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There are 7 ways to get from Knoxville to Orlando by plane, train, bus, night bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly to Orlando  •  3h 41m

  1. Fly from Knoxville (TYS) to Orlando (MCO) TYS - MCO

$172 - $623

Cheapest option

Bus, Megabus  •  13h 42m

  1. Take the bus from Knoxville, Tn to Atlanta, Ga 1109 / ...
  2. Take the Megabus from Midtown Atlanta to Orlando

$67 - $128

5 alternative options

Fly to Orlando Sanford, train  •  3h 40m

  1. Fly from Knoxville (TYS) to Orlando Sanford (SFB) TYS - SFB
  2. Take the train from Sanford to Church Street

$154 - $286

Fly to Daytona Beach, bus  •  6h 53m

  1. Fly from Knoxville (TYS) to Daytona Beach (DAB) TYS - DAB
  2. Take the bus from Daytona International Speedway to Skyview Plaza Orlando

$262 - $1,012

Bus  •  15h 40m

  1. Take the bus from Knoxville, Tn to Atlanta, Ga 1109 / ...
  2. Take the bus from Atlanta, Ga to Orlando, Fl 1119 / ...

$71 - $182

Bus, night bus  •  13h 30m

  1. Take the bus from Knoxville, Tn to Atlanta, Ga 1109 / ...
  2. Take the night bus from Atlanta, Ga to Orlando, Fl 3735

$71 - $182

Drive  •  10h 41m

  1. Drive from Knoxville to Orlando 645 miles

$60 - $95

Questions & Answers

The cheapest way to get from Knoxville to Orlando is to drive which costs $60 - $95 and takes 10h 41m.

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The quickest way to get from Knoxville to Orlando is to fly and train which costs $150 - $290 and takes 3h 40m.

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No, there is no direct bus from Knoxville to Orlando. However, there are services departing from Knoxville, Tn and arriving at Orlando, Fl via Atlanta, Ga. The journey, including transfers, takes approximately 15h 40m.

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The distance between Knoxville and Orlando is 537 miles. The road distance is 645 miles.

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The best way to get from Knoxville to Orlando without a car is to bus and Megabus which takes 13h 42m and costs $65 - $130.

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It takes approximately 3h 41m to get from Knoxville to Orlando, including transfers.

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Knoxville to Orlando bus services, operated by Greyhound USA, depart from Knoxville, Tn station.

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The best way to get from Knoxville to Orlando is to fly which takes 3h 41m and costs $170 - $650. Alternatively, you can bus and Megabus, which costs $65 - $130 and takes 13h 42m.

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The quickest flight from Knoxville Airport to Orlando Airport is the direct flight which takes 1h 48m.

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Knoxville to Orlando bus services, operated by Greyhound USA, arrive at Orlando, Fl station.

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Map of how to get from Knoxville to Orlando.
Launch map view
  • Distance: 537 miles
  • Duration: 3h 41m

What companies run services between Knoxville, TN, USA and Orlando, FL, USA?

Frontier Airlines, Delta and American Airlines fly from Knoxville to Orlando hourly. Alternatively, you can take a bus from Knoxville to Orlando via Atlanta, Ga, Five Points Station, Civic Center Station, Midtown Atlanta, Orlando, and E Colonial Drive And N Semoran Boulevard in around 13h 42m.

Airlines
Delta
Website
delta.com
Flights from Knoxville to Orlando via Atlanta
Ave. Duration
3h 49m
When
Every day
Estimated price
$190 - $1,000
Flights from Knoxville to Daytona Beach via Atlanta
Ave. Duration
4h 13m
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$160 - $900
American Airlines
Website
aa.com
Flights from Knoxville to Orlando via Charlotte
Ave. Duration
4h 5m
When
Monday to Saturday
Estimated price
$210 - $1,100
Flights from Knoxville to Daytona Beach via Charlotte
Ave. Duration
4h 24m
When
Every day
Estimated price
$180 - $900
Flights from Knoxville to Daytona Beach via Reagan Washington, Charlotte
Ave. Duration
7h
When
Saturday and Sunday
Estimated price
$230 - $1,000
Frontier Airlines
Website
flyfrontier.com
Flights from Knoxville to Orlando
Ave. Duration
1h 48m
When
Monday and Friday
Estimated price
$110 - $550
Allegiant Air
Website
allegiantair.com
Flights from Knoxville to Orlando Sanford
Ave. Duration
1h 34m
When
Monday, Wednesday, Thursday, Friday, Saturday and Sunday
Estimated price
$110 - $380
Train operators
SunRail
Website
sunrail.com
Train from Sanford to Church Street
Ave. Duration
45m
Frequency
Hourly
Estimated price
$2 - $4
Schedules at
sunrail.com
Bus operators
Escot Bus Lines
Phone
+1-888-571-7778
Website
escotbuslines.com
Bus from Daytona International Speedway to Skyview Plaza Orlando
Ave. Duration
1h 15m
Frequency
Twice a week
Estimated price
$42
Schedules at
escotbuslines.com
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Knoxville, Tn to Atlanta, Ga
Ave. Duration
4h 30m
Frequency
5 times a day
Estimated price
$26 - $65
Website
greyhound.com
Economy
$26 - $45
Flexible
$45 - $65
Bus from Atlanta, Ga to Orlando, Fl
Ave. Duration
10h 10m
Frequency
4 times a day
Estimated price
$45 - $120
Website
greyhound.com
Economy
$45 - $75
Flexible
$90 - $120

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Yes, the driving distance between Knoxville to Orlando is 645 miles. It takes approximately 10h 41m to drive from Knoxville to Orlando.

Get driving directions

Frontier Airlines, American Airlines and Delta offer flights from Knoxville Airport to Orlando Airport.

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Book your Knoxville to Orlando bus tickets online with Greyhound and Greyhound.

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There are 1044+ hotels available in Orlando. Prices start at $92 USD per night.

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The best way to get from Knoxville to Knoxville Airport is to taxi which takes 18m and costs $55 - $70.

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