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There are 5 ways to get from La Serena to Cusco by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  8 h 9 min

  1. Fly from La Serena (LSC) to Cuzco (CUZ) LSC - CUZ

$283 - $1,105

Cheapest option

Bus  •  37 h 14 min

  1. Take the bus from La Serena to Arica
  2. Take the bus from Arica to Tacna
  3. Take the bus from Tacna to Arequipa
  4. Take the bus from Arequipa to Cusco

$54 - $203

3 alternative options

Bus via Iquique  •  40 h

  1. Take the bus from La Serena to Iquique
  2. Take the bus from Iquique to Arica
  3. Take the bus from Arica to Tacna
  4. Take the bus from Tacna to Arequipa
  5. Take the bus from Arequipa to Cusco

$70 - $194

Bus, train  •  2 days 21 h

  1. Take the bus from La Serena to Arica
  2. Take the bus from Arica to Tacna
  3. Take the bus from Tacna to Arequipa
  4. Take the train from Arequipa to Cusco - Wanchaq

$255 - $6,153

Drive  •  32 h 1 min

  1. Drive from La Serena to Cusco 1511.7 miles

$250 - $370

Questions & Answers

The cheapest way to get from La Serena to Cusco is to bus which costs $50 - $210 and takes 37 h 14 min.

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The quickest way to get from La Serena to Cusco is to fly which costs $280 - $1,100 and takes 8 h 9 min.

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No, there is no direct bus from La Serena to Cusco. However, there are services departing from La Serena and arriving at Cusco via Arica, Tacna and Arequipa. The journey, including transfers, takes approximately 37 h 14 min.

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The distance between La Serena and Cusco is 1823 km. The road distance is 2418.7 km.

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The best way to get from La Serena to Cusco without a car is to bus which takes 37 h 14 min and costs $50 - $210.

More details

It takes approximately 8 h 9 min to get from La Serena to Cusco, including transfers.

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La Serena to Cusco bus services, operated by Pullman Bus, depart from La Serena station.

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The best way to get from La Serena to Cusco is to fly which takes 8 h 9 min and costs $280 - $1,100. Alternatively, you can bus, which costs $50 - $210 and takes 37 h 14 min.

Mode details

There is no direct flight from La Serena Airport to Cuzco Airport. The quickest flight takes 5 h 35 min and has one stopover.

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La Serena to Cusco bus services, operated by Transportes Reyna, arrive at Cusco station.

More details

Map of how to get from La Serena to Cusco.
Launch map view
  • Distance: 1139.4 miles
  • Duration: 8 h 9 min

What companies run services between La Serena, Chile and Cusco, Peru?

LATAM Chile, JetSMART and Sky Airline fly from La Serena to Cusco 5 times a day. Alternatively, you can take a bus from La Serena to Cusco via Arica, Tacna, and Arequipa in around 37 h 14 min.

Airlines
LATAM Chile
Website
latam.com
Flights from La Serena to Cuzco via Santiago
Ave. Duration
6 h 10 min
When
Friday
Estimated price
$280 - $1,100
Flights from La Serena to Cuzco via Santiago, Lima
Ave. Duration
9 h 14 min
When
Tuesday and Friday
Estimated price
$320 - $1,200
Train operators
PeruRail
Phone
51-84-581414
Email
reservas@perurail.com
Website
perurail.com
Train from Arequipa to Cusco - Wanchaq
Ave. Duration
40 h 58 min
Frequency
Once a week
Estimated price
$210 - $6,000
Schedules at
perurail.com
Book at
pax1.perurail.com
VIP
$210 - $6,000
Regular
$600 - $850
Bus operators
Pullman Bus
Phone
600 320 3200
Website
pullman.cl
Bus from La Serena to Arica
Ave. Duration
19 h 50 min
Frequency
4 times a day
Estimated price
$50 - $70
Schedules at
pullman.cl
Bus from La Serena to Iquique
Ave. Duration
17 h 30 min
Frequency
5 times a day
Estimated price
$40 - $60
Schedules at
pullman.cl
Turbus
Phone
+56 22 822 7500
Email
atencion_clientes@turbus.cl
Website
turbus.cl
Bus from La Serena to Arica
Ave. Duration
21 h 35 min
Frequency
4 times a day
Estimated price
$30 - $100
Schedules at
turbus.cl
2nd Class
$30 - $70
Premium
$70 - $100
1st Class
$90 - $130
Bus from Iquique to Arica
Ave. Duration
4 h 35 min
Frequency
3 times a day
Estimated price
$7 - $28
Schedules at
turbus.cl
2nd Class
$7 - $17
Premium
$20 - $28
1st Class
$17 - $25
Pullman Carmelita
Phone
+56 (57) 248 3147
Bus from La Serena to Arica
Ave. Duration
24 h 27 min
Frequency
Once daily
Estimated price
$50 - $65
Schedules at
voyhoy.com
Adsubliata
Phone
+56 58 262 495
Website
terminaldebuses.com
Bus from Arica to Tacna
Ave. Duration
1 h
Frequency
Hourly
Estimated price
$6
Schedules at
terminaldebuses.com
Chasquitur
Phone
+56 58 231967
Website
terminaldebuses.com
Bus from Arica to Tacna
Ave. Duration
1 h
Frequency
Hourly
Estimated price
$3
Schedules at
bus-america.com
Buses Norte Grande
Phone
+56 58 222 8603
Email
busesnortegrande_zarzuri@hotmail.com
Website
busesng.cl
Bus from Arica to Tacna
Ave. Duration
1 h
Frequency
Hourly
Estimated price
$3
Schedules at
busesng.cl
Book at
busesng.cl
Flores Hermanos
Phone
+51 1 4800725
Email
floresruta@floreshnos.com
Website
floreshnos.pe
Bus from Tacna to Arequipa
Ave. Duration
6 h
Frequency
Hourly
Estimated price
$9 - $24
Schedules at
floreshnos.pe
Bus from Arequipa to Cusco
Ave. Duration
11 h
Frequency
Twice daily
Estimated price
$13 - $24
Schedules at
floreshnos.pe
Skybus
Phone
+58 414 8448807
Website
facebook.com
Bus from Tacna to Arequipa
Ave. Duration
4 h
Frequency
Once daily
Schedules at
facebook.com
Oltursa
Phone
+511 708 5000
Website
oltursa.pe
Bus from Tacna to Arequipa
Ave. Duration
5 h 30 min
Frequency
Once daily
Estimated price
$10 - $50
Schedules at
oltursa.pe
Book at
oltursa.pe
Double VIP
$30 - $50
Bed
$14 - $19
VIP
$21 - $30
Bus from Arequipa to Cusco
Ave. Duration
10 h 15 min
Frequency
Twice daily
Estimated price
$14 - $50
Schedules at
oltursa.pe
Double VIP
$35 - $50
Bed
$16 - $22
VIP
$24 - $35
Movil Tours
Phone
+51 1 716-8000
Email
info@moviltours.com.pe
Website
moviltours.com.pe
Bus from Arequipa to Cusco
Ave. Duration
10 h
Frequency
Once daily
Estimated price
$17 - $45
Schedules at
moviltours.com.pe
Economy
$17 - $25
Regular
$22 - $35
Suite
$30 - $45
Transzela
Peru Hop
Phone
+51 1 2422140
Email
info@peruhop.com
Bus from Arequipa to Cusco
Ave. Duration
23 h 45 min
Frequency
4 times a day
Estimated price
$85 - $180
Schedules at
peruhop.com
Book at
peruhop.com
Ciktur
Phone
951690977
Email
servicioalcliente@ciktur.cl
Website
ciktur.cl
Bus from La Serena to Iquique
Ave. Duration
18 h 22 min
Frequency
3 times a day
Estimated price
$60
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Buses Evans
Website
busesevans.com
Bus from La Serena to Iquique
Ave. Duration
14 h 37 min
Frequency
Once daily
Schedules at
busesevans.com

Want to know more about travelling around the world?

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More Questions & Answers

Cusco is 1 h behind La Serena. It is currently 2:27 PM in La Serena and 12:27 PM in Cusco.

Yes, the driving distance between La Serena to Cusco is 2419 km. It takes approximately 32 h 1 min to drive from La Serena to Cusco.

Get driving directions

JetSMART and LATAM Chile offer flights from La Serena Airport to Cuzco Airport.

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There are 1381+ hotels available in Cusco. Prices start at $18 USD per night.

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The best way to get from La Serena to La Serena Airport is to line 8113 bus which takes 24 min and costs $1.

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