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There are 6 ways to get from La Serena to São Paulo by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Sao Paulo Congonhas  •  11 h 50 min

  1. Fly from La Serena (LSC) to Sao Paulo Congonhas (CGH) LSC - CGH

$283 - $1,103

Cheapest option

Bus Andesmar  •  2 days 21 h

  1. Take the bus from La Serena to San Juan
  2. Take the bus from San Juan to Puerto Iguazu
  3. Take the bus from Foz do Iguaçu to São Paulo - Barra Funda

$108 - $302

4 alternative options

Fly to Sao Paulo  •  9 h 42 min

  1. Fly from La Serena (LSC) to Sao Paulo (GRU) LSC - GRU

$245 - $964

Bus JBL Turismo  •  2 days 5 h

  1. Take the bus from La Serena to Santiago
  2. Take the bus from Santiago to Rio de Janeiro
  3. Take the bus from Rio de Janeiro - Novo Rio to São Paulo - Tietê

$162 - $264

Bus Pullman Del Sur  •  2 days 18 h

  1. Take the bus from La Serena to Santiago
  2. Take the bus from Santiago - Sur to Asunción
  3. Take the bus from Asunción to São Paulo – Princesa Isabel

$191 - $247

Drive  •  44 h 41 min

  1. Drive from La Serena to São Paulo 2334 miles

$390 - $600

Questions & Answers

The cheapest way to get from La Serena to São Paulo is to bus which costs $160 - $270 and takes 2 days 5 h.

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The quickest way to get from La Serena to São Paulo is to fly which costs $240 - $1,000 and takes 9 h 42 min.

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No, there is no direct bus from La Serena to São Paulo. However, there are services departing from La Serena and arriving at São Paulo - Tietê via PI341 - Parada 1 /, Santiago and Rio de Janeiro - Novo Rio. The journey, including transfers, takes approximately 2 days 5 h.

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The distance between La Serena and São Paulo is 2539 km. The road distance is 3734.3 km.

Get driving directions

The best way to get from La Serena to São Paulo without a car is to bus which takes 2 days 5 h and costs $160 - $270.

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It takes approximately 11 h 50 min to get from La Serena to São Paulo, including transfers.

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La Serena to São Paulo bus services, operated by Turbus, depart from La Serena station.

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The best way to get from La Serena to São Paulo is to fly which takes 11 h 50 min and costs $280 - $1,100. Alternatively, you can bus, which costs $160 - $270 and takes 2 days 5 h.

Mode details

There is no direct flight from La Serena Airport to Sao Paulo Congonhas Airport. The quickest flight takes 9 h 1 min and has two stopovers.

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La Serena to São Paulo bus services, operated by Expresso Do Sul, arrive at São Paulo - Tietê station.

More details

Map of how to get from La Serena to São Paulo.
Launch map view
  • Distance: 1586.7 miles
  • Duration: 11 h 50 min

What companies run services between La Serena, Chile and São Paulo, Brazil?

LATAM Chile, JetSMART and Gol Transportes Aéreos fly from La Serena to São Paulo 4 times a day. Alternatively, you can take a bus from La Serena to São Paulo via Santiago, PI341 - Parada 1 /, PI1179 - Parada / Terminal San Borja, Santiago, and Rio de Janeiro - Novo Rio in around 2 days 5 h.

Airlines
LATAM Chile
Website
latam.com
Flights from La Serena to Sao Paulo Congonhas via Santiago, Rio De Janeiro-Galeao
Ave. Duration
9 h 21 min
When
Monday, Tuesday, Thursday, Friday and Sunday
Estimated price
$310 - $1,200
Flights from La Serena to Sao Paulo Congonhas via Santiago, Florianopolis
Ave. Duration
16 h 48 min
When
Tuesday
Estimated price
$280 - $1,100
Flights from La Serena to Sao Paulo Congonhas via Santiago, Porto Alegre
Ave. Duration
17 h 43 min
When
Tuesday
Estimated price
$280 - $1,100
Flights from La Serena to Sao Paulo via Santiago
Ave. Duration
6 h 21 min
When
Every day
Estimated price
$240 - $950
Flights from La Serena to Sao Paulo via Santiago, Tucuman
Ave. Duration
7 h 44 min
When
Wednesday
Estimated price
$250 - $950
Flights from La Serena to Sao Paulo via Santiago, Asuncion
Ave. Duration
7 h 59 min
When
Monday, Tuesday, Wednesday, Friday and Sunday
Estimated price
$240 - $950
Flights from La Serena to Sao Paulo via Santiago, Mendoza
Ave. Duration
8 h 1 min
When
Tuesday
Estimated price
$240 - $950
Flights from La Serena to Sao Paulo via Santiago, Rosario
Ave. Duration
8 h 19 min
When
Monday, Tuesday and Sunday
Estimated price
$240 - $950
Flights from La Serena to Sao Paulo via Santiago, Rio De Janeiro-Galeao
Ave. Duration
9 h 23 min
When
Monday, Tuesday, Thursday, Friday and Saturday
Estimated price
$260 - $1,000
Flights from La Serena to Sao Paulo via Santiago, Porto Alegre
Ave. Duration
8 h 58 min
When
Tuesday
Estimated price
$240 - $950
Flights from La Serena to Sao Paulo via Antofagasta, Santiago
Ave. Duration
9 h 44 min
When
Thursday
Estimated price
$300 - $1,100
Bus operators
Turbus
Phone
+56 22 822 7500
Email
atencion_clientes@turbus.cl
Website
turbus.cl
Bus from La Serena to Santiago
Ave. Duration
6 h 5 min
Frequency
Hourly
Estimated price
$10 - $22
Schedules at
turbus.cl
Premium
$26 - $40
1st Class
$26 - $40
2nd Class
$10 - $22
JBL Turismo
Phone
+55 51 3475.4440 / 0800 6484440
Email
contato@jblturismo.com.br
Website
jblturismo.com.br
Bus from Santiago to Rio de Janeiro
Ave. Duration
40 h
Frequency
Once a week
Estimated price
$130 - $200
Schedules at
jblturismo.com.br
Book at
jblturismo.com.br
CONVENCIONAL
$130 - $170
LEITO
$160 - $200
Kaissara
Phone
0800 723 2121 / 0800 726 0246
Email
faleconosco@kaissara.com.br
Website
kaissara.com.br
Bus from Rio de Janeiro - Novo Rio to São Paulo - Tietê
Ave. Duration
6 h
Frequency
Every 4 hours
Estimated price
$27 - $35
Book at
ad.zanox.com
Executive
$26 - $40
Conventional
$27 - $35
Business
$30 - $45
First Class
$45 - $60
Pullman Del Sur
Phone
+56 2 776-2426
Website
pdelsur.cl
Bus from Santiago - Sur to Asunción
Ave. Duration
36 h
Frequency
Once a week
Estimated price
$140
Schedules at
pdelsur.cl
Book at
pdelsur.cl
NSA
Phone
+595 21 289 1000
Email
info@nsa.com.py
Website
nsa.com.py
Bus from Asunción to São Paulo – Princesa Isabel
Ave. Duration
22 h
Frequency
Once daily
Estimated price
$40 - $85
Schedules at
nsa.com.py
Convencional
$60 - $85
Andesmar
Phone
1 786 233 7639
Email
gestionesatc@andesmar.com.ar
Website
andesmar.com
Bus from San Juan to Puerto Iguazu
Ave. Duration
33 h 55 min
Frequency
Once daily
Estimated price
$45 - $110
Schedules at
andesmar.com
Book at
andesmar.com
Economy
$45 - $70
Executive
$70 - $100
Suite
$95 - $110
Semi Cama
$76
Cama
$106
Auto Viação Catarinense
Phone
0800-470-470 / +55 4002-4700
Email
sac@catarinense.com.br
Website
catarinense.com.br
Bus from Foz do Iguaçu to São Paulo - Barra Funda
Ave. Duration
17 h 45 min
Frequency
4 times a day
Estimated price
$50 - $120
Book at
vendas.jcaholding.com.br
Convencional
$50 - $75
Semi Leito
$55 - $75
Leito
$85 - $120

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including Getting to Rome from the airport, Train travel in Spain: A guide to Renfe and How to get from Heathrow Airport into central London - to help you get the most out of your next trip.

More Questions & Answers

São Paulo is 1 h ahead of La Serena. It is currently 3:48 PM in La Serena and 4:48 PM in São Paulo.

Yes, the driving distance between La Serena to São Paulo is 3734 km. It takes approximately 44 h 41 min to drive from La Serena to São Paulo.

Get driving directions

JetSMART and LATAM Chile offer flights from La Serena Airport to Sao Paulo Congonhas Airport.

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There are 1585+ hotels available in São Paulo. Prices start at $22 USD per night.

More details

The best way to get from La Serena to La Serena Airport is to line 8113 bus which takes 24 min and costs $1.

More details