There are 6 ways to get from Lawrence to Chicago by car, plane, train (Amtrak), bus (Greyhound, Flixbus), or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Drive to Manhattan Regional Airport, fly to Chicago O'Hare International Airport
best- Drive from Lawrence to Manhattan Regional Airport (MHK)
- Fly from Manhattan Regional Airport (MHK) to Chicago O'Hare International Airport (ORD)MHK - ORD
4h 14m$63–298Train (Amtrak)
- Take the train from Lawrence Amtrak Station to Chicago Union StationSouthwest Chief
9h 48m$80–200Bus
- Take the bus from Lawrence Bus Stop to St Louis Bus StationGreyhound US0136
- Take the bus from St Louis Bus Station to Chicago Bus StationFlixBus N2521 / ...
12h 5m$80–243Drive 541.3 mi
- Drive from Lawrence to Chicago541.3 mi
9h 16m$99–143Bus to Kansas City, fly to Chicago Midway International Airport
- Take the bus from Lawrence Bus Stop to Kansas City Bus Station
- Fly from Kansas City (MCI) to Chicago Midway International Airport (MDW)MCI - MDW
5h 15m$86–492Bus to Kansas City, fly to Chicago O'Hare International Airport
- Take the bus from Lawrence Bus Stop to Kansas City Bus Station
- Fly from Kansas City (MCI) to Chicago O'Hare International Airport (ORD)MCI - ORD
5h 45m$151–622
Lawrence to Chicago by train (Amtrak)
Questions & Answers
The cheapest way to get from Lawrence to Chicago is to drive which costs $95 - $150 and takes 9h 16m.
The fastest way to get from Lawrence to Chicago is to drive and fly which takes 4h 14m and costs $60 - $300.
No, there is no direct bus from Lawrence to Chicago station. However, there are services departing from Lawrence Bus Stop and arriving at Chicago Bus Station via St Louis Bus Station. The journey, including transfers, takes approximately 12h 5m.
Yes, there is a direct train departing from Lawrence Amtrak Station station and arriving at Chicago Union Station station. Services depart once daily, and operate every day. The journey takes approximately 9h 48m.
The distance between Lawrence and Chicago is 610 miles. The road distance is 544.5 miles.
The best way to get from Lawrence to Chicago without a car is to train which takes 9h 48m and costs $80 - $200.
It takes approximately 4h 14m to get from Lawrence to Chicago, including transfers.
Lawrence to Chicago bus services, operated by Greyhound USA, depart from Lawrence Bus Stop station.
Lawrence to Chicago train services, operated by Amtrak, depart from Lawrence Amtrak Station.
The best way to get from Lawrence to Chicago is to train which takes 9h 48m and costs $80 - $200. Alternatively, you can bus, which costs $80 - $250 and takes 12h 5m.
What companies run services between Lawrence, KS, USA and Chicago, IL, USA?
Amtrak operates a train from Lawrence Amtrak Station to Chicago Union Station once daily. Tickets cost $80–200 and the journey takes 9h 48m. Alternatively, you can take a bus from Lawrence Bus Stop to Chicago Bus Station via St Louis Bus Station in around 12h 5m.
- Website
- southwest.com
Flights from Kansas City to Chicago Midway International Airport
- Ave. Duration
- 1h 23m
- When
- Every day
- Estimated price
- $75–470
Flights from Kansas City to Chicago Midway International Airport via St. Louis
- Ave. Duration
- 3h 18m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $85–490
Flights from Kansas City to Chicago Midway International Airport via Indianapolis
- Ave. Duration
- 3h 35m
- When
- Wednesday and Thursday
- Estimated price
- $95–550
- Website
- aa.com
Flights from Manhattan Regional Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 56m
- When
- Every day
- Estimated price
- $45–270
Flights from Kansas City to Chicago O'Hare International Airport
- Ave. Duration
- 1h 46m
- When
- Every day
- Estimated price
- $55–350
- Website
- united.com
Flights from Kansas City to Chicago O'Hare International Airport
- Ave. Duration
- 1h 51m
- When
- Every day
- Estimated price
- $55–350
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Lawrence Amtrak Station to Chicago Union Station
- Ave. Duration
- 9h 48m
- Frequency
- Once daily
- Estimated price
- $80–200
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Lawrence Bus Stop to St Louis Bus Station
- Ave. Duration
- 4h 50m
- Frequency
- Once daily
- Estimated price
- $45–180
- Website
- https://www.greyhound.com/
Bus from Lawrence Bus Stop to Kansas City Bus Station
- Ave. Duration
- 35 min
- Frequency
- 3 times a day
- Estimated price
- $9–17
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from St Louis Bus Station to Chicago Bus Station
- Ave. Duration
- 6h 15m
- Frequency
- 3 times a day
- Estimated price
- $35–70
- Schedules at
- flixbus.com
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide
Why you should take the train in the US
Read the travel guide
Need to know: Greyhound
Read the travel guide
More Questions & Answers
Lawrence to Chicago bus services, operated by Greyhound USA, arrive at St Louis Bus Station.
Lawrence to Chicago train services, operated by Amtrak, arrive at Chicago Union Station.
Yes, the driving distance between Lawrence to Chicago is 544 miles. It takes approximately 9h 16m to drive from Lawrence to Chicago.
Book your Lawrence to Chicago train tickets online with Omio.
Book your Lawrence to Chicago bus tickets online with Omio and FlixBus.
There are 1245+ hotels available in Chicago.