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How to get fromKnoxville to Cape Codby plane, bus, train, car, shuttle or taxi

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There are 6 ways to get from Knoxville to Cape Cod by plane, bus, train, car, shuttle, or taxi

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Barnstable Municipal Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Barnstable Municipal Airport (HYA)plane plane TYS - HYA
    5h 30m
    $437–1,257
  2. Drive 948.6 mi

    cheapest
    1. Drive from Knoxville to Cape Codcar car 948.6 mi
    16h 53m
    $174–251
  3. Bus, train

    1. Take the bus from Knoxville, TN to New York, NYbus bus
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Bostontrain train
    3. Take the bus from Boston South Station to Barnstablebus bus
    20h 41m
    $225–1,003
  4. Drive, shuttle, taxi, bus, train

    1. Drive from Knoxville to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Bristol Exit 5 Park & Ride Lottaxi taxi
    4. Take the bus from Bristol Exit 5 Park & Ride Lot to Christiansburgbus bus
    5. Take the bus from Exit 118 - Park and Ride to Roanoke Campbell Courtbus bus Swb
    6. Take the train from Roanoke to Bostontrain train
    7. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    31h 11m
    $390–897
  5. Fly to Boston Logan Airport, bus

    1. Fly from Mcghee Tyson Airport (TYS) to Boston Logan Airport (BOS)plane plane TYS - BOS
    2. Take the bus from Logan International Airport to Hyannis Transportation Centerbus bus
    6h 42m
    $218–810
  6. Drive, shuttle, taxi, bus, train via Washington

    1. Drive from Chilhowee at Holston to Hot Springscar car
    2. Take a shuttle bus from Hot Springs to Black Bear Resortshuttle bus
    3. Take the taxi from Black Bear Resort to Bristol Exit 5 Park & Ride Lottaxi taxi
    4. Take the bus from Bristol Exit 5 Park & Ride Lot to Washington Union Stationbus bus
    5. Take the train from Washington Union Station to Bostontrain train
    6. Take the bus from Boston South Buses to Hyannis Transportation Centerbus bus
    25h 1m
    $385–1,279

Mcghee Tyson Airport (TYS) to Barnstable Municipal Airport (HYA) flights

Calendar23Weekly Planes
Duration6h 2mAverage Duration
Ticket$180Cheapest Price
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Questions & Answers

What companies run services between Knoxville, TN, USA and Cape Cod, MA, USA?

American Airlines, Allegiant Air, and two other airlines fly from Mcghee Tyson Airport (TYS) to Barnstable Municipal Airport (HYA) 3 times a day.

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