There are 6 ways to get from Larissa to Istanbul by train, plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Train to Thessaloniki, fly  •  6 h 31 min

  1. Take the train from Λάρισα to Θεσσαλονίκη
  2. Fly from Thessaloniki (SKG) to Istanbul (IST) SKG - IST

$89 - $227

Cheapest option

Bus Kamil Koc  •  12 h 24 min

  1. Take the bus from Larissa to Istanbul Otogar

$15 - $43

4 alternative options

Train to Athens, fly  •  9 h 1 min

  1. Take the train from Λάρισα to Σκα
  2. Fly from Athens (ATH) to Istanbul (IST) ATH - IST

$83 - $240

Bus Alpar Turizm  •  13 h 57 min

  1. Take the bus from Larissa to Thessaloniki
  2. Take the bus from Thessaloniki to Xánthi
  3. Take the bus from Xanthi to Istanbul

$24 - $38

Train  •  17 h 55 min

  1. Take the train from Λάρισα to Θεσσαλονίκη
  2. Take the train from Θεσσαλονίκη to Αλεξανδρούπολη Λιμάνι
  3. Take the train from Αλεξανδρούπολη Λιμάνι to Πύθιο Διδυμοτείχου
  4. Take the train from Bahçıvanova to Halkali

$68 - $96

Drive  •  8 h 16 min

  1. Drive from Larissa to Istanbul 463.4 miles

$110 - $170

Questions & Answers

The cheapest way to get from Larissa to Istanbul is to bus which costs 20€ - 35€ and takes 13 h 57 min.

More details

The quickest way to get from Larissa to Istanbul is to train and fly which costs 75€ - 200€ and takes 6 h 31 min.

More details

The distance between Larissa and Istanbul is 574 km. The road distance is 741.4 km.

Get driving directions

It takes approximately 6 h 31 min to get from Larissa to Istanbul, including transfers.

More details

What companies run services between Larissa, Greece and Istanbul, Turkey?

Kamil Koc operates a bus from Larissa to Istanbul once daily. Tickets cost $14 - $45 and the journey takes 12 h 10 min. Crazy Holidays also services this route once a week. Alternatively, you can take a train from Larissa to Istanbul via Θεσσαλονίκη, Αλεξανδρούπολη Λιμάνι, Πύθιο Διδυμοτείχου, Bahçıvanova, and Halkali in around 17 h 55 min.

Airlines
Aegean Airlines
Website
aegeanair.com
Flights from Thessaloniki to Istanbul
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$100 - $310
Flights from Thessaloniki to Istanbul via Athens
Ave. Duration
3 h 26 min
When
Every day
Estimated price
$90 - $310
Flights from Athens to Istanbul
Ave. Duration
1 h 26 min
When
Every day
Estimated price
$70 - $290
Flights from Athens to Istanbul via Thessaloniki
Ave. Duration
3 h 25 min
When
Every day
Estimated price
$90 - $310
Turkish Airlines
Website
p.turkishairlines.com
Flights from Thessaloniki to Istanbul
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$100 - $310
Flights from Athens to Istanbul
Ave. Duration
1 h 26 min
When
Every day
Estimated price
$70 - $290
Train operators
Greek Railways (OSE)
Website
trainose.gr
Train from Λάρισα to Θεσσαλονίκη
Ave. Duration
1 h 36 min
Frequency
Hourly
Estimated price
$10 - $13
Website
trainose.gr
Book at
Raileurope.com
Second Class
$10 - $13
First Class
$12 - $16
Train from Λάρισα to Σκα
Ave. Duration
3 h 50 min
Frequency
5 times a day
Estimated price
$18 - $25
Website
trainose.gr
Book at
Raileurope.com
Second Class
$18 - $25
First Class
$23 - $35
Train from Θεσσαλονίκη to Αλεξανδρούπολη Λιμάνι
Ave. Duration
6 h 35 min
Frequency
Twice daily
Estimated price
$24 - $35
Website
trainose.gr
Book at
Raileurope.com
Second Class
$24 - $35
First Class
$30 - $45
Train from Αλεξανδρούπολη Λιμάνι to Πύθιο Διδυμοτείχου
Ave. Duration
1 h 36 min
Frequency
Every 4 hours
Estimated price
$7 - $10
Website
trainose.gr
Book at
Raileurope.com
Second Class
$7 - $10
First Class
$9 - $12
Turkish Railways (TCDD)
Phone
+90 444 8 233
Website
tcddtasimacilik.gov.tr
Train from Bahçıvanova to Halkali
Ave. Duration
3 h 39 min
Frequency
Once daily
Estimated price
$3 - $5
Website
tcdd.gov.tr
Bus operators
Crazy Holidays
Phone
2310-241545
Website
crazyholidays.gr
Bus from Larissa to Istanbul Otogar
Ave. Duration
10 h
Frequency
Once a week
Estimated price
$55 - $80
Schedules at
crazyholidays.gr
KTEL Larisas
Phone
2410 567.600
Website
ktellarisas.gr
Bus from Larissa to Thessaloniki
Ave. Duration
2 h 15 min
Frequency
Hourly
Schedules at
ktellarisas.gr
KTEL Xanthis
Phone
25410 27200
Email
info@ktelxanthis.gr
Website
ktelxanthis.gr
Bus from Thessaloniki to Xánthi
Ave. Duration
3 h 30 min
Frequency
Every 3 hours
Schedules at
ktelxanthis.gr
Alpar Turizm
Phone
0090 212 658 18 51
Email
info@alparturizm.com.tr
Website
alparturizm.com.tr
Bus from Xanthi to Istanbul
Ave. Duration
5 h 58 min
Frequency
Once daily
Estimated price
$22 - $40
Schedules at
alparturizm.com.tr

Want to know more about travelling around Turkey

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.