There are 6 ways to get from Knoxville to Orlando by plane, train, car or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly Knoxville to Orlando Sanford, train  •  3 h 41 min

  1. Fly from Knoxville (TYS) to Orlando Sanford (SFB) TYS - SFB
  2. Take the train from Sanford to Church Street

$154 - $286

Cheapest option

Bus, Megabus  •  13 h 53 min

  1. Take the bus from Knoxville, Tn to Atlanta, Ga 1109 / ...
  2. Take the Megabus from Midtown Atlanta to Orlando

$67 - $128

4 alternative options

Fly Knoxville to Orlando  •  5 h 15 min

  1. Fly from Knoxville (TYS) to Orlando (MCO) TYS - MCO

$252 - $1,073

Drive to Asheville, fly to Orlando  •  5 h 30 min

  1. Drive from Knoxville to Asheville
  2. Fly from Asheville (AVL) to Orlando (MCO) AVL - MCO

$247 - $453

Bus  •  13 h

  1. Take the bus from Knoxville, Tn to Atlanta, Ga 1109 / ...
  2. Take the bus from Atlanta, Ga to Orlando, Fl 1125 / ...

$71 - $182

Drive  •  10 h 41 min

  1. Drive from Knoxville to Orlando 645 miles

$60 - $95

Questions & Answers

The cheapest way to get from Knoxville to Orlando is to drive which costs $60 - $95 and takes 10 h 41 min.

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The quickest way to get from Knoxville to Orlando is to fly and train which costs $150 - $290 and takes 3 h 41 min.

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No, there is no direct bus from Knoxville to Orlando. However, there are services departing from Knoxville, Tn and arriving at Orlando, Fl via Atlanta, Ga. The journey, including transfers, takes approximately 13 h.

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The distance between Knoxville and Orlando is 537 miles. The road distance is 645 miles.

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The best way to get from Knoxville to Orlando without a car is to bus which takes 13 h and costs $70 - $190.

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It takes approximately 3 h 41 min to get from Knoxville to Orlando, including transfers.

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Knoxville to Orlando bus services, operated by Greyhound USA, depart from Knoxville, Tn station.

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The best way to get from Knoxville to Orlando is to fly which takes 5 h 15 min and costs $250 - $1,100. Alternatively, you can bus, which costs $70 - $190 and takes 13 h.

Mode details

The quickest flight from Knoxville Airport to Orlando Sanford Airport is the direct flight which takes 1 h 35 min.

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Knoxville to Orlando bus services, operated by Greyhound USA, arrive at Orlando, Fl station.

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Map of how to get from Knoxville to Orlando.
Launch map view
  • Distance: 537 miles
  • Duration: 3 h 41 min

What companies run services between Knoxville, TN, USA and Orlando, FL, USA?

Delta, American Airlines and United Airlines fly from Knoxville to Orlando hourly. Alternatively, you can take a bus from Knoxville to Orlando via Atlanta, Ga in around 13 h.

Airlines
Delta
Website
delta.com
Flights from Knoxville to Orlando via Atlanta
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$190 - $1,000
Flights from Knoxville to Orlando via Detroit
Ave. Duration
5 h 18 min
When
Every day
Estimated price
$260 - $1,200
Flights from Asheville to Orlando via Atlanta
Ave. Duration
3 h 50 min
When
Every day
Estimated price
$470 - $850
American Airlines
Website
aa.com
Flights from Knoxville to Orlando via Charlotte
Ave. Duration
5 h 20 min
When
Every day
Estimated price
$210 - $1,100
Flights from Knoxville to Orlando via Philadelphia
Ave. Duration
5 h 58 min
When
Every day
Estimated price
$280 - $1,200
Flights from Asheville to Orlando via Charlotte
Ave. Duration
3 h 55 min
When
Every day
Estimated price
$460 - $850
United Airlines
Website
united.com
Flights from Knoxville to Orlando via Washington Dulles
Ave. Duration
4 h 52 min
When
Every day
Estimated price
$270 - $1,200
Flights from Knoxville to Orlando via Chicago O'Hare
Ave. Duration
5 h 34 min
When
Every day
Estimated price
$290 - $1,300
Allegiant Air
Website
allegiantair.com
Flights from Knoxville to Orlando Sanford
Ave. Duration
1 h 35 min
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$110 - $380
Spirit Airlines
Website
spirit.com
Flights from Asheville to Orlando
Ave. Duration
1 h 43 min
When
Monday, Friday and Saturday
Estimated price
$95 - $430
Train operators
SunRail
Website
sunrail.com
Train from Sanford to Church Street
Ave. Duration
45 min
Frequency
Hourly
Estimated price
$2 - $4
Schedules at
sunrail.com
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Knoxville, Tn to Atlanta, Ga
Ave. Duration
4 h 30 min
Frequency
Every 30 minutes
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $45
Flexible
$45 - $65
Bus from Atlanta, Ga to Orlando, Fl
Ave. Duration
8 h
Frequency
Hourly
Estimated price
$45 - $120
Website
greyhound.com
Economy
$45 - $75
Flexible
$85 - $120

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More Questions & Answers

Yes, the driving distance between Knoxville to Orlando is 645 miles. It takes approximately 10 h 41 min to drive from Knoxville to Orlando.

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Allegiant Air offers flights from Knoxville Airport to Orlando Sanford Airport.

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Book your Knoxville to Orlando bus tickets online with Greyhound and Greyhound.

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There are 1015+ hotels available in Orlando. Prices start at $72 USD per night.

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The best way to get from Knoxville to Knoxville Airport is to taxi which takes 18 min and costs $55 - $70.

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