There are 6 ways to get from Knoxville to Afton by plane, night bus, bus, train or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Recommended option
Fly to Binghamton
-
Fly from Knoxville (TYS) to Binghamton (BGM)
Cheapest option
Bus
-
Take the bus from Knoxville to New York City
-
Take the bus from New York to Binghamton
4 alternative options
Fly to Scranton/Wilkes-Barre, night bus
-
Fly from Knoxville (TYS) to Scranton/Wilkes-Barre (AVP)
-
Take the night bus from Scranton to Binghamton
Bus via Knoxville
-
Take the bus from Knoxville to New York, NY
-
Take the bus from New York to Binghamton
Bus, train
-
Take the bus from Knoxville to Christiansburg, VA - 2370 Roanoke St
-
Take the bus from Exit 118 - Park and Ride to Roanoke Amtrak Station
-
Take the train from Roanoke to New York Penn Station
-
Take the bus from New York, NY to Binghamton, NY
Drive
-
Drive from Knoxville to Afton
Travel safe during COVID-19
Rules to follow in United States
2m
Recommended
Travel within United States
Observe COVID-19 safety rules
COVID-19 help in United States
If you need help, visit the national COVID-19 website or call the COVID-19 Helpline 800-232-4636
Frequently Asked Questions
Yes, travel within United States is currently allowed.
Explore travel optionsDomestic travel is not restricted, but some conditions may apply
- Face masks are recommended
- There is a social distancing requirement of 2 metres
- Observe COVID-19 safety rules
The national COVID-19 helpline number in Afton is 800-232-4636.
Wearing a face mask on public transport in Afton is recommended.
The social distance requirement in Afton is 2 metres.
Make yourself known to an official member of staff and/or call the national coronavirus helpline number on 800-232-4636.
Last updated: 9 May 2023
Exceptions may apply, for full details: Centers for Disease control and prevention (CDC).
We're working around the clock to bring you the latest COVID-19 travel updates.
This information is compiled from official sources. To the best of our knowledge, it is correct as of the last update.
Visit Rome2Rio travel advice for general help.
Questions & Answers
The cheapest way to get from Knoxville to Afton is to drive which costs $130 - $200 and takes 12h 25m.
The fastest way to get from Knoxville to Afton is to fly which takes 5h 14m and costs $270 - $470.
The distance between Knoxville and Afton is 628 miles. The road distance is 741.9 miles.
The best way to get from Knoxville to Afton without a car is to bus which takes 19h 55m and costs $150 - $290.
It takes approximately 5h 14m to get from Knoxville to Afton, including transfers.
The best way to get from Knoxville to Afton is to fly which takes 5h 14m and costs $270 - $470. Alternatively, you can bus, which costs $150 - $290 and takes 19h 55m.
There is no direct flight from Knoxville Airport to Binghamton Airport. The quickest flight takes 4h 14m and has one stopover.
Yes, the driving distance between Knoxville to Afton is 742 miles. It takes approximately 12h 25m to drive from Knoxville to Afton.
Delta offers flights from Knoxville Airport to Binghamton Airport.
There are two+ hotels available in Afton. Prices start at $100 USD per night.

- Distance: 627.7 miles
- Duration: 5h 14m
What companies run services between Knoxville, TN, USA and Afton, NY, USA?
Delta and American Airlines fly from Knoxville to Afton every 2 hours. Alternatively, you can take a bus from Knoxville to Afton via Fountain City Superstop, Walmart, Knoxville, New York City, New York, and Binghamton in around 19h 55m.

- Website
- delta.com
Flights from Knoxville to Binghamton via New York La Guardia
- Ave. Duration
- 5h 3m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
- Estimated price
- $150 - $310
Flights from Knoxville to Binghamton via Atlanta, New York La Guardia
- Ave. Duration
- 7h 17m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
- Estimated price
- $160 - $310
Flights from Knoxville to Binghamton via Detroit, New York La Guardia
- Ave. Duration
- 7h 38m
- When
- Monday, Thursday and Friday
- Estimated price
- $160 - $310

- Website
- aa.com
Flights from Knoxville to Scranton/Wilkes-Barre via Charlotte
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $100 - $420
Flights from Knoxville to Scranton/Wilkes-Barre via Chicago O'Hare
- Ave. Duration
- 4h 31m
- When
- Thursday and Friday
- Estimated price
- $110 - $420
Flights from Knoxville to Scranton/Wilkes-Barre via New York La Guardia, Charlotte
- Ave. Duration
- 8h 7m
- When
- Saturday
- Estimated price
- $130 - $430
Flights from Knoxville to Scranton/Wilkes-Barre via Charlotte, Chicago O'Hare
- Ave. Duration
- 8h 38m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
- Estimated price
- $120 - $430
Flights from Knoxville to Scranton/Wilkes-Barre via Philadelphia, Chicago O'Hare
- Ave. Duration
- 8h 37m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
- Estimated price
- $130 - $430

- Website
- united.com
Flights from Knoxville to Scranton/Wilkes-Barre via Chicago O'Hare
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $130 - $430
Flights from Knoxville to Scranton/Wilkes-Barre via Washington Dulles, Newark
- Ave. Duration
- 6h 23m
- When
- Monday, Tuesday, Wednesday, Thursday and Sunday
- Estimated price
- $120 - $410

Amtrak’s Northeast Regional train service serves the US’ busy northeast corridor from Virginia to Massachusetts; major stops include Boston, Providence, New York City, Philadelphia, Washington DC and Baltimore. Amenities include Wi-Fi, a quiet car, cafe and business-class seating, and travelling with a small dog or cat is permitted. Book at least 14 days in advance for a cheaper Saver Fare.
Rome2Rio's guide to Amtrak Northeast Regional
Contact Details
- Phone
- +1 800-523-6590
- Website
- amtrak.com
Train from Roanoke to New York Penn Station
- Ave. Duration
- 9h 27m
- Frequency
- Twice daily
- Estimated price
- $50 - $240
- Website
- http://www.amtrak.com
- Schedules at
- https://www.amtrak.com/northeast-regional-train
- Book at
- https://www.amtrak.com/home.html
- Child 2-12 with paid adult
- $23 - $120
- Reserved Coach Seat
- $50 - $240
- Business Class Seat
- $170 - $390

- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Night bus from Scranton to Binghamton
- Ave. Duration
- 1h
- Frequency
- 5 times a week
- Estimated price
- $7 - $40
- Schedules at
- flixbus.com
- Adult
- $7 - $40

- Phone
- +1 615-939-8887
- tennesseetravel@gotobus.com
- Website
- nytnbus.com
Bus from Knoxville to New York City
- Ave. Duration
- 12h
- Frequency
- Twice daily
- Estimated price
- $75 - $120
- Schedules at
- nytnbus.com
- Book at
- gotobus.com
Bus from Knoxville to Christiansburg, VA - 2370 Roanoke St
- Ave. Duration
- 4h 44m
- Frequency
- Once daily
- Estimated price
- $70 - $80
- Schedules at
- nytnbus.com
- Book at
- gotobus.com

- Phone
- +1 212 965 8880
- nycstarline@gmail.com
- Website
- starlinebus.com
Bus from New York to Binghamton
- Ave. Duration
- 3h
- Frequency
- Once daily
- Estimated price
- $30 - $100
- Website
- http://www.starlinebus.com/

- Phone
- 646-630-7186
- help@wandacoach.com
- Website
- wandacoach.com
Bus from Knoxville to New York, NY
- Ave. Duration
- 13h
- Frequency
- 3 times a week
- Estimated price
- $95 - $130
- Website
- https://www.wandacoach.com
- Book at
- http://www.gotobus.com/cgi-bin/ivyu.cgi?gid=657605&d=wanda-travel/

- Phone
- +1 540 982 2222
- info@valleymetro.com
- Website
- valleymetro.com
Bus from Exit 118 - Park and Ride to Roanoke Amtrak Station
- Ave. Duration
- 35 min
- Frequency
- Once daily
- Estimated price
- $1 - $4
- Website
- Valley Metro Roanoke

- Phone
- +1-844-800-6828
- pr@ourbus.com
- Website
- ourbus.com
Bus from New York, NY to Binghamton, NY
- Ave. Duration
- 2h 50m
- Frequency
- Once a week
- Estimated price
- $26 - $35
- Website
- https://www.ourbus.com/bookTicket
Want to know more about travelling around United States
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The best way to get from Knoxville to Knoxville Airport is to taxi which takes 18 min and costs $55 - $70.