There are 8 ways to get from Knoxville to Santa Rosa by plane, bus (Greyhound), bus, train, car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Sonoma County Airport
best- Fly from Mcghee Tyson Airport (TYS) to Sonoma County Airport (STS)plane TYS - STS
8h 35m$223–772Bus
- Take the bus from Knoxville to Jacksonbus
- Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus
- Take the bus from Indianapolis Union Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Los Angeles Union Stationbus
- Take the bus from Los Angeles Union Station to San Francisco Bus Stationbus
- Take the bus from Fremont St & Mission St to Santa Rosa Transit Mallbus
3d 1h$620–1,160Bus, train
- Take the bus from Knoxville to Jacksonbus
- Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus
- Take the train from Indianapolis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Martineztrain
- Take the bus from Martinez to Santa Rosa Amtrak Bus Stopbus
3d 4h$1,019–2,163Drive 2,511.6 mi
- Drive from Knoxville to Santa Rosacar 2,511.6 mi
40h 2m$459–663Fly to San Francisco International Airport, bus, train
- Fly from Mcghee Tyson Airport (TYS) to San Francisco International Airport (SFO)plane TYS - SFO
- Take the bus from San Francisco Airport to Larkspur - dropoffbus
- Take the train from SMART Larkspur to SMART Santa Rosa Downtowntrain
10h 9m$260–806Fly to Oakland International Airport, bus, train
- Fly from Mcghee Tyson Airport (TYS) to Oakland International Airport (OAK)plane TYS - OAK
- Take the bus from Oakland International Airport to San Rafaelbus
- Take the train from SMART San Rafael to SMART Santa Rosa Downtowntrain
10h 11m$333–1,229Fly to Norman Y. Mineta San José International Airport, BART, train
- Fly from Mcghee Tyson Airport (TYS) to Norman Y. Mineta San José International Airport (SJC)plane TYS - SJC
- Take the subway from Milpitas to El Cerrito Del Nortesubway
- Take the train from SMART San Rafael to SMART Santa Rosa Downtowntrain
11h 36m$314–1,096Bus, train via New York
- Take the bus from Knoxville, TN to New York, NYbus
- Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Martineztrain
- Take the bus from Martinez to Petalumabus
3d 17h$1,153–2,432
Mcghee Tyson Airport (TYS) to Sonoma County Airport (STS) flights
Comparing Your Travel Options
The cheapest way to get from Knoxville to Santa Rosa is to fly which costs $220 - $800 and takes 8h 35m.
The fastest way to get from Knoxville to Santa Rosa is to fly which takes 8h 35m and costs $220 - $800.
No, there is no direct bus from Knoxville to Santa Rosa. However, there are services departing from Knoxville and arriving at Santa Rosa Transit Mall via El Mezcal Grocery - Jackson, TN, Indianapolis Union Station, St Louis Bus Station, Los Angeles Union Station and Fremont St & Mission St. The journey, including transfers, takes approximately 3 days 1h.
The distance between Knoxville and Santa Rosa is 2164 miles. The road distance is 2526.3 miles.
The best way to get from Knoxville to Santa Rosa without a car is to bus which takes 3 days 1h and costs $600 - $1,200.
It takes approximately 8h 35m to get from Knoxville to Santa Rosa, including transfers.
Knoxville to Santa Rosa bus services, operated by Wanda Coach, depart from Knoxville station.
The best way to get from Knoxville to Santa Rosa is to fly which takes 8h 35m and costs $220 - $800. Alternatively, you can bus, which costs $600 - $1,200 and takes 3 days 1h.
Knoxville to Santa Rosa bus services, operated by Wanda Coach, arrive at Jackson station.
Santa Rosa is 3h behind Knoxville. It is currently 12:49 PM in Knoxville and 9:49 AM in Santa Rosa.
What companies run services between Knoxville, TN, USA and Santa Rosa, CA, USA?
American Airlines, United Airlines, and two other airlines fly from Mcghee Tyson Airport (TYS) to Sonoma County Airport (STS) twice daily. Alternatively, you can take a vehicle from Knoxville to Santa Rosa Transit Mall via Knoxville, Jackson, El Mezcal Grocery - Jackson, TN, Indianapolis, Indianapolis Union Station, St Louis Bus Station, Los Angeles Union Station, San Francisco Bus Station, and Fremont St & Mission St in around 3d 1h.
- Website
- southwest.com
Flights from Mcghee Tyson Airport to Sonoma County Airport via Denver
- Ave. Duration
- 8h 28m
- When
- Sunday and Thursday
- Estimated price
- $150–650
Flights from Mcghee Tyson Airport to San Francisco International Airport via Nashville
- Ave. Duration
- 9h 35m
- When
- Monday, Thursday, Friday, and Saturday
- Estimated price
- $170–700
Flights from Mcghee Tyson Airport to San Francisco International Airport via Denver
- Ave. Duration
- 8h 55m
- When
- Sunday, Monday, Thursday, and Friday
- Estimated price
- $170–700
Flights from Mcghee Tyson Airport to Oakland International Airport via Denver
- Ave. Duration
- 7h 19m
- When
- Every day
- Estimated price
- $250–1,100
Flights from Mcghee Tyson Airport to Oakland International Airport via Dallas
- Ave. Duration
- 8h 45m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $260–1,100
Flights from Mcghee Tyson Airport to Norman Y. Mineta San José International Airport via Denver
- Ave. Duration
- 7h 35m
- When
- Tuesday to Friday
- Estimated price
- $240–1,000
Flights from Mcghee Tyson Airport to Norman Y. Mineta San José International Airport via Dallas
- Ave. Duration
- 9h 35m
- When
- Monday, Thursday, and Friday
- Estimated price
- $250–1,100
Flights from Mcghee Tyson Airport to Norman Y. Mineta San José International Airport via Austin
- Ave. Duration
- 9h 45m
- When
- Friday
- Estimated price
- $270–1,100
Flights from Mcghee Tyson Airport to Norman Y. Mineta San José International Airport via Nashville
- Ave. Duration
- 11h 5m
- When
- Monday, Thursday, and Friday
- Estimated price
- $240–1,000
- Website
- aa.com
Flights from Mcghee Tyson Airport to Sonoma County Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 28m
- When
- Every day
- Estimated price
- $160–650
Flights from Mcghee Tyson Airport to San Francisco International Airport via Dallas/Ft.Worth
- Ave. Duration
- 7h 39m
- When
- Every day
- Estimated price
- $180–750
Flights from Mcghee Tyson Airport to Norman Y. Mineta San José International Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 14m
- When
- Every day
- Estimated price
- $250–1,100
- Website
- united.com
Flights from Mcghee Tyson Airport to San Francisco International Airport via Denver
- Ave. Duration
- 7h 14m
- When
- Every day
- Estimated price
- $170–700
Flights from Mcghee Tyson Airport to Norman Y. Mineta San José International Airport via Denver
- Ave. Duration
- 7h 7m
- When
- Every day
- Estimated price
- $240–1,000
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $60–130
- Website
- Amtrak
Train from Chicago Union Station to Martinez
- Ave. Duration
- 2d 4h
- Frequency
- Once daily
- Estimated price
- $700–1,600
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Chicago Union Station
- Ave. Duration
- 19h 32m
- Frequency
- Once daily
- Estimated price
- $300–650
- Website
- Amtrak
Train from Chicago Union Station to Martinez
- Ave. Duration
- 2d 4h
- Frequency
- Once daily
- Estimated price
- $700–1,600
- Website
- Amtrak
- Phone
- +1 707-794-3330
- Website
- sonomamarintrain.org
Train from SMART Larkspur to SMART Santa Rosa Downtown
- Ave. Duration
- 1h 6m
- Frequency
- Hourly
- Estimated price
- $1–7
- Website
- https://sonomamarintrain.org/
- Website
- https://sonomamarintrain.org/
Train from SMART San Rafael to SMART Santa Rosa Downtown
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- $1–7
- Website
- https://sonomamarintrain.org/
- Website
- https://sonomamarintrain.org/
Train from SMART San Rafael to SMART Santa Rosa Downtown
- Ave. Duration
- 59 min
- Frequency
- Hourly
- Estimated price
- $1–7
- Website
- https://sonomamarintrain.org/
- Website
- https://sonomamarintrain.org/
- Phone
- +1-510-464-6000
- Website
- BART
Subway from Milpitas to El Cerrito Del Norte
- Ave. Duration
- 1h 10m
- Frequency
- Every 30 minutes
- Estimated price
- $8–11
- Website
- BART
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- Wanda Coach
Bus from Knoxville to Jackson
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $50–75
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $50–75
Bus from Knoxville to Jackson
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $50–75
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $50–75
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- Tornado Bus Company
Bus from El Mezcal Grocery - Jackson, TN to Indianapolis
- Ave. Duration
- 7h 56m
- Frequency
- 3 times a week
- Estimated price
- $80–200
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $80–200
Bus from El Mezcal Grocery - Jackson, TN to Indianapolis
- Ave. Duration
- 7h 56m
- Frequency
- 3 times a week
- Estimated price
- $80–200
- Schedules at
- Tornado Bus Company
- Adults 11-59
- $80–200
Rome2Rio's guide to Greyhound USA
Contact DetailsContact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- Greyhound
Bus from Indianapolis Union Station to St Louis Bus Station
- Ave. Duration
- 3h 55m
- Frequency
- 3 times a day
- Estimated price
- $35–70
- Website
- Greyhound
Bus from St Louis Bus Station to Los Angeles Union Station
- Ave. Duration
- 40h 30m
- Frequency
- Once daily
- Estimated price
- $280–550
- Website
- Greyhound
Bus from Los Angeles Union Station to San Francisco Bus Station
- Ave. Duration
- 8h 5m
- Frequency
- Once daily
- Estimated price
- $55–120
- Website
- Greyhound
- Phone
- +1 415-921-5858
- bridgecomments@goldengate.org
- Website
- Golden Gate Bridge, Highway and Transportation District
Bus from Fremont St & Mission St to Santa Rosa Transit Mall
- Ave. Duration
- 1h 59m
- Frequency
- Every 4 hours
- Estimated price
- $10–14
- Website
- Golden Gate Bridge, Highway and Transportation District
- Adult
- $10–14
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Bus from Martinez to Santa Rosa Amtrak Bus Stop
- Ave. Duration
- 1h 40m
- Frequency
- 3 times a day
- Estimated price
- $19–27
- Website
- Amtrak
Bus from Martinez to Petaluma
- Ave. Duration
- 1h 10m
- Frequency
- 4 times a day
- Estimated price
- $13–19
- Website
- Amtrak
- Phone
- +1 415-461-4222
- Website
- Marin Airporter
Bus from San Francisco Airport to Larkspur - dropoff
- Ave. Duration
- 1h 6m
- Frequency
- Hourly
- Estimated price
- $32
- Website
- Marin Airporter
- Adult One-way
- $32
- Phone
- +1 707-837-8700
- Website
- Groome Transportation
Bus from Oakland International Airport to San Rafael
- Ave. Duration
- 45 min
- Frequency
- Every 3 hours
- Estimated price
- $25–55
- Website
- Groome Transportation
- First Passenger
- $25–55
- Phone
- +1 615-939-8887
- tennesseetravel@gotobus.com
- Website
- New York to Tennessee Bus
Bus from Knoxville, TN to New York, NY
- Ave. Duration
- 12h
- Frequency
- Once daily
- Estimated price
- $95–110
- Website
- New York to Tennessee Bus
- Adult One-way
- $95–110
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Booking & Getting There
Yes, the driving distance between Knoxville to Santa Rosa is 2526 miles. It takes approximately 40h 2m to drive from Knoxville to Santa Rosa.
There are 269+ hotels available in Santa Rosa.














