There are 7 ways to get from La Serena to São Paulo by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Sao Paulo  •  9 h 29 min

  1. Fly from La Serena (LSC) to Sao Paulo (GRU) LSC - GRU

$243 - $962

Cheapest option

Bus Andesmar  •  2 days 20 h

  1. Take the bus from La Serena to San Juan
  2. Take the bus from San Juan to Puerto Iguazu
  3. Take the bus from Foz do Iguaçu to São Paulo - Barra Funda

$111 - $234

5 alternative options

Fly to Sao Paulo Congonhas  •  11 h 51 min

  1. Fly from La Serena (LSC) to Sao Paulo Congonhas (CGH) LSC - CGH

$312 - $1,202

Bus JBL Turismo  •  2 days 5 h

  1. Take the bus from La Serena to Santiago
  2. Take the bus from Santiago to Rio de Janeiro
  3. Take the bus from Rio de Janeiro - Novo Rio to São Paulo - Tietê

$158 - $255

Bus via Montevideo  •  2 days 16 h

  1. Take the bus from La Serena to Mendoza
  2. Take the bus from Mendoza to Montevideo
  3. Take the bus from Montevideo to São Paulo

$274 - $466

Bus Pullman Del Sur  •  2 days 17 h

  1. Take the bus from Coquimbo to Santiago
  2. Take the bus from Santiago - Sur to Asunción
  3. Take the bus from Asunción to Sao Paulo

$193 - $291

Drive  •  44 h 41 min

  1. Drive from La Serena to São Paulo 2334 miles

$390 - $600

Questions & Answers

The cheapest way to get from La Serena to São Paulo is to bus which costs $110 - $240 and takes 2 days 20 h.

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The quickest way to get from La Serena to São Paulo is to fly which costs $240 - $1,000 and takes 9 h 29 min.

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No, there is no direct bus from La Serena to São Paulo. However, there are services departing from La Serena and arriving at R. Líbero Badaró, 170 via Mendoza, Montevideo and Terminal Barra Funda Lado Sul Plat. C. The journey, including transfers, takes approximately 2 days 16 h.

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The distance between La Serena and São Paulo is 2539 km. The road distance is 3734.3 km.

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The best way to get from La Serena to São Paulo without a car is to bus which takes 2 days 5 h and costs $150 - $260.

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It takes approximately 9 h 29 min to get from La Serena to São Paulo, including transfers.

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La Serena to São Paulo bus services, operated by Covalle Bus, depart from La Serena station.

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The best way to get from La Serena to São Paulo is to fly which takes 9 h 29 min and costs $240 - $1,000. Alternatively, you can bus, which costs $150 - $260 and takes 2 days 5 h.

Mode details

There is no direct flight from La Serena Airport to Sao Paulo Airport. The quickest flight takes 5 h 41 min and has one stopover.

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La Serena to São Paulo bus services, operated by EGA, arrive at São Paulo station.

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Map of how to get from La Serena to São Paulo.
Launch map view
  • Distance: 1586.7 miles
  • Duration: 9 h 29 min

What companies run services between La Serena, Chile and São Paulo, Brazil?

LATAM Chile, Sky Airline and two other airlines fly from La Serena to São Paulo every 3 hours. Alternatively, you can take a bus from La Serena to São Paulo via Santiago, PI341 - Parada 1 /, PI1179 - Parada / Terminal San Borja, Santiago, Rio de Janeiro, Rio de Janeiro - Novo Rio, São Paulo - Tietê, and Portuguesa Tietê in around 2 days 5 h.

Airlines
LATAM Chile
Website
latam.com
Flights from La Serena to Sao Paulo via Santiago
Ave. Duration
7 h 1 min
When
Monday and Tuesday
Estimated price
$240 - $950
Flights from La Serena to Sao Paulo via Santiago, Rosario
Ave. Duration
8 h 13 min
When
Sunday
Estimated price
$240 - $950
Flights from La Serena to Sao Paulo via Santiago, Asuncion
Ave. Duration
8 h 13 min
When
Monday
Estimated price
$240 - $950
Flights from La Serena to Sao Paulo via Santiago, Rio De Janeiro-Galeao
Ave. Duration
8 h 30 min
When
Tuesday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$260 - $1,000
Flights from La Serena to Sao Paulo via Santiago, Tucuman
Ave. Duration
8 h 40 min
When
Wednesday, Thursday and Saturday
Estimated price
$250 - $950
Flights from La Serena to Sao Paulo via Santiago, Buenos Aires Ministro Pistarini
Ave. Duration
9 h 4 min
When
Monday and Tuesday
Estimated price
$250 - $950
Flights from La Serena to Sao Paulo via Antofagasta, Santiago
Ave. Duration
10 h 12 min
When
Friday
Estimated price
$300 - $1,100
Flights from La Serena to Sao Paulo Congonhas via Santiago, Rio De Janeiro-Galeao
Ave. Duration
9 h 46 min
When
Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$310 - $1,200
Flights from La Serena to Sao Paulo Congonhas via Calama, Santiago, Rio De Janeiro-Galeao
Ave. Duration
13 h 41 min
When
Friday
Estimated price
$390 - $1,300
Flights from La Serena to Sao Paulo Congonhas via Santiago, Sao Paulo, Florianopolis
Ave. Duration
14 h 30 min
When
Thursday
Estimated price
$320 - $1,200
Flights from La Serena to Sao Paulo Congonhas via Santiago, Sao Paulo, Rio De Janeiro Santos Dumont
Ave. Duration
15 h
When
Monday
Estimated price
$310 - $1,200
Flights from La Serena to Sao Paulo Congonhas via Santiago, Sao Paulo, Curitiba
Ave. Duration
15 h 30 min
When
Monday
Estimated price
$310 - $1,200
Flights from La Serena to Sao Paulo Congonhas via Santiago, Sao Paulo, Sao Jose Do Rio Preto
Ave. Duration
15 h 58 min
When
Friday
Estimated price
$310 - $1,200
Bus operators
Turbus
Phone
+56 22 822 7500
Email
atencion_clientes@turbus.cl
Website
turbus.cl
Bus from La Serena to Santiago
Ave. Duration
5 h 50 min
Frequency
Hourly
Estimated price
$11 - $40
Schedules at
turbus.cl
2nd Class
$11 - $23
Premium
$26 - $40
1st Class
$26 - $40
Bus from Coquimbo to Santiago
Ave. Duration
5 h 25 min
Frequency
Every 2 hours
Estimated price
$10 - $40
Schedules at
turbus.cl
2nd Class
$10 - $22
Premium
$26 - $40
1st Class
$26 - $40
JBL Turismo
Phone
+55 51 3475.4440 / 0800 6484440
Email
contato@jblturismo.com.br
Website
jblturismo.com.br
Bus from Santiago to Rio de Janeiro
Ave. Duration
40 h
Frequency
Once a week
Estimated price
$120 - $180
Schedules at
jblturismo.com.br
Book at
jblturismo.com.br
CONVENCIONAL
$120 - $160
LEITO
$150 - $180
Kaissara
Phone
0800 723 2121 / 0800 726 0246
Email
faleconosco@kaissara.com.br
Website
kaissara.com.br
Bus from Rio de Janeiro - Novo Rio to São Paulo - Tietê
Ave. Duration
6 h
Frequency
Every 4 hours
Estimated price
$24 - $35
Book at
ad.zanox.com
Executive
$24 - $35
Conventional
$24 - $35
Business
$30 - $45
First Class
$40 - $55
Covalle Bus
Phone
+56 51 221 3127
Bus from La Serena to Mendoza
Ave. Duration
12 h
Frequency
Once daily
Cata International
Phone
0800-122-2282
Email
atencionalcliente@catainternacional.com
Website
catainternacional.com
Bus from La Serena to Mendoza
Ave. Duration
13 h 25 min
Frequency
5 times a week
Estimated price
$2 - $40
Schedules at
catainternacional.com
Promo Semi Cama
$14 - $19
Semi Cama
$20 - $25
Cama
$25 - $29
Suite
$25 - $40
Bus from La Serena to San Juan
Ave. Duration
15 h 35 min
Frequency
5 times a week
Estimated price
$2 - $45
Schedules at
catainternacional.com
Promo Semi Cama
$17 - $23
Semi Cama
$24 - $35
Cama
$31 - $35
Suite
$30 - $45
EGA
Website
ega.com.uy
Bus from Mendoza to Montevideo
Ave. Duration
20 h 45 min
Frequency
Once a week
Estimated price
$120 - $190
Schedules at
ega.com.uy
Book at
ecommerce.sittnet.net
Bed
$130 - $190
Regular
$120 - $150
Bus from Montevideo to São Paulo
Ave. Duration
29 h
Frequency
Once a week
Estimated price
$150 - $240
Schedules at
ega.com.uy
Book at
ecommerce.sittnet.net
Bed
$170 - $240
Regular
$150 - $200
Pullman Del Sur
Website
pdelsur.cl
Bus from Santiago - Sur to Asunción
Ave. Duration
36 h
Frequency
Once a week
Estimated price
$143
Schedules at
pdelsur.cl
Book at
pdelsur.cl
Crucero Del Norte
Website
crucerodelnorte.com.ar
Bus from Asunción to Sao Paulo
Ave. Duration
20 h 25 min
Frequency
Twice daily
Estimated price
$30 - $55
Schedules at
crucerodelnorte.com.ar
Book at
crucerodelnorte.com.ar
Semi Cama
$30 - $45
Suite
$45 - $60
Cama
$40 - $55
NSA
Phone
+595 21 289 1000
Email
info@nsa.com.py
Website
nsa.com.py
Bus from Asunción to São Paulo – Tietê
Ave. Duration
21 h
Frequency
Once daily
Estimated price
$40 - $95
Schedules at
nsa.com.py
Andesmar
Phone
1 786 233 7639
Email
gestionesatc@andesmar.com.ar
Website
andesmar.com
Bus from San Juan to Puerto Iguazu
Ave. Duration
33 h 55 min
Frequency
Once daily
Estimated price
$45 - $110
Schedules at
andesmar.com
Book at
andesmar.com
Economy
$45 - $65
Executive
$70 - $100
Suite
$90 - $110
Semi Cama
$75
Cama
$104

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More Questions & Answers

São Paulo is 1 h ahead of La Serena. It is currently 4:36 AM in La Serena and 4:36 AM in São Paulo.

Yes, the driving distance between La Serena to São Paulo is 3734 km. It takes approximately 44 h 41 min to drive from La Serena to São Paulo.

Get driving directions

LATAM Chile offers flights from La Serena Airport to Sao Paulo Airport.

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There are 1481+ hotels available in São Paulo. Prices start at $19 USD per night.

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The best way to get from La Serena to La Serena Airport is to line 883 bus which takes 16 min and costs $1.

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