - VPS
- Take the taxi from Destin–Fort Walton Beach Airport (VPS) to Panama City Beach
5h 55m$242–772
Louisville International Airport (SDF) to Northwest Florida Beaches International Airport (ECP) flights
Questions & Answers
The cheapest way to get from Lexington to Panama City Beach is to drive which costs $110 - $170 and takes 11h 59m.
The fastest way to get from Lexington to Panama City Beach is to drive and fly and taxi which takes 4h 29m and costs $230 - $650.
The distance between Lexington and Panama City Beach is 643 miles. The road distance is 640.1 miles.
The best way to get from Lexington to Panama City Beach without a car is to bus which takes 18h 26m and costs $160 - $350.
It takes approximately 5h 34m to get from Lexington to Panama City Beach, including transfers.
The best way to get from Lexington to Panama City Beach is to bus which takes 18h 26m and costs $160 - $350. Alternatively, you can fly, which costs $150 - $700 and takes 7h 6m.
Panama City Beach is 1h behind Lexington. It is currently 9:28 PM in Lexington and 8:28 PM in Panama City Beach.
Yes, the driving distance between Lexington to Panama City Beach is 640 miles. It takes approximately 11h 59m to drive from Lexington to Panama City Beach.
There are 5361+ hotels available in Panama City Beach.
What companies run services between Lexington, KY, USA and Panama City Beach, FL, USA?
You can take a vehicle from Lexington to Panama City Beach via Lexington Bus Stop, Atlanta Bus Station, Tallahassee, and Panama City Beach Bus Station in around 18h 26m. Alternatively, Delta and American Airlines fly from Blue Grass Airport (LEX) to Northwest Florida Beaches International Airport (ECP) every 4 hours.
- Website
- delta.com
Flights from Louisville International Airport to Northwest Florida Beaches International Airport via Atlanta
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $80–450
Flights from Louisville International Airport to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 3h 54m
- When
- Every day
- Estimated price
- $80–460
Flights from Blue Grass Airport to Northwest Florida Beaches International Airport via Atlanta
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $100–600
Flights from Blue Grass Airport to Destin–Fort Walton Beach Airport via Atlanta
- Ave. Duration
- 3h 52m
- When
- Every day
- Estimated price
- $100–600
- Website
- aa.com
Flights from Louisville International Airport to Northwest Florida Beaches International Airport via Charlotte
- Ave. Duration
- 6h 27m
- When
- Every day
- Estimated price
- $95–500
Flights from Louisville International Airport to Northwest Florida Beaches International Airport via Reagan Washington
- Ave. Duration
- 8h 5m
- When
- Wednesday
- Estimated price
- $130–650
Flights from Blue Grass Airport to Northwest Florida Beaches International Airport via Chicago O'Hare
- Ave. Duration
- 5h 26m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $150–750
Flights from Blue Grass Airport to Northwest Florida Beaches International Airport via Charlotte
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $110–650
Flights from Blue Grass Airport to Northwest Florida Beaches International Airport via Dallas/Ft.Worth
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $180–850
- Website
- southwest.com
Flights from Louisville International Airport to Northwest Florida Beaches International Airport via Chicago Midway
- Ave. Duration
- 4h 30m
- When
- Thursday
- Estimated price
- $120–600
Flights from Louisville International Airport to Northwest Florida Beaches International Airport via Dallas
- Ave. Duration
- 7h
- When
- Monday, Tuesday, Friday, and Sunday
- Estimated price
- $140–650
- Website
- allegiantair.com
Flights from Louisville International Airport to Destin–Fort Walton Beach Airport
- Ave. Duration
- 1h 38m
- When
- Tuesday and Saturday
- Estimated price
- $80–450
Flights from Blue Grass Airport to Destin–Fort Walton Beach Airport
- Ave. Duration
- 1h 36m
- When
- Friday
- Estimated price
- $100–600
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Lexington Bus Stop to Atlanta Bus Station
- Ave. Duration
- 7h 50m
- Frequency
- Once daily
- Estimated price
- $70–190
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Tallahassee
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- $35–75
- Website
- https://www.greyhound.com/
Bus from Tallahassee to Panama City Beach Bus Station
- Ave. Duration
- 2h 10m
- Frequency
- Twice daily
- Estimated price
- $17–29
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Atlanta Bus Station to Tallahassee
- Ave. Duration
- 6h 10m
- Frequency
- Once daily
- Estimated price
- $35–65
- Schedules at
- flixbus.com
- Ave. Duration
- 1h 21m
- Estimated price
- $140–170
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
Quickie Taxi
- Phone
- +1 850-716-6545
- Website
- quickietaxi.com
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