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How to get fromKnoxville to Scrantonby plane, bus (Greyhound), car, bus or bus (Flixbus, Greyhound)

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There are 7 ways to get from Knoxville to Scranton by plane, bus (Greyhound), car, bus, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Wilkes-Barre/Scranton International Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Wilkes-Barre/Scranton International Airport (AVP)plane plane TYS - AVP
    4h 55m
    $207–767

  2. Drive 657.2 mi

    cheapest
    1. Drive from Knoxville to Scrantoncar car 657.2 mi
    10h 57m
    $120–174

  3. Bus

    1. Take the bus from Knoxville to New York Citybus bus Nashville
    2. Take the bus from Port Authority Bus Terminal to Scranton, PAbus bus 196 / ...
    17h 15m
    $149–248

  4. Fly to Newark Liberty International Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Newark Liberty International Airport (EWR)plane plane TYS - EWR
    2. Take the bus from Newark Penn Station to Scrantonbus bus
    5h 43m
    $357–557

  5. Fly to Laguardia Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Laguardia Airport (LGA)plane plane TYS - LGA
    2. Take the bus from Port Authority Bus Terminal to Scranton, PAbus bus
    6h 30m
    $179–715

  6. Bus via Farragut

    1. Take the bus from Knoxville to New Yorkbus bus Memphis
    2. Take the bus from Port Authority Bus Terminal to Scranton, PAbus bus 196 / ...
    17h 38m
    $212–354

  7. Bus via Allentown

    1. Take the bus from Knoxville to New York Citybus bus
    2. Take the bus from New York City Chinatown to Allentownbus bus
    3. Take the bus from Allentown to Scranton Bus Stationbus bus
    24h 34m
    $133–199

Knoxville to Scranton by bus and foot

Calendar3Weekly Services
Duration24h 34mAverage Duration
Ticket$133Cheapest Price
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Questions & Answers

What companies run services between Knoxville, TN, USA and Scranton, PA, USA?

United Airlines and American Airlines fly from Mcghee Tyson Airport (TYS) to Wilkes-Barre/Scranton International Airport (AVP) every 3 hours. Alternatively, you can take a vehicle from Knoxville to Scranton, PA via Knoxville, New York City, East Broadway, 42 St-Bryant Park, and Port Authority Bus Terminal in around 17h 15m.

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