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There are 5 ways to get from La Serena to Antofagasta by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Antofagasta  •  3 h 28 min

  1. Fly from La Serena (LSC) to Antofagasta (ANF) LSC - ANF

$65 - $340

Cheapest option

Bus Turbus  •  11 h 55 min

  1. Take the bus from La Serena to Antofagasta Coquimbo / ...

$19 - $40

3 alternative options

Fly to Calama  •  3 h 37 min

  1. Fly from La Serena (LSC) to Calama (CJC) LSC - CJC

$120 - $1,010

Bus Expreso Norte  •  12 h 49 min

  1. Take the bus from La Serena to Antofagasta Valparaíso - Calama / ...

$29 - $45

Drive  •  10 h 32 min

  1. Drive from La Serena to Antofagasta 560.6 miles

$90 - $140

Questions & Answers

The cheapest way to get from La Serena to Antofagasta is to bus which costs $29 - $45 and takes 12 h 49 min.

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The quickest way to get from La Serena to Antofagasta is to fly which costs $65 - $340 and takes 3 h 28 min.

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Yes, there is a direct bus departing from La Serena and arriving at Antofagasta. Services depart hourly, and operate every day. The journey takes approximately 11 h 55 min.

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The distance between La Serena and Antofagasta is 733 km. The road distance is 897 km.

Get driving directions

The best way to get from La Serena to Antofagasta without a car is to bus which takes 11 h 55 min and costs $19 - $40.

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It takes approximately 3 h 28 min to get from La Serena to Antofagasta, including transfers.

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La Serena to Antofagasta bus services, operated by Turbus, depart from La Serena station.

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The best way to get from La Serena to Antofagasta is to fly which takes 3 h 28 min and costs $65 - $340. Alternatively, you can bus, which costs $19 - $40 and takes 11 h 55 min.

Mode details

The quickest flight from La Serena Airport to Antofagasta Airport is the direct flight which takes 1 h 15 min.

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La Serena to Antofagasta bus services, operated by Turbus, arrive at Antofagasta station.

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Map of how to get from La Serena to Antofagasta.
Launch map view
  • Distance: 458 miles
  • Duration: 3 h 28 min

What companies run services between La Serena, Chile and Antofagasta, Chile?

Sky Airline, JetSMART and LATAM Chile fly from La Serena to Antofagasta twice daily. Alternatively, Turbus operates a bus from La Serena to Antofagasta hourly. Tickets cost $19 - $40 and the journey takes 11 h 55 min.

Airlines
JetSMART
Website
jetsmart.com
Flights from La Serena to Antofagasta
Ave. Duration
1 h 17 min
When
Monday, Tuesday and Wednesday
Estimated price
$50 - $360
Flights from La Serena to Calama
Ave. Duration
1 h 40 min
When
Monday, Tuesday, Wednesday and Thursday
Estimated price
$55 - $380
Sky Airline
Website
skyairline.com
Flights from La Serena to Antofagasta
Ave. Duration
1 h 15 min
When
Every day
Estimated price
$75 - $330
LATAM Chile
Website
latam.com
Flights from La Serena to Antofagasta
Ave. Duration
1 h 18 min
When
Thursday and Friday
Estimated price
$130 - $1,100
Flights from La Serena to Calama
Ave. Duration
1 h 24 min
When
Thursday and Friday
Estimated price
$110 - $1,000
Bus operators
Turbus
Phone
+56 22 822 7500
Email
atencion_clientes@turbus.cl
Website
turbus.cl
Bus from La Serena to Antofagasta
Ave. Duration
11 h 55 min
Frequency
Hourly
Estimated price
$19 - $40
Schedules at
turbus.cl
2nd Class
$19 - $40
Premium
$40 - $60
1st Class
$45 - $70
Pluss Chile
Phone
+56 (2) 26419926
Email
info@plusschile.cl
Website
plusschile.cl
Bus from La Serena to Antofagasta
Ave. Duration
11 h 40 min
Frequency
Every 3 hours
Schedules at
plusschile.cl
Book at
altanetpasajes.cl
Pullman Bus
Phone
600 320 3200
Website
pullman.cl
Bus from La Serena to Antofagasta
Ave. Duration
12 h 20 min
Frequency
Hourly
Estimated price
$29 - $40
Schedules at
pullman.cl
Ciktur
Phone
951690977
Email
servicioalcliente@ciktur.cl
Website
ciktur.cl
Bus from La Serena to Antofagasta
Ave. Duration
11 h 55 min
Frequency
Every 3 hours
Schedules at
ciktur.cl
Book at
altanetpasajes.cl

Want to know more about travelling around the world?

Rome2rio's Travel Guide series provide vital information for the global traveller. Read our range of informative guides on popular transport routes and companies - including How to get from London City Airport into central London, Travelling Croatia’s Dalmatian Coast by boat, bus, car and train and How to get from Gatwick Airport into central London - to help you get the most out of your next trip.

More Questions & Answers

Yes, the driving distance between La Serena to Antofagasta is 897 km. It takes approximately 10 h 32 min to drive from La Serena to Antofagasta.

Get driving directions

LATAM Chile, Sky Airline and JetSMART offer flights from La Serena Airport to Antofagasta Airport.

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The best way to get from La Serena to La Serena Airport is to line 8113 bus which takes 24 min and costs $1.

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