There are 5 ways to get from La Serena to Antofagasta by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Antofagasta  •  3 h 25 min

  1. Fly from La Serena (LSC) to Antofagasta (ANF) LSC - ANF

$65 - $340

Cheapest option

Bus Turbus  •  11 h 55 min

  1. Take the bus from La Serena to Antofagasta Coquimbo / ...

$19 - $60

3 alternative options

Fly to Calama  •  3 h 32 min

  1. Fly from La Serena (LSC) to Calama (CJC) LSC - CJC

$120 - $1,010

Bus Expreso Norte  •  12 h 51 min

  1. Take the bus from La Serena to Antofagasta Valparaíso / ...

$30 - $50

Drive  •  10 h 32 min

  1. Drive from La Serena to Antofagasta 560.6 miles

$90 - $140

Questions & Answers

The cheapest way to get from La Serena to Antofagasta is to bus which costs $30 - $50 and takes 12 h 51 min.

More details

The quickest way to get from La Serena to Antofagasta is to fly which costs $65 - $340 and takes 3 h 25 min.

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Yes, there is a direct bus departing from La Serena and arriving at Antofagasta. Services depart every three hours. The journey takes approximately 11 h 55 min.

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The distance between La Serena and Antofagasta is 733 km. The road distance is 897 km.

Get driving directions

The best way to get from La Serena to Antofagasta without a car is to bus which takes 11 h 55 min and costs $19 - $60.

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It takes approximately 3 h 25 min to get from La Serena to Antofagasta, including transfers.

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La Serena to Antofagasta bus services, operated by Turbus, depart from La Serena station.

More details

The best way to get from La Serena to Antofagasta is to fly which takes 3 h 25 min and costs $65 - $340. Alternatively, you can bus, which costs $19 - $60 and takes 11 h 55 min.

Mode details

Map of how to get from La Serena to Antofagasta.
Launch map view
  • Distance: 458 miles
  • Duration: 3 h 25 min

What companies run services between La Serena, Chile and Antofagasta, Chile?

Sky Airline and LATAM Chile fly from La Serena to Antofagasta twice daily. Alternatively, Turbus operates a bus from La Serena to Antofagasta every 3 hours. Tickets cost $19 - $60 and the journey takes 11 h 55 min.

Airlines
Sky Airline
Website
skyairline.com
Flights from La Serena to Antofagasta
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$75 - $330
LATAM Chile
Website
latam.com
Flights from La Serena to Antofagasta
Ave. Duration
1 h 22 min
When
Thursday and Friday
Estimated price
$130 - $1,100
Flights from La Serena to Calama
Ave. Duration
1 h 27 min
When
Thursday and Friday
Estimated price
$110 - $1,000
Bus operators
Turbus
Phone
+56 22 822 7500
Email
atencion_clientes@turbus.cl
Website
turbus.cl
Bus from La Serena to Antofagasta
Ave. Duration
11 h 55 min
Frequency
Every 3 hours
Estimated price
$19 - $60
Schedules at
turbus.cl
2nd Class
$19 - $40
Premium
$40 - $60
1st Class
$45 - $70
Pullman Bus
Phone
600 320 3200
Website
pullman.cl
Bus from La Serena to Antofagasta
Ave. Duration
10 h 30 min
Frequency
Twice daily
Estimated price
$30 - $50
Schedules at
pullman.cl
Buses Evans
Website
busesevans.com
Bus from La Serena to Antofagasta
Ave. Duration
9 h 32 min
Frequency
Once daily
Schedules at
busesevans.com

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