There are 3 ways to get from La Mesilla to Antigua Guatemala by bus, shuttle or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus, shuttle  •  8 h 27 min

  1. Take the bus from La Mesilla to Quetzaltenango
  2. Take a shuttle bus from Quetzaltenango to Antigua Guatemala

$45 - $52

Cheapest option

Bus  •  9 h 25 min

  1. Take the bus from La Mesilla to Ciudad Guatemala La Mesilla

$18 - $43

1 alternative option

Drive  •  5 h 14 min

  1. Drive from La Mesilla to Antigua Guatemala 199.4 miles

$23 - $35

Questions & Answers

The cheapest way to get from La Mesilla to Antigua Guatemala is to drive which costs $23 - $35 and takes 5 h 14 min.

More details

The quickest way to get from La Mesilla to Antigua Guatemala is to drive which costs $23 - $35 and takes 5 h 14 min.

More details

The distance between La Mesilla and Antigua Guatemala is 180 km. The road distance is 319.1 km.

Get driving directions

It takes approximately 8 h 27 min to get from La Mesilla to Antigua Guatemala, including transfers.

More details

No, there is no direct bus from La Mesilla to Antigua Guatemala. However, there are services departing from La Mesilla and arriving at Antigua Guatemala via Plaza Barrios and Guatemala El Trebol Zona 7. The journey, including transfers, takes approximately 9 h 25 min.

More details

Map of how to get from La Mesilla to Antigua Guatemala.
Launch map view
  • Distance: 112.4 miles
  • Duration: 8 h 27 min

What companies run services between La Mesilla, Guatemala and Antigua Guatemala?

Linea Dorada operates a bus from La Mesilla to Antigua Guatemala twice daily. Tickets cost $14 - $45 and the journey takes 8 h.

Bus operators
Linea Dorada
Phone
+502 2415-8900 / 8901 / 8902 / 8911
Website
lineadorada.com.gt
Bus from La Mesilla to Quetzaltenango
Ave. Duration
4 h 57 min
Frequency
Twice daily
Estimated price
$19 - $28
Schedules at
lineadorada.com.gt
Bus from La Mesilla to Ciudad Guatemala
Ave. Duration
8 h
Frequency
Twice daily
Estimated price
$14 - $45
Schedules at
lineadorada.com.gt
Atitrans Tours & Travel
Phone
+502 78323371
Website
atitrans.net
Shuttle from Quetzaltenango to Antigua Guatemala
Ave. Duration
3 h
Frequency
On demand
Estimated price
$25
Schedules at
atitrans.net

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