There are 8 ways to get from Knoxville to Santa Rosa by plane, bus (Greyhound), bus, train, car, or subway
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Sonoma County Airport
best- Fly from Mcghee Tyson Airport (TYS) to Sonoma County Airport (STS)plane TYS - STS
8h 39m$203–722Bus
- Take the bus from Knoxville to Jacksonbus
- Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus
- Take the bus from Indianapolis Union Station to St Louis Bus Stationbus
- Take the bus from St Louis Bus Station to Los Angeles Union Stationbus
- Take the bus from Los Angeles Union Station to San Francisco Bus Stationbus
- Take the bus from Fremont St & Mission St to Santa Rosa Transit Mall-Bay N1bus
3d 1h$645–960Bus, train
- Take the bus from Knoxville to Jacksonbus
- Take the bus from El Mezcal Grocery - Jackson, TN to Indianapolisbus
- Take the train from Indianapolis to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Martineztrain
- Take the bus from Martinez to Santa Rosa Amtrak Bus Stopbus
3d 4h$914–1,858Drive 2,511.6 mi
- Drive from Knoxville to Santa Rosacar 2,511.6 mi
40h 2m$459–663Fly to San Francisco International Airport, bus, train
- Fly from Mcghee Tyson Airport (TYS) to San Francisco International Airport (SFO)plane TYS - SFO
- Take the bus from San Francisco Airport to Larkspur - dropoffbus
- Take the train from SMART Larkspur to SMART Santa Rosa Downtowntrain
10h 14m$230–706Fly to Oakland International Airport, bus, train
- Fly from Mcghee Tyson Airport (TYS) to Oakland International Airport (OAK)plane TYS - OAK
- Take the bus from Oakland International Airport to San Rafaelbus
- Take the train from SMART San Rafael to SMART Santa Rosa Downtowntrain
10h 16m$283–979Fly to Norman Y. Mineta San José International Airport, BART, train
- Fly from Mcghee Tyson Airport (TYS) to Norman Y. Mineta San José International Airport (SJC)plane TYS - SJC
- Take the subway from Milpitas to El Cerrito Del Nortesubway
- Take the train from SMART San Rafael to SMART Santa Rosa Downtowntrain
11h 35m$264–946Bus, train via New York
- Take the bus from Knoxville, TN to New York, NYbus
- Take the train from Ny Moynihan Train Hall At Penn Station to Chicago Union Stationtrain
- Take the train from Chicago Union Station to Martineztrain
- Take the bus from Martinez to Petalumabus
3d 17h$989–2,128
Mcghee Tyson Airport (TYS) to Sonoma County Airport (STS) flights
Comparing Your Travel Options
The cheapest way to get from Knoxville to Santa Rosa is to fly which costs $200 - $750 and takes 8h 39m.
The fastest way to get from Knoxville to Santa Rosa is to fly which takes 8h 39m and costs $200 - $750.
No, there is no direct bus from Knoxville to Santa Rosa. However, there are services departing from Knoxville and arriving at Santa Rosa Transit Mall-Bay N1 via El Mezcal Grocery - Jackson, TN, Indianapolis Union Station, St Louis Bus Station, Los Angeles Union Station and Fremont St & Mission St. The journey, including transfers, takes approximately 3 days 1h.
The distance between Knoxville and Santa Rosa is 2164 miles. The road distance is 2526.3 miles.
The best way to get from Knoxville to Santa Rosa without a car is to bus which takes 3 days 1h and costs $600 - $1,000.
It takes approximately 8h 39m to get from Knoxville to Santa Rosa, including transfers.
Knoxville to Santa Rosa bus services, operated by Wanda Coach, depart from Knoxville station.
The best way to get from Knoxville to Santa Rosa is to fly which takes 8h 39m and costs $200 - $750. Alternatively, you can bus, which costs $600 - $1,000 and takes 3 days 1h.
Knoxville to Santa Rosa bus services, operated by Wanda Coach, arrive at Jackson station.
Santa Rosa is 3h behind Knoxville. It is currently 7:04 PM in Knoxville and 4:04 PM in Santa Rosa.
What companies run services between Knoxville, TN, USA and Santa Rosa, CA, USA?
American Airlines, Allegiant Air, and Southwest Airlines fly from Mcghee Tyson Airport (TYS) to Sonoma County Airport (STS) once daily. Alternatively, you can take a vehicle from Knoxville to Santa Rosa Transit Mall-Bay N1 via Knoxville, Jackson, El Mezcal Grocery - Jackson, TN, Indianapolis, Indianapolis Union Station, St Louis Bus Station, Los Angeles Union Station, San Francisco Bus Station, and Fremont St & Mission St in around 3d 1h.
- Website
- southwest.com
Flights from Mcghee Tyson Airport to Sonoma County Airport via Denver
- Ave. Duration
- 9h 5m
- When
- Sunday
- Estimated price
- $130–600
Flights from Mcghee Tyson Airport to San Francisco International Airport via Denver
- Ave. Duration
- 7h 47m
- When
- Saturday and Sunday
- Estimated price
- $140–600
Flights from Mcghee Tyson Airport to San Francisco International Airport via Nashville
- Ave. Duration
- 9h 27m
- When
- Monday to Wednesday
- Estimated price
- $140–600
Flights from Mcghee Tyson Airport to Oakland International Airport via Denver
- Ave. Duration
- 7h 19m
- When
- Every day
- Estimated price
- $200–850
Flights from Mcghee Tyson Airport to Oakland International Airport via Phoenix
- Ave. Duration
- 7h 58m
- When
- Saturday
- Estimated price
- $210–900
Flights from Mcghee Tyson Airport to Oakland International Airport via Las Vegas
- Ave. Duration
- 8h 9m
- When
- Thursday
- Estimated price
- $200–850
Flights from Mcghee Tyson Airport to Norman Y. Mineta San José International Airport via Denver
- Ave. Duration
- 7h 30m
- When
- Sunday
- Estimated price
- $190–850
Flights from Mcghee Tyson Airport to Norman Y. Mineta San José International Airport via Dallas
- Ave. Duration
- 8h 35m
- When
- Tuesday and Wednesday
- Estimated price
- $200–850
Flights from Mcghee Tyson Airport to Norman Y. Mineta San José International Airport via Nashville
- Ave. Duration
- 12h 5m
- When
- Every day
- Estimated price
- $190–850
Rome2Rio's guide to Amtrak
Contact DetailsContact Details
- Phone
- +1 800-872-7245
- Website
- Amtrak
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $50–120
- Website
- Amtrak
Train from Chicago Union Station to Martinez
- Ave. Duration
- 2d 4h
- Frequency
- Once daily
- Estimated price
- $600–1,400
- Website
- Amtrak
Train from Ny Moynihan Train Hall At Penn Station to Chicago Union Station
- Ave. Duration
- 19h 32m
- Frequency
- Once daily
- Estimated price
- $240–550
- Website
- Amtrak
Train from Chicago Union Station to Martinez
- Ave. Duration
- 2d 4h
- Frequency
- Once daily
- Estimated price
- $600–1,400
- Website
- Amtrak
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- Wanda Coach
Bus from Knoxville to Jackson
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $50–75
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $50–75
Bus from Knoxville to Jackson
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $50–75
- Website
- Wanda Coach
- Book at
- GotoBus.com
- Adult One Way
- $50–75
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Booking & Getting There
Yes, the driving distance between Knoxville to Santa Rosa is 2526 miles. It takes approximately 40h 2m to drive from Knoxville to Santa Rosa.
There are 286+ hotels available in Santa Rosa.



