There are 10 ways to get from La Serena to Tupiza by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, train  •  29 h 58 min

  1. Take the bus from Serena to Calama
  2. Take the bus from Calama to Uyuni
  3. Take the train from Uyuní to Tupiza

$38 - $102

Cheapest option

Bus, train via Avaroa  •  32 h 56 min

  1. Take the bus from Serena to Calama
  2. Take the bus from Calama to Ollagüe
  3. Take the train from Avaroa to Uyuní
  4. Take the train from Uyuní to Tupiza

$37 - $104

8 alternative options

Bus  •  30 h 49 min

  1. Take the bus from La Serena to Calama
  2. Take the bus from Calama to Uyuni
  3. Take the bus from Uyuni to Tupiza

$47 - $90

Bus, train via San Pedro de Atacama  •  38 h 2 min

  1. Take the bus from La Serena to San Pedro de Atacama
  2. Take the bus from San Pedro de Atacama to Uyuni
  3. Take the train from Uyuní to Tupiza

$48 - $122

Drive  •  22 h 38 min

  1. Drive from La Serena to Tupiza 1111.9 miles

$180 - $270

Fly to Tarija, bus  •  21 h 21 min

  1. Fly from La Serena (LSC) to Tarija (TJA) LSC - TJA
  2. Take the bus from Tarija to Tupiza

$196 - $762

Fly to Uyuni, train  •  22 h 30 min

  1. Fly from La Serena (LSC) to Uyuni (UYU) LSC - UYU
  2. Take the train from Uyuní to Tupiza

$444 - $1,726

Fly to Calama, bus, train  •  19 h 4 min

  1. Fly from La Serena (LSC) to Calama (CJC) LSC - CJC
  2. Take the bus from Calama to Uyuni
  3. Take the train from Uyuní to Tupiza

$134 - $1,041

Fly to Potosi, bus  •  20 h 54 min

  1. Fly from La Serena (LSC) to Potosi (POI) LSC - POI
  2. Take the bus from Potosí to Tupiza

$326 - $1,253

Fly to Jujuy, bus  •  19 h 41 min

  1. Fly from La Serena (LSC) to Jujuy (JUJ) LSC - JUJ
  2. Take the bus from San Salvador de Jujuy to La Quiaca
  3. Take the bus from Villazón to Tupiza

$353 - $1,017

Questions & Answers

The cheapest way to get from La Serena to Tupiza is to bus which costs $45 - $90 and takes 30 h 49 min.

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The quickest way to get from La Serena to Tupiza is to fly and bus and train which costs $130 - $1,100 and takes 19 h 4 min.

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No, there is no direct bus from La Serena to Tupiza. However, there are services departing from La Serena and arriving at Tupiza via Calama and Uyuni. The journey, including transfers, takes approximately 30 h 49 min.

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The distance between La Serena and Tupiza is 1091 km. The road distance is 1779 km.

Get driving directions

The best way to get from La Serena to Tupiza without a car is to bus and train which takes 29 h 58 min and costs $35 - $110.

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It takes approximately 29 h 58 min to get from La Serena to Tupiza, including transfers.

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La Serena to Tupiza bus services, operated by Pluss Chile, depart from La Serena station.

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There is no direct flight from La Serena Airport to Tarija Airport. The quickest flight takes 18 h 1 min and has two stopovers.

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La Serena to Tupiza bus services, operated by Predilecto Tours, arrive at Tupiza station.

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Yes, the driving distance between La Serena to Tupiza is 1779 km. It takes approximately 22 h 38 min to drive from La Serena to Tupiza.

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Map of how to get from La Serena to Tupiza.
Launch map view
  • Distance: 682.2 miles
  • Duration: 29 h 58 min

What companies run services between La Serena, Chile and Tupiza, Bolivia?

You can take a bus from La Serena to Tupiza via Calama, Calama, Uyuni, and Uyuni in around 30 h 49 min.

Airlines
Boliviana de Aviación
Website
boa.bo
Flights from La Serena to Tarija via Santiago, Santa Cruz, Cochabamba
Ave. Duration
14 h 51 min
When
Tuesday
Estimated price
$200 - $800
Flights from La Serena to Tarija via Santiago, La Paz
Ave. Duration
19 h 23 min
When
Monday
Estimated price
$200 - $800
Flights from La Serena to Tarija via Santiago, Santa Cruz, Sucre
Ave. Duration
17 h 56 min
When
Tuesday
Estimated price
$190 - $800
Flights from La Serena to Tarija via Santiago, Santa Cruz, La Paz
Ave. Duration
19 h 56 min
When
Tuesday
Estimated price
$220 - $850
Flights from La Serena to Uyuni via Santiago, Santa Cruz, La Paz
Ave. Duration
13 h 16 min
When
Tuesday
Estimated price
$470 - $1,800
Flights from La Serena to Potosi via Santiago, Santa Cruz, Cochabamba
Ave. Duration
13 h 15 min
When
Tuesday and Thursday
Estimated price
$290 - $1,200
Flights from La Serena to Potosi via Santiago, Lima, La Paz
Ave. Duration
15 h 15 min
When
Tuesday and Sunday
Estimated price
$370 - $1,300
Amaszonas
Website
amaszonas.com
Flights from La Serena to Uyuni via Santiago, Santa Cruz
Ave. Duration
14 h 26 min
When
Tuesday
Estimated price
$430 - $1,700
Flights from La Serena to Uyuni via Santiago, Lima, La Paz
Ave. Duration
16 h 5 min
When
Tuesday and Sunday
Estimated price
$550 - $2,000
Flights from La Serena to Uyuni via Calama, Santiago, Santa Cruz
Ave. Duration
17 h 51 min
When
Thursday
Estimated price
$550 - $2,000
Flights from La Serena to Uyuni via Santiago, Lima, Santa Cruz
Ave. Duration
18 h 5 min
When
Tuesday and Sunday
Estimated price
$600 - $2,100
Flights from La Serena to Uyuni via Santiago, La Paz
Ave. Duration
23 h 38 min
When
Monday
Estimated price
$430 - $1,700
Flights from La Serena to Uyuni via Santiago, Cordoba, Santa Cruz
Ave. Duration
21 h 17 min
When
Tuesday
Estimated price
$750 - $2,200
Eco Jet
Website
ecojet.bo
Flights from La Serena to Tarija via Santiago, Santa Cruz
Ave. Duration
12 h 1 min
When
Tuesday
Estimated price
$190 - $750
Flights from La Serena to Tarija via Calama, Santiago, Santa Cruz
Ave. Duration
15 h 26 min
When
Thursday
Estimated price
$250 - $900
Flights from La Serena to Tarija via Santiago, Lima, Santa Cruz
Ave. Duration
15 h 40 min
When
Tuesday and Sunday
Estimated price
$270 - $950
Aerolíneas Argentinas
Website
aerolineas.com.ar
Flights from La Serena to Jujuy via Santiago, Cordoba
Ave. Duration
7 h 3 min
When
Sunday
Estimated price
$340 - $1,000
Flights from La Serena to Jujuy via Santiago, Buenos Aires Jorge Newbery
Ave. Duration
13 h 10 min
When
Monday to Friday
Estimated price
$390 - $1,200
LATAM Chile
Website
latam.com
Flights from La Serena to Calama
Ave. Duration
1 h 27 min
When
Thursday and Friday
Estimated price
$110 - $1,000
Train operators
Empresa Ferroviaria Andina S.A
Phone
(+591-2) 2184555 / 4566
Website
fca.com.bo
Train from Uyuní to Tupiza
Ave. Duration
5 h 45 min
Frequency
4 times a week
Estimated price
$3 - $12
Schedules at
fca.com.bo
Book at
ticketsbolivia.com.bo
Wara Wara del Sur - Popular
$3 - $4
Wara Wara del Sur - Salon
$4 - $6
Expreso del Sur - Salon
$5 - $7
Wara Wara del Sur - Ejecutivo
$9 - $12
Train from Avaroa to Uyuní
Ave. Duration
6 h 30 min
Frequency
On demand
Estimated price
$2 - $11
Schedules at
fca.com.bo
Book at
ticketsbolivia.com.bo
Wara Wara del Sur - Popular
$2 - $4
Wara Wara del Sur - Salon
$4 - $5
Expreso del Sur - Salon
$5 - $7
Wara Wara del Sur - Ejecutivo
$8 - $11
Bus operators
Turbus
Phone
+56 22 822 7500
Email
atencion_clientes@turbus.cl
Website
turbus.cl
Bus from Serena to Calama
Ave. Duration
14 h 30 min
Frequency
4 times a day
Estimated price
$24 - $75
Schedules at
turbus.cl
2nd Class
$24 - $50
Premium
$50 - $75
1st Class
$60 - $90
Bus from La Serena to San Pedro de Atacama
Ave. Duration
16 h 55 min
Frequency
Twice daily
Estimated price
$25 - $75
Schedules at
turbus.cl
2nd Class
$25 - $50
Premium
$50 - $75
1st Class
$65 - $95
Atacama 2000
Phone
+ 56 55 31 6664
Bus from Calama to Uyuni
Ave. Duration
7 h 30 min
Frequency
4 times a week
Estimated price
$15
Schedules at
voyhoy.com
Book at
voyhoy.com
Pluss Chile
Phone
+56 (2) 26419926
Email
info@plusschile.cl
Website
plusschile.cl
Bus from La Serena to Calama
Ave. Duration
15 h 4 min
Frequency
Every 3 hours
Estimated price
$47
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Expreso Norte
Website
expresonorte.cl
Bus from La Serena to Calama
Ave. Duration
14 h 27 min
Frequency
Twice daily
Estimated price
$29 - $65
Schedules at
expresonorte.cl
Semi Cama
$30
Cama
$61
Pullman Bus
Phone
600 320 3200
Website
pullman.cl
Bus from La Serena to Calama
Ave. Duration
14 h 50 min
Frequency
Twice daily
Estimated price
$35 - $65
Schedules at
pullman.cl
Predilecto Tours
Cruz del Norte
Phone
+56 (9) 82248119
Email
ventas@turisticointernacionalcruzdelnorte.com
Website
turisticointernacionalcruzdelnorte.com
Bus from Calama to Ollagüe
Ave. Duration
3 h 30 min
Frequency
Once daily
Estimated price
$7 - $9
Schedules at
turisticointernacionalcruzdelnorte.com
Book at
ticketsbolivia.com.bo
Bus from San Pedro de Atacama to Uyuni
Ave. Duration
13 h
Frequency
Once daily
Estimated price
$19 - $35
Schedules at
turisticointernacionalcruzdelnorte.com
Book at
ticketsbolivia.com.bo
Trans Tours Juarez
Phone
+591 4 6631961
Website
facebook.com
Bus from Tarija to Tupiza
Ave. Duration
6 h
Frequency
3 times a day
Estimated price
$11
Schedules at
facebook.com
Expreso Diamante
Phone
+591 71272930 / 2 6244430
Website
facebook.com
Bus from Tarija to Tupiza
Ave. Duration
6 h
Frequency
Once daily
Estimated price
$6
Schedules at
mi.lapaz.bo
Bus from Potosí to Tupiza
Ave. Duration
5 h
Frequency
Once daily
Estimated price
$12
Schedules at
mi.lapaz.bo
Autotransportes Tupiza
Phone
+591 68421233 Tupiza / 3 3311649 Santa Cruz / 2 6243044 Potosí
Website
facebook.com
Bus from Potosí to Tupiza
Ave. Duration
5 h
Frequency
Every 4 hours
Estimated price
$5 - $7
Schedules at
facebook.com
Bus from Villazón to Tupiza
Ave. Duration
2 h
Frequency
Every 4 hours
Estimated price
$2 - $3
Schedules at
facebook.com
Trans Illimani
Phone
+591 2 2282025/ 76789423/ Potosí: +(591)2-6243343
Website
facebook.com
Bus from Potosí to Tupiza
Ave. Duration
4 h
Frequency
4 times a day
Estimated price
$17
Schedules at
andestransit.com
Book at
andestransit.com
El Quiaqueño
Phone
+54 (0388) 4280041 / 4281161
Email
elquiaqueosrl@yahoo.com.ar
Website
xn--elquiaqueo-19a.com
Bus from San Salvador de Jujuy to La Quiaca
Ave. Duration
4 h 25 min
Frequency
Every 3 hours
Schedules at
xn--elquiaqueo-19a.com
Panamericano de Jujuy
Phone
+54 4254336 / 4254330
Email
contable@panamericanojujuy.com.ar
Website
facebook.com
Bus from San Salvador de Jujuy to La Quiaca
Ave. Duration
6 h 20 min
Frequency
Every 4 hours
Estimated price
$7
Schedules at
facebook.com
Quechisla
Phone
+591 73858000 Atocha / 74243875 Tupiza
Website
facebook.com
Bus from Villazón to Tupiza
Ave. Duration
2 h
Frequency
3 times a day
Schedules at
facebook.com
Transporte El Inca
Phone
+591 71959249
Bus from Villazón to Tupiza
Ave. Duration
2 h
Frequency
Once daily
Schedules at
mi.lapaz.bo

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More Questions & Answers

Eco Jet, Boliviana de Aviación and LATAM Chile offer flights from La Serena Airport to Tarija Airport.

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There are 16+ hotels available in Tupiza. Prices start at $10 USD per night.

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The best way to get from La Serena to La Serena Airport is to line 883 bus which takes 16 min and costs $1.

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