There are 4 ways to get from Knoxville to Kansas City by plane, bus, train or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Fly  •  6 h 4 min

  1. Fly from Knoxville (TYS) to Kansas City (MCI) TYS - MCI

$239 - $969

Cheapest option

Bus  •  19 h 34 min

  1. Take the bus from Knoxville, Tn to Lexington, Ky
  2. Take the bus from Lexington, KY to Evansville
  3. Take the bus from Evansville, In to St Louis, Mo
  4. Take the bus from St Louis, Mo to Kansas City, Mo

$119 - $243

2 alternative options

Bus, train  •  23 h 29 min

  1. Take the bus from Knoxville, Tn to Lexington, Ky
  2. Take the bus from Lexington, KY to Louisville, KY
  3. Take the bus from Louisville, KY to Indianapolis, IN - Amtrak
  4. Take the train from Indianapolis Amtrak to Chicago Union Station
  5. Take the train from Chicago Union Station to Kansas City Amtrak

$177 - $483

Drive  •  12 h 5 min

  1. Drive from Knoxville to Kansas City 736.8 miles

$70 - $110

Questions & Answers

The cheapest way to get from Knoxville to Kansas City is to drive which costs $70 - $110 and takes 12 h 5 min.

More details

The quickest way to get from Knoxville to Kansas City is to fly which costs $230 - $1,000 and takes 6 h 4 min.

More details

No, there is no direct bus from Knoxville to Kansas City. However, there are services departing from Knoxville, Tn and arriving at Kansas City, Mo via Lexington, KY, Evansville, In and St Louis, Mo. The journey, including transfers, takes approximately 19 h 34 min.

More details

The distance between Knoxville and Kansas City is 626 miles. The road distance is 736.8 miles.

Get driving directions

The best way to get from Knoxville to Kansas City without a car is to bus which takes 19 h 34 min and costs $110 - $250.

More details

It takes approximately 6 h 4 min to get from Knoxville to Kansas City, including transfers.

More details

Knoxville to Kansas City bus services, operated by Greyhound USA, depart from Knoxville, Tn station.

More details

The best way to get from Knoxville to Kansas City is to fly which takes 6 h 4 min and costs $230 - $1,000. Alternatively, you can bus, which costs $110 - $250 and takes 19 h 34 min.

Mode details

There is no direct flight from Knoxville Airport to Kansas City Airport. The quickest flight takes 4 h 15 min and has one stopover.

Search flights

Knoxville to Kansas City bus services, operated by Greyhound USA, arrive at Kansas City, Mo station.

More details

Map of how to get from Knoxville to Kansas City.
Launch map view
  • Distance: 626.1 miles
  • Duration: 6 h 4 min

What companies run services between Knoxville, TN, USA and Kansas City, MO, USA?

United Airlines, Delta and American Airlines fly from Knoxville to Kansas City hourly. Alternatively, you can take a bus from Knoxville to Kansas City via Lexington, Ky, Lexington, KY, Evansville, Evansville, In, and St Louis, Mo in around 19 h 34 min.

Airlines
American Airlines
Website
aa.com
Flights from Knoxville to Kansas City via Chicago O'Hare
Ave. Duration
5 h 16 min
When
Every day
Estimated price
$200 - $900
Flights from Knoxville to Kansas City via Dallas/Ft.Worth
Ave. Duration
5 h 43 min
When
Every day
Estimated price
$220 - $950
Flights from Knoxville to Kansas City via Charlotte
Ave. Duration
5 h 37 min
When
Every day
Estimated price
$210 - $950
United Airlines
Website
united.com
Flights from Knoxville to Kansas City via Chicago O'Hare
Ave. Duration
4 h 55 min
When
Every day
Estimated price
$210 - $950
Flights from Knoxville to Kansas City via Washington Dulles
Ave. Duration
5 h 8 min
When
Every day
Estimated price
$240 - $1,100
Flights from Knoxville to Kansas City via Denver
Ave. Duration
5 h 56 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$260 - $1,200
Flights from Knoxville to Kansas City via Houston
Ave. Duration
6 h 12 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$240 - $1,100
Delta
Website
delta.com
Flights from Knoxville to Kansas City via Atlanta
Ave. Duration
4 h 53 min
When
Every day
Estimated price
$180 - $900
Flights from Knoxville to Kansas City via Detroit
Ave. Duration
4 h 49 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$200 - $950
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Indianapolis Amtrak to Chicago Union Station
Ave. Duration
5 h
Frequency
Once daily
Estimated price
$40 - $100
Website
amtrak.com
Coach Seat
$40 - $60
Flexi Coach Seat
$70 - $110
Business Coach Seat
$70 - $100
Room
$200 - $280
Train from Chicago Union Station to Kansas City Amtrak
Ave. Duration
7 h 10 min
Frequency
Twice daily
Estimated price
$65 - $190
Website
amtrak.com
Coach Seat
$65 - $100
Flexi Coach Seat
$120 - $180
Business Coach Seat
$130 - $190
Room
$290 - $410
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Knoxville, Tn to Lexington, Ky
Ave. Duration
3 h 49 min
Frequency
Every 30 minutes
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from Evansville, In to St Louis, Mo
Ave. Duration
3 h 55 min
Frequency
Hourly
Estimated price
$22 - $55
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $55
Bus from St Louis, Mo to Kansas City, Mo
Ave. Duration
4 h 25 min
Frequency
Hourly
Estimated price
$29 - $70
Website
greyhound.com
Economy
$29 - $45
Flexible
$50 - $70
Hoosier Ride
Phone
800-544-2383
Website
hoosierride.com
Bus from Lexington, KY to Evansville
Ave. Duration
5 h 30 min
Frequency
Twice daily
Estimated price
$45 - $65
Book at
hoosierride.com
Bus from Lexington, KY to Louisville, KY
Ave. Duration
1 h 20 min
Frequency
4 times a day
Estimated price
$21 - $100
Book at
hoosierride.com
Bus from Louisville, KY to Indianapolis, IN
Ave. Duration
3 h 30 min
Frequency
Once daily
Estimated price
$28 - $40
Book at
hoosierride.com
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Bus from Louisville, KY to Indianapolis, IN - Amtrak
Ave. Duration
2 h 10 min
Frequency
Twice daily
Website
amtrak.com

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.