There are 10 ways to get from Lady Lake to Key West by shuttle, plane, bus, ferry, car, taxi, train, or bus (Greyhound)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle to Orlando, fly
best- Take a shuttle bus from Lake Sumter Depot to MCO Airport - Terminal A
- Fly from Orlando (MCO) to Key West International Airport (EYW)plane MCO - EYW
4h 8m$146–426Drive, train, bus
cheapest- Drive from Lady Lake to Orlandocar
- Take the train from Orlando to Miamitrain
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
12h 7m$51–286Bus, ferry
- Take the bus from Wildwood to Fort Myersbus Houston
- Take the ferry from Fort Myers Beach, FL to Key West, FLferry Fort Myers Beach
10h 12m$249–289Drive 414.7 mi
- Drive from Lady Lake to Key Westcar 414.7 mi
8h 29m$76–110Shuttle, bus
- Take a shuttle bus from Spanish Springs to MCO Airport - Terminal A
- Take the bus from Orlando to Miami Airport Stationbus
- Take a shuttle bus from Miami, FL - International Airport to Key West, FL
14h 19m$229–330Shuttle to Tampa, fly
- Take a shuttle bus from Lake Sumter Depot to Tampa International Airport - Red Terminal
- Fly from Tampa (TPA) to Key West International Airport (EYW)plane TPA - EYW
4h 58m$176–471Taxi to Orlando Sanford, fly
- Take the taxi from Lady Lake to Orlando-Sanford-Airport-SFBtaxi
- Fly from Orlando Sanford (SFB) to Key West International Airport (EYW)plane SFB - EYW
2h 35m$189–552Taxi to Daytona Beach International Airport, fly
- Take the taxi from Lady Lake to Amelia Super Stoptaxi
- Fly from Daytona Beach International Airport (DAB) to Key West International Airport (EYW)plane DAB - EYW
7h 6m$558–900Bus to Gainesville Regional Airport, fly
- Take the bus from Ocala to Gainesville - Commuter Lot Parking Garage @ Gale Lemerandbus
- Fly from Gainesville Regional Airport (GNV) to Key West International Airport (EYW)plane GNV - EYW
8h 57m$164–671Bus
- Take the bus from Ocala to Miami Airportbus
- Take the bus from Miami Airport Station to Big Pine Keybus
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Streetbus Lks
13h 22m$116–255
Orlando (MCO) to Key West International Airport (EYW) flights
Questions & Answers
The cheapest way to get from Lady Lake to Key West is to drive which costs $75 - $110 and takes 8h 29m.
The fastest way to get from Lady Lake to Key West is to taxi and fly which takes 2h 35m and costs $180 - $550.
The distance between Lady Lake and Key West is 345 miles. The road distance is 417.1 miles.
The best way to get from Lady Lake to Key West without a car is to bus and ferry which takes 10h 12m and costs $240 - $290.
It takes approximately 4h 8m to get from Lady Lake to Key West, including transfers.
Yes, the driving distance between Lady Lake to Key West is 417 miles. It takes approximately 8h 29m to drive from Lady Lake to Key West.
There are 734+ hotels available in Key West.
What companies run services between Lady Lake, FL, USA and Key West, FL, USA?
You can take a vehicle from Lady Lake to N Roosevelt & 3rd Street via Ocala, Miami Airport, Miami International Airport, Miami, Airport Intermodal Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 13h 22m.
- Website
- aa.com
Flights from Orlando to Key West International Airport via Miami
- Ave. Duration
- 3h 32m
- When
- Every day
- Estimated price
- $50–340
Flights from Tampa to Key West International Airport via Miami
- Ave. Duration
- 3h 7m
- When
- Saturday
- Estimated price
- $55–370
Flights from Daytona Beach International Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 54m
- When
- Every day
- Estimated price
- $160–850
Flights from Gainesville Regional Airport to Key West International Airport via Miami
- Ave. Duration
- 4h 56m
- When
- Every day
- Estimated price
- $65–440
Flights from Gainesville Regional Airport to Key West International Airport via Charlotte
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $120–600
Flights from Gainesville Regional Airport to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 6m
- When
- Every day
- Estimated price
- $180–800
- Website
- delta.com
Flights from Daytona Beach International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 6m
- When
- Every day
- Estimated price
- $150–800
Flights from Gainesville Regional Airport to Key West International Airport via Atlanta
- Ave. Duration
- 6h 9m
- When
- Every day
- Estimated price
- $100–600
- Website
- flybreeze.com
Flights from Orlando to Key West International Airport
- Ave. Duration
- 1h 16m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $70–470
Flights from Tampa to Key West International Airport
- Ave. Duration
- 1h 9m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $110–320
- Website
- spirit.com
Flights from Tampa to Key West International Airport via Fort Lauderdale
- Ave. Duration
- 3h 18m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $85–380
- Website
- allegiantair.com
Flights from Orlando Sanford to Key West International Airport
- Ave. Duration
- 1h 20m
- When
- Thursday and Sunday
- Estimated price
- $60–400
- Phone
- +1 831-539-2901
- guestservices@gobrightline.com
- Website
- gobrightline.com
Train from Orlando to Miami
- Ave. Duration
- 3h 34m
- Frequency
- Every 3 hours
- Estimated price
- $15–230
- Book at
- https://www.gobrightline.com
- Smart
- $15–200
- Premium
- $65–230
- Phone
- +1 352 539 9664
- Website
- groometransportation.com
Shuttle from Lake Sumter Depot to MCO Airport - Terminal A
- Ave. Duration
- 1h 40m
- Frequency
- Hourly
- Estimated price
- $35–55
- Website
- https://groometransportation.com/the-villages/?&sd_client_id=992f7c93-d719-43a2-9d9e-8c8cbbd08d74
- online discount
- $35–50
- call in
- $40–55
Shuttle from Spanish Springs to MCO Airport - Terminal A
- Ave. Duration
- 2h 10m
- Frequency
- Hourly
- Estimated price
- $35–55
- Website
- https://groometransportation.com/the-villages/?&sd_client_id=992f7c93-d719-43a2-9d9e-8c8cbbd08d74
- online discount
- $35–50
- call in
- $40–55
Shuttle from Lake Sumter Depot to Tampa International Airport - Red Terminal
- Ave. Duration
- 2h 30m
- Frequency
- Hourly
- Estimated price
- $50–70
- Website
- https://groometransportation.com/the-villages/?&sd_client_id=992f7c93-d719-43a2-9d9e-8c8cbbd08d74
- online discount
- $50–65
- call in
- $55–70
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Wildwood to Fort Myers
- Ave. Duration
- 4h 29m
- Frequency
- Once daily
- Estimated price
- $60–80
- Schedules at
- omnibusexpress.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Orlando to Miami Airport Station
- Ave. Duration
- 4h 15m
- Frequency
- Every 4 hours
- Estimated price
- $28–55
- Schedules at
- flixbus.com
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Miami, FL - International Airport to Key West, FL
- Ave. Duration
- 4h
- Frequency
- 4 times a day
- Estimated price
- $150–200
- Website
- https://www.keysshuttle.com
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Ocala to Gainesville - Commuter Lot Parking Garage @ Gale Lemerand
- Ave. Duration
- 55 min
- Frequency
- 3 times a day
- Estimated price
- $21–140
- Website
- https://www.redcoachusa.com
- Web
- $21–140
Bus from Ocala to Miami Airport
- Ave. Duration
- 6h
- Frequency
- 4 times a day
- Estimated price
- $26–140
- Website
- https://www.redcoachusa.com
- Web
- $26–140
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $23–35
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
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