There are 6 ways to get from Knoxville to Appleton by plane, bus (Greyhound, Flixbus), car, bus, train, or bus (Amtrak, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Appleton International Airport
best- Fly from Mcghee Tyson Airport (TYS) to Appleton International Airport (ATW)plane TYS - ATW
4h 38m$171–640Drive 717.1 mi
cheapest- Drive from Knoxville to Appletoncar 717.1 mi
12h 30m$131–189Bus
- Take the bus from Knoxville to Nashvillebus Nyc
- Take the bus from Nashville Bus Station to Chicago Bus Stationbus
- Take the bus from Chicago Bus Station to Appleton Transit Centerbus
20h 11m$218–374Fly to Green Bay
- Fly from Mcghee Tyson Airport (TYS) to Green Bay (GRB)plane TYS - GRB
6h 6m$187–660Bus, train
- Take the bus from Knoxville to Nashvillebus Nyc
- Take the bus from Nashville to Chicago Union Stationbus
- Take the train from Chicago Union Station to Milwaukeetrain
- Take the bus from Milwaukee to Appleton Amtrak Stationbus
20h 34m$249–439Bus via Memphis
- Take the bus from Knoxville to Jacksonbus Nyc
- Take the bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphisbus
- Take the bus from Tornado Bus Co - West Memphis to Water & Chicago - Circle Kbus
- Take the bus from Milwaukee to Appleton Amtrak Stationbus
24h 36m$292–605
Mcghee Tyson Airport (TYS) to Appleton International Airport (ATW) flights
Questions & Answers
The cheapest way to get from Knoxville to Appleton is to drive which costs $130 - $190 and takes 12h 30m.
The fastest way to get from Knoxville to Appleton is to fly which takes 4h 38m and costs $170 - $650.
The distance between Knoxville and Appleton is 652 miles. The road distance is 721.3 miles.
The best way to get from Knoxville to Appleton without a car is to bus which takes 20h 11m and costs $210 - $380.
It takes approximately 4h 38m to get from Knoxville to Appleton, including transfers.
The best way to get from Knoxville to Appleton is to fly which takes 4h 38m and costs $170 - $650. Alternatively, you can bus, which costs $210 - $380 and takes 20h 11m.
Appleton is 1h behind Knoxville. It is currently 11:18 AM in Knoxville and 10:18 AM in Appleton.
Yes, the driving distance between Knoxville to Appleton is 721 miles. It takes approximately 12h 30m to drive from Knoxville to Appleton.
There are 71+ hotels available in Appleton.
What companies run services between Knoxville, TN, USA and Appleton, WI, USA?
Delta, United Airlines, and American Airlines fly from Mcghee Tyson Airport (TYS) to Appleton International Airport (ATW) every 2 hours. Alternatively, you can take a vehicle from Knoxville to Appleton Transit Center via Knoxville, Nashville, Charlotte Pike & Lellyett St Eb, Central 5Th Ave - Bay 1, Central 4Th Ave - Bay 13, Fulton Station Outbound, Nashville Bus Station, and Chicago Bus Station in around 20h 11m.
- Website
- delta.com
Flights from Mcghee Tyson Airport to Appleton International Airport via Detroit
- Ave. Duration
- 5h 49m
- When
- Every day
- Estimated price
- $100–600
Flights from Mcghee Tyson Airport to Appleton International Airport via Atlanta
- Ave. Duration
- 4h 34m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Mcghee Tyson Airport to Appleton International Airport via Minneapolis
- Ave. Duration
- 6h 2m
- When
- Every day
- Estimated price
- $130–700
Flights from Mcghee Tyson Airport to Green Bay via Detroit
- Ave. Duration
- 5h 14m
- When
- Monday, Tuesday, Wednesday, Thursday, Saturday, and Sunday
- Estimated price
- $100–600
Flights from Mcghee Tyson Airport to Green Bay via Atlanta
- Ave. Duration
- 5h 14m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $120–650
Flights from Mcghee Tyson Airport to Green Bay via Minneapolis
- Ave. Duration
- 5h 58m
- When
- Every day
- Estimated price
- $130–700
- Website
- united.com
Flights from Mcghee Tyson Airport to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 5h 16m
- When
- Every day
- Estimated price
- $95–550
Flights from Mcghee Tyson Airport to Green Bay via Chicago O'Hare
- Ave. Duration
- 5h 22m
- When
- Every day
- Estimated price
- $95–550
- Website
- aa.com
Flights from Mcghee Tyson Airport to Appleton International Airport via Chicago O'Hare
- Ave. Duration
- 7h 3m
- When
- Every day
- Estimated price
- $95–550
Flights from Mcghee Tyson Airport to Appleton International Airport via Charlotte
- Ave. Duration
- 6h 26m
- When
- Every day
- Estimated price
- $120–650
Flights from Mcghee Tyson Airport to Green Bay via Chicago O'Hare
- Ave. Duration
- 6h 7m
- When
- Every day
- Estimated price
- $95–550
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Chicago Union Station to Milwaukee
- Ave. Duration
- 1h 29m
- Frequency
- Every 4 hours
- Estimated price
- $23–55
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Knoxville to Nashville
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $40–60
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $40–60
Bus from Knoxville to Jackson
- Ave. Duration
- 5h 30m
- Frequency
- Once daily
- Estimated price
- $50–75
- Website
- https://www.wandacoach.com
- Book at
- https://www.gotobus.com/wanda-travel/
- Adult One Way
- $50–75
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Nashville Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 40m
- Frequency
- 4 times a day
- Estimated price
- $80–160
- Website
- https://www.greyhound.com/
Bus from Nashville to Chicago Union Station
- Ave. Duration
- 9h 45m
- Frequency
- Twice daily
- Estimated price
- $80–160
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Nashville Bus Station to Chicago Bus Station
- Ave. Duration
- 9h 25m
- Frequency
- 3 times a day
- Estimated price
- $60–110
- Schedules at
- flixbus.com
Bus from Chicago Bus Station to Appleton Transit Center
- Ave. Duration
- 4h 30m
- Frequency
- 5 times a week
- Estimated price
- $25–45
- Schedules at
- flixbus.com
Bus from Milwaukee to Appleton Amtrak Station
- Ave. Duration
- 2h 10m
- Frequency
- 5 times a week
- Estimated price
- $13–23
- Schedules at
- flixbus.com
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Nashville to Chicago Union Station
- Ave. Duration
- 9h 40m
- Frequency
- Twice daily
- Estimated price
- $55–85
- Website
- https://www.amtrak.com/home.html
- Adult
- $55–85
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Milwaukee to Appleton Amtrak Station
- Ave. Duration
- 2h 24m
- Frequency
- Twice daily
- Estimated price
- $30–55
- Website
- https://www.amtrak.com/home.html
- Phone
- 920 496 3600
- Website
- golamers.com
Bus from Milwaukee to Appleton Amtrak Station
- Ave. Duration
- 2h 30m
- Frequency
- Once daily
- Estimated price
- $23–26
- Schedules at
- golamers.com
- Phone
- +1 888 358 6762
- info@tornadobus.com
- Website
- tornadobus.com
Bus from El Mezcal Grocery - Jackson, TN to Tornado Bus Co - West Memphis
- Ave. Duration
- 1h 44m
- Frequency
- 3 times a week
- Estimated price
- $40–140
- Schedules at
- tornadobus.com
- Adults 11-59
- $40–140
Bus from Tornado Bus Co - West Memphis to Water & Chicago - Circle K
- Ave. Duration
- 11h 25m
- Frequency
- Once daily
- Estimated price
- $100–230
- Schedules at
- tornadobus.com
- Adults 11-59
- $100–230
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