There are 3 ways to get from Knoxville to Greenville by bus, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

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Bus  •  4 h 40 min

  1. Take the bus from Knoxville, Tn to Asheville, Nc 4840
  2. Take the bus from Asheville to Greenville Asheville

$35 - $68

2 alternative options

Drive  •  3 h 8 min

  1. Drive from Knoxville to Greenville 170 miles

$16 - $24

Fly, bus  •  4 h 24 min

  1. Fly from Knoxville (TYS) to Charlotte (CLT) TYS - CLT
  2. Take the bus from Charlotte, NC to Greenville, SC

Questions & Answers

No, there is no direct bus from Knoxville to Greenville. However, there are services departing from Knoxville, Tn and arriving at Greenville via Asheville. The journey, including transfers, takes approximately 4 h 40 min.

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The distance between Knoxville and Greenville is 116 miles. The road distance is 170 miles.

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The best way to get from Knoxville to Greenville without a car is to bus which takes 4 h 40 min and costs .

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It takes approximately 4 h 40 min to get from Knoxville to Greenville, including transfers.

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Knoxville to Greenville bus services, operated by Greyhound USA, depart from Knoxville, Tn station.

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The quickest flight from Knoxville Airport to Charlotte Airport is the direct flight which takes 1 h 6 min.

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Knoxville to Greenville bus services, operated by South Eastern Stages, arrive at Greenville station.

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Yes, the driving distance between Knoxville to Greenville is 170 miles. It takes approximately 3 h 8 min to drive from Knoxville to Greenville.

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Delta and American Airlines offer flights from Knoxville Airport to Charlotte Airport.

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There are 83+ hotels available in Greenville. Prices start at $69 USD per night.

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Map of how to get from Knoxville to Greenville.
Launch map view
  • Distance: 115.8 miles
  • Duration: 4 h 40 min

What companies run services between Knoxville, TN, USA and Greenville, SC, USA?

You can take a bus from Knoxville to Greenville via Asheville, Nc and Asheville in around 4 h 40 min.

Airlines
American Airlines
Website
aa.com
Flights from Knoxville to Charlotte
Ave. Duration
1 h 20 min
When
Every day
Estimated price
$130 - $750
Delta
Website
delta.com
Flights from Knoxville to Charlotte via Atlanta
Ave. Duration
3 h 11 min
When
Monday to Saturday
Estimated price
$130 - $750
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Knoxville, Tn to Asheville, Nc
Ave. Duration
2 h 20 min
Frequency
Every 2 hours
Estimated price
$17 - $40
Website
greyhound.com
Economy
$17 - $26
Flexible
$30 - $40
Wanda Coach
Phone
6466307186
Email
help@wandacoach.com
Website
wandacoach.com
Bus from Charlotte, NC to Greenville, SC
Ave. Duration
1 h 45 min
Frequency
Every 4 hours
Schedules at
wandacoach.com

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More Questions & Answers

The best way to get from Knoxville to Knoxville Airport is to taxi which takes 18 min and costs .

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