There are 4 ways to get from La Serena to Cusco by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  9 h 3 min

  1. Fly from La Serena (LSC) to Cuzco (CUZ) LSC - CUZ

$286 - $1,098

Cheapest option

Bus  •  38 h 48 min

  1. Take the bus from La Serena to Arica
  2. Take the bus from Arica to Tacna
  3. Take the bus from Tacna to Arequipa
  4. Take the bus from Arequipa to Cusco

$61 - $187

2 alternative options

Bus, Tour  •  43 h 55 min

  1. Take the bus from La Serena to Iquique
  2. Take the bus from Iquique to Arica
  3. Take the bus from Arica to Tacna
  4. Take the bus from Tacna to Arequipa
  5. Take the Tour from Arequipa to Cusco

$125 - $224

Drive  •  32 h 1 min

  1. Drive from La Serena to Cusco 1511.7 miles

$250 - $370

Questions & Answers

The cheapest way to get from La Serena to Cusco is to bus which costs $60 - $190 and takes 38 h 48 min.

More details

The quickest way to get from La Serena to Cusco is to fly which costs $280 - $1,100 and takes 9 h 3 min.

More details

The distance between La Serena and Cusco is 1823 km. The road distance is 2418.7 km.

Get driving directions

It takes approximately 9 h 3 min to get from La Serena to Cusco, including transfers.

More details

No, there is no direct bus from La Serena to Cusco. However, there are services departing from La Serena and arriving at Cusco via Arica, Tacna and Arequipa. The journey, including transfers, takes approximately 38 h 48 min.

More details

The best way to get from La Serena to Cusco without a car is to bus which takes 38 h 48 min and costs $60 - $190.

More details

La Serena to Cusco bus services, operated by Expreso Norte, arrive at Arica station.

More details

Map of how to get from La Serena to Cusco.
Launch map view
  • Distance: 1139.4 miles
  • Duration: 9 h 3 min

What companies run services between La Serena, Chile and Cusco, Peru?

LATAM Chile and Sky Airline fly from La Serena to Cusco 5 times a day. Alternatively, you can take a bus from La Serena to Cusco via Arica, Tacna, and Arequipa in around 38 h 48 min.

Airlines
LATAM Chile
Website
latam.com
Flights from La Serena to Cuzco via Santiago
Ave. Duration
7 h 28 min
When
Tuesday, Wednesday and Saturday
Estimated price
$280 - $1,100
Flights from La Serena to Cuzco via Santiago, Lima
Ave. Duration
9 h 45 min
When
Monday, Friday and Sunday
Estimated price
$320 - $1,200
Bus operators
Pullman Bus
Phone
600 320 3200
Website
pullman.cl
Bus from La Serena to Arica
Ave. Duration
21 h 25 min
Frequency
Twice daily
Estimated price
$40 - $70
Schedules at
pullman.cl
Bus from La Serena to Iquique
Ave. Duration
18 h 13 min
Frequency
Twice daily
Estimated price
$30 - $55
Schedules at
pullman.cl
Bus from Iquique to Arica
Ave. Duration
3 h 12 min
Frequency
Twice daily
Estimated price
$11 - $15
Schedules at
pullman.cl
Turbus
Website
turbus.cl
Bus from La Serena to Arica
Ave. Duration
21 h 35 min
Frequency
Once daily
Estimated price
$35 - $100
Schedules at
turbus.cl
2nd Class
$35 - $70
Premium
$70 - $100
1st Class
$90 - $130
Adsubliata
Phone
+56 58 58 226 2495
Bus from Arica to Tacna
Ave. Duration
1 h
Frequency
Every 30 minutes
Estimated price
$3
Buses Norte Grande
Phone
+56993068508
Website
busesnortegrande.cl
Bus from Arica to Tacna
Ave. Duration
1 h
Frequency
Hourly
Estimated price
$3
Schedules at
busesnortegrande.cl
Oltursa
Website
oltursa.pe
Bus from Tacna to Arequipa
Ave. Duration
5 h 30 min
Frequency
Once daily
Estimated price
$10 - $25
Schedules at
oltursa.pe
Book at
oltursa.pe
Bus from Arequipa to Cusco
Ave. Duration
10 h 15 min
Frequency
Twice daily
Estimated price
$14 - $35
Schedules at
oltursa.pe
Movil Tours
Phone
716-8000
Email
info@moviltours.com.pe
Website
moviltours.com.pe
Bus from Arequipa to Cusco
Ave. Duration
10 h
Frequency
Once daily
Estimated price
$18 - $60
Schedules at
moviltours.com.pe
Economy
$21 - $35
Regular
$27 - $40
Suite
$40 - $60
Transzela
Ciktur
Phone
951690977
Email
servicioalcliente@ciktur.cl
Website
ciktur.cl
Bus from La Serena to Iquique
Ave. Duration
18 h 22 min
Frequency
3 times a day
Estimated price
$61
Schedules at
ciktur.cl
Book at
altanetpasajes.cl
Buses Evans
Website
busesevans.com
Bus from La Serena to Iquique
Ave. Duration
14 h 37 min
Frequency
Once daily
Schedules at
busesevans.com
Frontera del Norte
Phone
+56 065-280 999 / 9 6633 7480
Website
facebook.com
Bus from Iquique to Arica
Ave. Duration
3 h 59 min
Frequency
Once daily
Schedules at
recorrido.cl
Atacama VIP
Phone
600 600 7855 / 600 660 0111
Website
avip.cl
Bus from Iquique to Arica
Ave. Duration
4 h 15 min
Frequency
Once daily
Schedules at
recorrido.cl
Peru Hop
Phone
+51 1 2422140
Email
info@peruhop.com
Bus from Arequipa to Cusco
Ave. Duration
11 h 45 min
Frequency
Once daily
Estimated price
$70 - $120
Schedules at
peruhop.com
Book at
peruhop.com

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