There are 4 ways to get from Knoxville to Memphis by plane, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  4 h 25 min

  1. Fly from Knoxville (TYS) to Memphis (MEM) TYS - MEM

$239 - $869

Cheapest option

Megabus, bus  •  11 h 56 min

  1. Take the Megabus from Knoxville to Chattanooga
  2. Take the bus from Chattanooga to Nashville, TN
  3. Take the bus from Nashville, Tn to Memphis, Tn

$55 - $111

2 alternative options

Bus  •  12 h 4 min

  1. Take the bus from Knoxville to Atlanta via Philadelphia
  2. Take the bus from Atlanta, Ga to Memphis, Tn 3861 / ...

$65 - $136

Drive  •  6 h 24 min

  1. Drive from Knoxville to Memphis 389.6 miles

$35 - $55

What companies run services between Knoxville, TN, USA and Memphis, TN, USA?

Delta, American Airlines and two other airlines fly from Knoxville to Memphis hourly. Alternatively, you can take a bus from Knoxville to Memphis via Chattanooga, Nashville, TN, Nashville, TN, and Nashville, Tn in around 11 h 56 min.

Airlines
Delta
Website
delta.com
Flights from Knoxville to Memphis via Atlanta
Ave. Duration
4 h 12 min
When
Every day
Estimated price
$170 - $900
Flights from Knoxville to Memphis via Detroit
Ave. Duration
5 h 10 min
When
Every day
Estimated price
$210 - $1,000
American Airlines
Website
aa.com
Flights from Knoxville to Memphis via Charlotte
Ave. Duration
4 h 33 min
When
Every day
Estimated price
$200 - $950
Flights from Knoxville to Memphis via Chicago O'Hare
Ave. Duration
5 h
When
Every day
Estimated price
$220 - $1,000
Flights from Knoxville to Memphis via Dallas/Ft.Worth
Ave. Duration
5 h 44 min
When
Every day
Estimated price
$240 - $1,100
United Airlines
Website
united.com
Flights from Knoxville to Memphis via Chicago O'Hare
Ave. Duration
5 h 22 min
When
Every day
Estimated price
$230 - $1,100
Flights from Knoxville to Memphis via Houston
Ave. Duration
5 h 25 min
When
Every day
Estimated price
$250 - $1,100
Flights from Knoxville to Memphis via Newark
Ave. Duration
6 h 14 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$270 - $1,200
Allegiant Air
Website
allegiantair.com
Flights from Knoxville to Memphis via St. Petersburg
Ave. Duration
5 h 25 min
When
Thursday and Sunday
Estimated price
$180 - $800
Bus operators
Megabus
Phone
877-462-6342
Website
us.megabus.com
Bus from Knoxville to Chattanooga
Ave. Duration
2 h
Frequency
3 times a day
Estimated price
$12 - $22
Schedules at
us.megabus.com
Bus from Chattanooga to Nashville, TN
Ave. Duration
2 h 37 min
Frequency
Twice daily
Estimated price
$14 - $25
Schedules at
us.megabus.com
Bus from Knoxville to Atlanta
Ave. Duration
3 h 55 min
Frequency
3 times a day
Estimated price
$22 - $35
Schedules at
us.megabus.com
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Nashville, Tn to Memphis, Tn
Ave. Duration
4 h 45 min
Frequency
Hourly
Estimated price
$25 - $60
Website
greyhound.com
Economy
$25 - $40
Flexible
$45 - $60
Bus from Atlanta, Ga to Memphis, Tn
Ave. Duration
7 h 15 min
Frequency
Hourly
Estimated price
$40 - $100
Website
greyhound.com
Economy
$40 - $65
Flexible
$75 - $100

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Questions & Answers

How far is it from Knoxville to Memphis?

The distance between Knoxville and Memphis is 562 km. The road distance is 623 km.

What is the cheapest way to get from Knoxville to Memphis?

The cheapest way to get from Knoxville to Memphis is to drive which costs $35 - $55 and takes 6 h 24 min.

What is the fastest way to get from Knoxville to Memphis?

The quickest way to get from Knoxville to Memphis is to fly which takes 4 h 25 min and costs $230 - $900.

Is there a direct bus between Knoxville and Memphis?

No, there is no direct bus from Knoxville to Memphis. However, there are services departing from Knoxville and arriving at Memphis, Tn via Chattanooga, Nashville, TN and Nashville, Tn. The journey, including transfers, takes approximately 11 h 56 min.

How long does it take to get from Knoxville to Memphis?

It takes approximately 4 h 25 min to get from Knoxville to Memphis, including transfers.