There are 6 ways to get from Lexington to Florida Keys by car, plane, bus (Greyhound), or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Louisville International Airport, fly to Key West International Airport
best- Drive from Lexington to Louisville-Airport-SDFcar
- Fly from Louisville International Airport (SDF) to Key West International Airport (EYW)plane SDF - EYW
8h 26m$191–790Bus (Greyhound)
cheapest- Take the bus from Lexington Bus Stop to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Big Pine Keybus
31h 9m$139–365Drive 1,140.3 mi
- Drive from Lexington to Florida Keyscar 1,140.3 mi
20h 25m$209–301Fly Blue Grass Airport to Key West International Airport
- Fly from Blue Grass Airport (LEX) to Key West International Airport (EYW)plane LEX - EYW
10h 46m$189–821Drive to Louisville International Airport, fly to Miami International Airport, shuttle
- Drive from Lexington to Louisville-Airport-SDFcar
- Fly from Louisville International Airport (SDF) to Miami International Airport (MIA)plane SDF - MIA
- Take a shuttle bus from Miami, FL - International Airport to Big Pine Key, FL
9h 36m$386–705Fly Blue Grass Airport to Fort Lauderdale–Hollywood International Airport, shuttle
- Fly from Blue Grass Airport (LEX) to Fort Lauderdale–Hollywood International Airport (FLL)plane LEX - FLL
- Take a shuttle bus from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
11h 27m$229–606
Lexington to Florida Keys by bus and foot (Greyhound)
Questions & Answers
The cheapest way to get from Lexington to Florida Keys is to bus which costs $130 - $370 and takes 31h 9m.
The fastest way to get from Lexington to Florida Keys is to drive and fly which takes 8h 26m and costs $190 - $800.
No, there is no direct bus from Lexington to Florida Keys. However, there are services departing from Tates Creek @ Dove Run and arriving at Sugarloaf Key - Lower - Sugarloaf Lodge via Transit Center, Lexington Bus Stop, Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 31h 9m.
The distance between Lexington and Florida Keys is 1077 miles. The road distance is 1147 miles.
The best way to get from Lexington to Florida Keys without a car is to bus which takes 31h 9m and costs $130 - $370.
It takes approximately 8h 26m to get from Lexington to Florida Keys, including transfers.
Lexington to Florida Keys bus services, operated by Greyhound USA, depart from Lexington Bus Stop station.
The best way to get from Lexington to Florida Keys is to bus which takes 31h 9m and costs $130 - $370. Alternatively, you can fly, which costs $180 - $850 and takes 10h 46m.
Lexington to Florida Keys bus services, operated by Greyhound USA, arrive at Atlanta Bus Station.
Yes, the driving distance between Lexington to Florida Keys is 1147 miles. It takes approximately 20h 25m to drive from Lexington to Florida Keys.
What companies run services between Lexington, KY, USA and Florida Keys, FL, USA?
You can take a bus from Tates Creek @ Dove Run to Florida Keys via Transit Center, Walmart @ Northpark, Lexington Bus Stop, Atlanta Bus Station, Miami Airport Station, Big Pine Key, Big Pine Key - CVS / MM30, and Sugarloaf Key - Lower - Sugarloaf Lodge in around 31h 9m. Alternatively, American Airlines, Delta, and United Airlines fly from Blue Grass Airport (LEX) to Key West International Airport (EYW) every 3 hours.
- Website
- aa.com
Flights from Louisville International Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 4h 54m
- When
- Monday, Friday, Saturday, and Sunday
- Estimated price
- $140–700
Flights from Blue Grass Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $150–750
Flights from Blue Grass Airport to Key West International Airport via Miami International Airport
- Ave. Duration
- 5h
- When
- Saturday
- Estimated price
- $150–750
Flights from Blue Grass Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 7h 18m
- When
- Monday to Saturday
- Estimated price
- $200–950
Flights from Louisville International Airport to Miami International Airport
- Ave. Duration
- 2h 43m
- When
- Every day
- Estimated price
- $100–550
Flights from Blue Grass Airport to Fort Lauderdale–Hollywood International Airport via Charlotte
- Ave. Duration
- 4h 57m
- When
- Monday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $80–410
- Website
- delta.com
Flights from Louisville International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $130–700
Flights from Blue Grass Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 36m
- When
- Every day
- Estimated price
- $140–750
Flights from Blue Grass Airport to Fort Lauderdale–Hollywood International Airport via Atlanta
- Ave. Duration
- 5h 18m
- When
- Every day
- Estimated price
- $80–410
Flights from Blue Grass Airport to Fort Lauderdale–Hollywood International Airport via Detroit
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $110–500
- Website
- southwest.com
Flights from Louisville International Airport to Miami International Airport via Orlando
- Ave. Duration
- 4h 7m
- When
- Monday
- Estimated price
- $100–550
Flights from Louisville International Airport to Miami International Airport via Nashville
- Ave. Duration
- 4h 10m
- When
- Saturday
- Estimated price
- $100–550
- Website
- allegiantair.com
Flights from Louisville International Airport to Key West International Airport via St. Petersburg
- Ave. Duration
- 4h 5m
- When
- Monday and Friday
- Estimated price
- $130–700
Flights from Blue Grass Airport to Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 2h 29m
- When
- Thursday and Sunday
- Estimated price
- $75–400
- Website
- united.com
Flights from Blue Grass Airport to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 6h 35m
- When
- Monday, Tuesday, Thursday, Saturday, and Sunday
- Estimated price
- $200–950
- Website
- spirit.com
Flights from Louisville International Airport to Key West International Airport via Fort Lauderdale–Hollywood International Airport
- Ave. Duration
- 4h 20m
- When
- Thursday
- Estimated price
- $130–700
- Website
- flybreeze.com
Flights from Louisville International Airport to Key West International Airport via Orlando
- Ave. Duration
- 4h 41m
- When
- Monday
- Estimated price
- $140–700
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Lexington Bus Stop to Atlanta Bus Station
- Ave. Duration
- 7h 50m
- Frequency
- Once daily
- Estimated price
- $50–110
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 14h 5m
- Frequency
- Once daily
- Estimated price
- $65–210
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $21–40
- Website
- https://www.greyhound.com/
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h
- Frequency
- 4 times a day
- Estimated price
- $130–180
- Website
- https://www.keysshuttle.com
Shuttle from Fort Lauderdale, FL - International Airport to Big Pine Key, FL
- Ave. Duration
- 3h 30m
- Frequency
- 4 times a day
- Estimated price
- $150–200
- Website
- https://www.keysshuttle.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
There are 803+ hotels available in Florida Keys.



