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There are 8 ways to get from La Serena to Tupiza by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus Turbus, train  •  32 h 51 min

  1. Take the bus from Serena to Calama
  2. Take the bus from Calama to Ollagüe
  3. Take the train from Avaroa to Uyuní
  4. Take the train from Uyuní to Tupiza

$37 - $80

7 alternative options

Bus Pluss Chile, train  •  33 h 29 min

  1. Take the bus from La Serena to Calama
  2. Take the bus from Calama to Uyuni
  3. Take the train from Uyuní to Tupiza

$46 - $107

Bus  •  34 h 19 min

  1. Take the bus from La Serena to Calama
  2. Take the bus from Calama to Uyuni
  3. Take the bus from Uyuni to Tupiza

$67 - $89

Drive  •  22 h 38 min

  1. Drive from La Serena to Tupiza 1111.9 miles

$180 - $270

Fly to Uyuni, train  •  19 h 53 min

  1. Fly from La Serena (LSC) to Uyuni (UYU) LSC - UYU
  2. Take the train from Uyuní to Tupiza

$164 - $826

Fly to Calama, bus, train  •  21 h 41 min

  1. Fly from La Serena (LSC) to Calama (CJC) LSC - CJC
  2. Take the bus from Calama to Uyuni
  3. Take the train from Uyuní to Tupiza

$135 - $1,063

Fly to Tarija, bus  •  24 h 1 min

  1. Fly from La Serena (LSC) to Tarija (TJA) LSC - TJA
  2. Take the bus from Tarija to Tupiza

$196 - $762

Fly to Salta, bus, train  •  23 h 1 min

  1. Fly from La Serena (LSC) to Salta (SLA) LSC - SLA
  2. Take the bus from Salta to San Salvador de Jujuy
  3. Take the bus from San Salvador de Jujuy to Humahuaca
  4. Take the bus from Humahuaca to La Quiaca
  5. Take the train from Villazón to Tupiza

Questions & Answers

The cheapest way to get from La Serena to Tupiza is to bus and train which costs $35 - $80 and takes 32 h 51 min.

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The quickest way to get from La Serena to Tupiza is to fly and train which costs $160 - $850 and takes 19 h 53 min.

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No, there is no direct bus from La Serena to Tupiza. However, there are services departing from La Serena and arriving at Tupiza via Calama and Uyuni. The journey, including transfers, takes approximately 34 h 19 min.

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The distance between La Serena and Tupiza is 1091 km. The road distance is 1779 km.

Get driving directions

The best way to get from La Serena to Tupiza without a car is to bus and train which takes 33 h 29 min and costs $45 - $110.

More details

It takes approximately 32 h 51 min to get from La Serena to Tupiza, including transfers.

More details

La Serena to Tupiza bus services, operated by Ciktur, depart from La Serena station.

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There is no direct flight from La Serena Airport to Uyuni Airport. The quickest flight takes 16 h 36 min and has two stopovers.

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La Serena to Tupiza bus services, operated by Predilecto Tours, arrive at Tupiza station.

More details

Tupiza is 1 h behind La Serena. It is currently 8:36 PM in La Serena and 7:36 PM in Tupiza.

Map of how to get from La Serena to Tupiza.
Launch map view
  • Distance: 682.2 miles
  • Duration: 32 h 51 min

What companies run services between La Serena, Chile and Tupiza, Bolivia?

You can take a bus from La Serena to Tupiza via Calama, Calama, Uyuni, and Uyuni in around 34 h 19 min.

Airlines
Boliviana de Aviación
Website
boa.bo
Flights from La Serena to Uyuni via Iquique, La Paz
Ave. Duration
11 h 32 min
When
Monday, Wednesday and Friday
Estimated price
$150 - $800
Flights from La Serena to Tarija via Santiago, Santa Cruz, Cochabamba
Ave. Duration
14 h 50 min
When
Tuesday
Estimated price
$200 - $800
Flights from La Serena to Tarija via Santiago, La Paz
Ave. Duration
20 h 8 min
When
Monday, Wednesday, Thursday and Sunday
Estimated price
$200 - $800
Flights from La Serena to Tarija via Santiago, Santa Cruz, Sucre
Ave. Duration
17 h 55 min
When
Tuesday
Estimated price
$190 - $800
Flights from La Serena to Tarija via Santiago, La Paz, Sucre
Ave. Duration
18 h 8 min
When
Monday, Thursday and Sunday
Estimated price
$200 - $800
Flights from La Serena to Tarija via Santiago, Santa Cruz, La Paz
Ave. Duration
19 h 55 min
When
Tuesday
Estimated price
$220 - $850
Flights from La Serena to Tarija via Santiago, Santa Cruz
Ave. Duration
23 h 20 min
When
Tuesday
Estimated price
$190 - $750
Flights from La Serena to Tarija via Antofagasta, Santiago, La Paz
Ave. Duration
21 h 44 min
When
Thursday
Estimated price
$250 - $900
Amaszonas
Website
amaszonas.com
Flights from La Serena to Uyuni via Iquique, La Paz
Ave. Duration
11 h 22 min
When
Monday, Wednesday and Friday
Estimated price
$150 - $800
Flights from La Serena to Uyuni via Santiago, Iquique, La Paz
Ave. Duration
10 h 36 min
When
Monday and Tuesday
Estimated price
$430 - $1,700
Flights from La Serena to Uyuni via Santiago, Santa Cruz
Ave. Duration
15 h 40 min
When
Tuesday
Estimated price
$430 - $1,700
Flights from La Serena to Uyuni via Santiago, Lima, La Paz
Ave. Duration
15 h 18 min
When
Sunday
Estimated price
$550 - $2,000
Flights from La Serena to Uyuni via Antofagasta, Santiago, Santa Cruz
Ave. Duration
17 h 29 min
When
Thursday
Estimated price
$550 - $1,900
Flights from La Serena to Uyuni via Calama, Santiago, Santa Cruz
Ave. Duration
18 h 44 min
When
Thursday
Estimated price
$550 - $2,000
LATAM Chile
Website
latam.com
Flights from La Serena to Calama
Ave. Duration
1 h 24 min
When
Thursday and Friday
Estimated price
$110 - $1,000
Flights from La Serena to Salta via Santiago, Iquique
Ave. Duration
14 h 27 min
When
Friday
Estimated price
$190 - $850
Flights from La Serena to Salta via Santiago, Buenos Aires Jorge Newbery
Ave. Duration
14 h 1 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$280 - $1,100
Aerolíneas Argentinas
Website
aerolineas.com.ar
Flights from La Serena to Salta via Santiago, Buenos Aires Jorge Newbery
Ave. Duration
8 h
When
Wednesday, Saturday and Sunday
Estimated price
$380 - $1,100
Flights from La Serena to Salta via Cordoba, Buenos Aires Jorge Newbery
Ave. Duration
13 h 35 min
When
Monday
Estimated price
$370 - $1,100
Flights from La Serena to Salta via Santiago, Buenos Aires Ministro Pistarini
Ave. Duration
15 h 30 min
When
Monday
Estimated price
$380 - $1,100
JetSMART
Website
jetsmart.com
Flights from La Serena to Calama
Ave. Duration
1 h 40 min
When
Monday, Tuesday, Wednesday and Thursday
Estimated price
$55 - $380
Train operators
Empresa Ferroviaria Andina S.A
Phone
(+591-2) 2184555 / 4566
Website
fca.com.bo
Train from Avaroa to Uyuní
Ave. Duration
6 h 30 min
Frequency
On demand
Estimated price
$2 - $11
Schedules at
ferroviaria-andina.com.bo
Book at
ticketsbolivia.com.bo
Wara Wara del Sur - Popular
$2 - $4
Wara Wara del Sur - Salon
$4 - $5
Expreso del Sur - Salon
$5 - $7
Wara Wara del Sur - Ejecutivo
$8 - $11
Train from Uyuní to Tupiza
Ave. Duration
5 h 40 min
Frequency
4 times a week
Estimated price
$3 - $12
Schedules at
ferroviaria-andina.com.bo
Book at
ticketsbolivia.com.bo
Wara Wara del Sur - Popular
$3 - $4
Wara Wara del Sur - Salon
$4 - $6
Expreso del Sur - Salon
$5 - $7
Wara Wara del Sur - Ejecutivo
$9 - $12
Train from Villazón to Tupiza
Ave. Duration
2 h 45 min
Frequency
3 times a week
Estimated price
$1 - $7
Schedules at
ferroviaria-andina.com.bo
Book at
ticketsbolivia.com.bo
Wara Wara del Sur - Popular
$1 - $3
Wara Wara del Sur - Salon
$2 - $4
Expreso del Sur - Salon
$3 - $5
Wara Wara del Sur - Ejecutivo
$5 - $7
Bus operators
Turbus
Phone
+56 22 822 7500
Email
atencion_clientes@turbus.cl
Website
turbus.cl
Bus from Serena to Calama
Ave. Duration
14 h 30 min
Frequency
4 times a day
Estimated price
$24 - $50
Schedules at
turbus.cl
2nd Class
$24 - $50
Premium
$50 - $75
1st Class
$60 - $90
Cruz del Norte
Phone
+56 (9) 82248119
Email
ventas@turisticointernacionalcruzdelnorte.com
Website
turisticointernacionalcruzdelnorte.com
Bus from Calama to Ollagüe
Ave. Duration
3 h 30 min
Frequency
Twice daily
Estimated price
$7 - $9
Schedules at
turisticointernacionalcruzdelnorte.com
Book at
ticketsbolivia.com.bo
Bus from Calama to Uyuni
Ave. Duration
10 h 30 min
Frequency
Twice daily
Estimated price
$15 - $35
Schedules at
turisticointernacionalcruzdelnorte.com
Book at
ticketsbolivia.com.bo
Pluss Chile
Phone
+56 (2) 26419926
Email
info@plusschile.cl
Website
plusschile.cl
Bus from La Serena to Calama
Ave. Duration
15 h 4 min
Frequency
Every 3 hours
Estimated price
$46
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Pullman Bus
Phone
600 320 3200
Website
pullman.cl
Bus from La Serena to Calama
Ave. Duration
15 h 50 min
Frequency
Every 4 hours
Estimated price
$35 - $55
Schedules at
pullman.cl
Ciktur
Phone
951690977
Email
servicioalcliente@ciktur.cl
Website
ciktur.cl
Bus from La Serena to Calama
Ave. Duration
16 h 55 min
Frequency
Every 4 hours
Estimated price
$47
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Expreso Norte
Website
expresonorte.cl
Bus from La Serena to Calama
Ave. Duration
14 h 27 min
Frequency
Twice daily
Estimated price
$29 - $65
Schedules at
expresonorte.cl
Semi Cama
$30
Cama
$61
Atacama 2000
Phone
+ 56 55 31 6664
Bus from Calama to Uyuni
Ave. Duration
8 h 30 min
Frequency
4 times a week
Estimated price
$15
Schedules at
voyhoy.com
Book at
voyhoy.com
Predilecto Tours
Trans Tours Juarez
Phone
+591 4 6631961
Website
facebook.com
Bus from Tarija to Tupiza
Ave. Duration
6 h
Frequency
3 times a day
Estimated price
$11
Schedules at
facebook.com
Expreso Diamante
Phone
+591 71272930 / 2 6244430
Website
facebook.com
Bus from Tarija to Tupiza
Ave. Duration
6 h
Frequency
Once daily
Estimated price
$6
Schedules at
mi.lapaz.bo
Evelia
Phone
+54 (0388) 4251771
Email
tallerevelia1@hotmail.com
Website
facebook.com
Bus from San Salvador de Jujuy to Humahuaca
Ave. Duration
2 h
Frequency
Hourly
Estimated price
$4
Schedules at
es-la.facebook.com
El Quiaqueño
Phone
+54 (0388) 4280041 / 4281161
Email
elquiaqueosrl@yahoo.com.ar
Website
xn--elquiaqueo-19a.com
Bus from San Salvador de Jujuy to Humahuaca
Ave. Duration
2 h
Frequency
Every 3 hours
Schedules at
xn--elquiaqueo-19a.com
Bus from Humahuaca to La Quiaca
Ave. Duration
2 h 25 min
Frequency
Every 3 hours
Schedules at
xn--elquiaqueo-19a.com

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More Questions & Answers

Yes, the driving distance between La Serena to Tupiza is 1779 km. It takes approximately 22 h 38 min to drive from La Serena to Tupiza.

Get driving directions

Boliviana de Aviación, JetSMART, Amaszonas and LATAM Chile offer flights from La Serena Airport to Uyuni Airport.

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There are 15+ hotels available in Tupiza. Prices start at $10 USD per night.

More details

The best way to get from La Serena to La Serena Airport is to line 8113 bus which takes 24 min and costs $1.

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