There are 3 ways to get from Lexington to Great Smoky Mountains National Park by bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, drive  •  21 h 57 min

  1. Take the bus from Lexington, Ky to Cincinnati, Oh
  2. Take the bus from Cincinnati, Oh to Columbus, Oh
  3. Take the bus from Columbus, Oh to Winston Salem, Nc
  4. Take the bus from Winston Salem, Nc to Asheville, Nc
  5. Drive from Asheville, Nc to Great Smoky Mountains National Park

$98 - $247

2 alternative options

Drive  •  4 h 7 min

  1. Drive from Lexington to Great Smoky Mountains National Park 230 miles

$22 - $35

Fly, drive  •  7 h 52 min

  1. Fly from Lexington (LEX) to Knoxville (TYS) LEX - TYS
  2. Drive from Knoxville to Great Smoky Mountains National Park

$227 - $961

Questions & Answers

The cheapest way to get from Lexington to Great Smoky Mountains National Park is to drive which costs $22 - $35 and takes 4 h 7 min.

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The quickest way to get from Lexington to Great Smoky Mountains National Park is to drive which costs $22 - $35 and takes 4 h 7 min.

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The distance between Lexington and Great Smoky Mountains National Park is 174 miles. The road distance is 230 miles.

Get driving directions

It takes approximately 21 h 57 min to get from Lexington to Great Smoky Mountains National Park, including transfers.

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The best way to get from Lexington to Great Smoky Mountains National Park without a car is to bus and drive which takes 21 h 57 min and costs $95 - $250.

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Map of how to get from Lexington to Great Smoky Mountains National Park.
Launch map view
  • Distance: 174.5 miles
  • Duration: 21 h 57 min

What companies run services between Lexington, KY, USA and Great Smoky Mountains National Park, TN, USA?

There is no direct connection from Lexington to Great Smoky Mountains National Park. However, you can take the line 3 bus to Transit Center, take the line 4 bus to Walmart @ Northpark, take the walk to Lexington, Ky, take the bus to Cincinnati, Oh, take the bus to Columbus, Oh, take the bus to Winston Salem, Nc, take the bus to Asheville, Nc, then take the drive to Great Smoky Mountains National Park. Alternatively, you can take the drive to Great Smoky Mountains National Park.

Airlines
Delta
Website
delta.com
Flights from Lexington to Knoxville via Atlanta
Ave. Duration
4 h 5 min
When
Every day
Estimated price
$200 - $1,100
Flights from Lexington to Knoxville via Detroit
Ave. Duration
4 h 25 min
When
Every day
Estimated price
$220 - $1,200
American Airlines
Website
aa.com
Flights from Lexington to Knoxville via Charlotte
Ave. Duration
4 h 59 min
When
Every day
Estimated price
$210 - $1,100
Flights from Lexington to Knoxville via Chicago O'Hare
Ave. Duration
4 h 40 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$250 - $1,200
Flights from Lexington to Knoxville via Philadelphia
Ave. Duration
5 h 37 min
When
Every day
Estimated price
$270 - $1,200
United Airlines
Website
united.com
Flights from Lexington to Knoxville via Chicago O'Hare
Ave. Duration
5 h 49 min
When
Every day
Estimated price
$260 - $1,200
Allegiant Air
Website
allegiantair.com
Flights from Lexington to Knoxville via Orlando Sanford
Ave. Duration
5 h 54 min
When
Monday, Wednesday and Friday
Estimated price
$220 - $950
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Lexington, Ky to Cincinnati, Oh
Ave. Duration
1 h 25 min
Frequency
Every 30 minutes
Estimated price
$14 - $35
Website
greyhound.com
Economy
$14 - $21
Flexible
$25 - $35
Bus from Cincinnati, Oh to Columbus, Oh
Ave. Duration
1 h 45 min
Frequency
Hourly
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $25
Flexible
$29 - $40
Bus from Columbus, Oh to Winston Salem, Nc
Ave. Duration
10 h 35 min
Frequency
Hourly
Estimated price
$40 - $110
Website
greyhound.com
Economy
$40 - $70
Flexible
$80 - $110
Bus from Winston Salem, Nc to Asheville, Nc
Ave. Duration
2 h 55 min
Frequency
Every 2 hours
Estimated price
$20 - $50
Website
greyhound.com
Economy
$20 - $30
Flexible
$35 - $50

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Trips to Great Smoky Mountains National Park