There are 8 ways to get from Lexington to Ames by car, plane, shuttle, bus, or taxi
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Covington, fly to Des Moines, shuttle
best- Drive from Lexington to Covington (CVG)car
- Fly from Covington (CVG) to Des Moines (DSM)plane CVG - DSM
- Take a shuttle bus from Des Moines International Airport, IA to Ames, IA - Iowa State University
6h 14m$185–762Fly Blue Grass Airport to Waterloo Municipal Airport, drive
cheapest- Fly from Blue Grass Airport (LEX) to Waterloo Municipal Airport (ALO)plane LEX - ALO
- Drive from Waterloo Municipal Airport (ALO) to Amescar
9h 54m$109–578Drive, bus
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY to Indianapolis Union Stationbus
- Take the bus from Indianapolis Union Station to Kansas City Bus Stationbus
- Take the bus from Kansas City to Des Moinesbus
- Take the bus from Des Moines to Amesbus
23h 9m$137–358Drive 659.8 mi
- Drive from Lexington to Amescar 659.8 mi
11h 49m$121–174Drive to Louisville International Airport, fly to Des Moines, shuttle
- Drive from Lexington to Louisville-Airport-SDFcar
- Fly from Louisville International Airport (SDF) to Des Moines (DSM)plane SDF - DSM
- Take a shuttle bus from Des Moines International Airport, IA to Ames, IA - Iowa State University
6h 45m$169–661Fly Blue Grass Airport to Des Moines, shuttle
- Fly from Blue Grass Airport (LEX) to Des Moines (DSM)plane LEX - DSM
- Take a shuttle bus from Des Moines International Airport, IA to Ames, IA - Iowa State University
8h 41m$177–742Fly Blue Grass Airport to Fort Dodge Municipal Airport, taxi
- Fly from Blue Grass Airport (LEX) to Fort Dodge Municipal Airport (FOD)plane LEX - FOD
- Take the taxi from Fort Dodge Municipal Airport (FOD) to Amestaxi
8h 57m$237–782Drive, bus via Cleveland
- Drive from Lexington to Middletown Station @ Targetcar
- Take the bus from Louisville, KY Bus Station to Cleveland Ohio Greyhound Stationbus
- Take the bus from Cleveland Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Des Moinesbus
- Take the bus from Des Moines to Amesbus
30h 39m$137–338
Covington (CVG) to Des Moines (DSM) flights
Questions & Answers
The cheapest way to get from Lexington to Ames is to drive which costs $120 - $180 and takes 11h 49m.
The fastest way to get from Lexington to Ames is to drive and fly and shuttle which takes 6h 14m and costs $180 - $800.
The distance between Lexington and Ames is 630 miles. The road distance is 663.7 miles.
It takes approximately 6h 14m to get from Lexington to Ames, including transfers.
Ames is 1h behind Lexington. It is currently 2:38 PM in Lexington and 1:38 PM in Ames.
Yes, the driving distance between Lexington to Ames is 664 miles. It takes approximately 11h 49m to drive from Lexington to Ames.
There are 53+ hotels available in Ames.
What companies run services between Lexington, KY, USA and Ames, IA, USA?
There is no direct connection from Lexington to Ames. However, you can drive to Covington (CVG) airport, fly to Des Moines (DSM), walk to Des Moines International Airport, IA, then take the shuttle to Ames, IA - Iowa State University. Alternatively, you can take a vehicle from Lexington to Ames via Middletown Station @ Target, S 5th @ W Jefferson, W Jefferson @ S 6th, W Broadway @ S 10th, Louisville, KY, Indianapolis Union Station, Kansas City, and Des Moines in around 23h 9m.
- Website
- aa.com
Flights from Covington to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 8m
- When
- Every day
- Estimated price
- $90–550
Flights from Louisville International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 6h 23m
- When
- Every day
- Estimated price
- $75–450
Flights from Blue Grass Airport to Des Moines via Dallas/Ft.Worth
- Ave. Duration
- 6h 45m
- When
- Every day
- Estimated price
- $160–800
Flights from Blue Grass Airport to Des Moines via Charlotte
- Ave. Duration
- 6h 33m
- When
- Every day
- Estimated price
- $130–700
Flights from Blue Grass Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 7h 49m
- When
- Every day
- Estimated price
- $95–550
Flights from Blue Grass Airport to Waterloo Municipal Airport via Chicago O'Hare
- Ave. Duration
- 7h 4m
- When
- Every day
- Estimated price
- $90–550
Flights from Blue Grass Airport to Waterloo Municipal Airport via Charlotte, Chicago O'Hare
- Ave. Duration
- 9h 16m
- When
- Every day
- Estimated price
- $140–700
- Website
- delta.com
Flights from Covington to Des Moines via Detroit
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $100–600
Flights from Covington to Des Moines via Minneapolis
- Ave. Duration
- 5h 28m
- When
- Every day
- Estimated price
- $110–650
Flights from Covington to Des Moines via Atlanta
- Ave. Duration
- 6h 6m
- When
- Every day
- Estimated price
- $140–750
Flights from Louisville International Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 10m
- When
- Every day
- Estimated price
- $110–600
Flights from Louisville International Airport to Des Moines via Minneapolis
- Ave. Duration
- 5h 19m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–550
Flights from Louisville International Airport to Des Moines via Detroit
- Ave. Duration
- 7h 24m
- When
- Every day
- Estimated price
- $95–550
Flights from Blue Grass Airport to Des Moines via Atlanta
- Ave. Duration
- 5h 42m
- When
- Every day
- Estimated price
- $130–700
Flights from Blue Grass Airport to Des Moines via Detroit
- Ave. Duration
- 7h 24m
- When
- Every day
- Estimated price
- $110–650
Flights from Blue Grass Airport to Des Moines via Minneapolis
- Ave. Duration
- 7h 57m
- When
- Saturday
- Estimated price
- $110–650
- Website
- united.com
Flights from Covington to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 32m
- When
- Every day
- Estimated price
- $90–550
Flights from Louisville International Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $75–450
Flights from Blue Grass Airport to Des Moines via Chicago O'Hare
- Ave. Duration
- 4h 55m
- When
- Every day
- Estimated price
- $95–550
Flights from Blue Grass Airport to Fort Dodge Municipal Airport via Chicago O'Hare
- Ave. Duration
- 4h 44m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $95–600
- Website
- southwest.com
Flights from Covington to Des Moines via Chicago Midway
- Ave. Duration
- 3h 37m
- When
- Every day
- Estimated price
- $90–550
Flights from Louisville International Airport to Des Moines via Chicago Midway
- Ave. Duration
- 4h 35m
- When
- Tuesday, Wednesday, Saturday, and Sunday
- Estimated price
- $75–450
- Phone
- +1 320.253.2226
- Website
- executiveexpress.biz
Shuttle from Des Moines International Airport, IA to Ames, IA - Iowa State University
- Ave. Duration
- 45 min
- Frequency
- On demand
- Estimated price
- $80–190
- Website
- https://www.executiveexpress.biz
- Schedules at
- https://www.executiveexpress.biz/coverage-areas/
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Indianapolis Union Station to Kansas City Bus Station
- Ave. Duration
- 10h 20m
- Frequency
- Twice a week
- Estimated price
- $80–160
- Website
- https://www.greyhound.com/
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 40m
- Frequency
- Twice daily
- Estimated price
- $60–110
- Website
- https://www.greyhound.com/
Bus from Chicago Bus Station to Des Moines
- Ave. Duration
- 8h 25m
- Frequency
- Once daily
- Estimated price
- $55–110
- Website
- https://www.greyhound.com/
- Phone
- +1-858-800-8898
- Website
- jeffersonlines.com
Bus from Kansas City to Des Moines
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $18–90
- Book at
- https://www.jeffersonlines.com
Bus from Des Moines to Ames
- Ave. Duration
- 40 min
- Frequency
- Twice daily
- Estimated price
- $3–40
- Book at
- https://www.jeffersonlines.com
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Louisville, KY Bus Station to Cleveland Ohio Greyhound Station
- Ave. Duration
- 7h 5m
- Frequency
- Once daily
- Estimated price
- $35–85
- Website
- https://baronsbus.com
Bus from Cleveland Bus Station to Chicago Bus Station
- Ave. Duration
- 7h 35m
- Frequency
- Once daily
- Estimated price
- $30–80
- Website
- https://baronsbus.com
- Ave. Duration
- 1h 21m
- Estimated price
- $140–180
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide










