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There are 6 ways to get from Kissimmee to Panama City by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  9 h 10 min

  1. Take the bus from Orlando, Fl to Tallahassee, Fl 1247 / ...
  2. Take the bus from Tallahassee, Fl to Panama City, Fl 1243 / ...

$54 - $133

5 alternative options

Train, bus  •  9 h 55 min

  1. Take the train from Kissimmee Amtrak to Jacksonville Amtrak
  2. Take the bus from Jacksonville, Fl to Tallahassee, Fl
  3. Take the bus from Tallahassee, Fl to Panama City, Fl

$93 - $199

Drive  •  6 h 18 min

  1. Drive from Kissimmee to Panama City 371.2 miles

$35 - $55

Fly to Panama City  •  5 h 51 min

  1. Fly from Orlando (MCO) to Panama City (ECP) MCO - ECP

$222 - $507

Fly to Valparaiso, drive  •  6 h 55 min

  1. Fly from Orlando (MCO) to Valparaiso (VPS) MCO - VPS
  2. Drive from Valparaiso to Panama City

$178 - $352

Fly to Pensacola, bus  •  7 h 27 min

  1. Fly from Orlando (MCO) to Pensacola (PNS) MCO - PNS
  2. Take the bus from Pensacola, Fl to Panama City, Fl

$185 - $382

Questions & Answers

The cheapest way to get from Kissimmee to Panama City is to drive which costs $35 - $55 and takes 6 h 18 min.

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The quickest way to get from Kissimmee to Panama City is to fly which costs $220 - $550 and takes 5 h 51 min.

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No, there is no direct bus from Kissimmee to Panama City. However, there are services departing from Kissimmee, Fl and arriving at Panama City, Fl via Orlando, Fl and Tallahassee, Fl. The journey, including transfers, takes approximately 9 h 10 min.

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The distance between Kissimmee and Panama City is 288 miles. The road distance is 371.2 miles.

Get driving directions

The best way to get from Kissimmee to Panama City without a car is to bus which takes 9 h 10 min and costs $50 - $140.

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It takes approximately 9 h 10 min to get from Kissimmee to Panama City, including transfers.

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Kissimmee to Panama City bus services, operated by Greyhound USA, depart from Orlando, Fl station.

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The best way to get from Kissimmee to Panama City is to bus which takes 9 h 10 min and costs $50 - $140. Alternatively, you can fly, which costs $220 - $550 and takes 5 h 51 min.

Mode details

There is no direct flight from Orlando Airport to Panama City Airport. The quickest flight takes 3 h 37 min and has one stopover.

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Kissimmee to Panama City bus services, operated by Greyhound USA, arrive at Panama City, Fl station.

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Map of how to get from Kissimmee to Panama City.
Launch map view
  • Distance: 287.8 miles
  • Duration: 9 h 10 min

What companies run services between Kissimmee, FL, USA and Panama City, FL, USA?

You can take a bus from Kissimmee to Panama City via Orlando, Fl and Tallahassee, Fl in around 9 h 10 min. Alternatively, Delta, American Airlines and two other airlines fly from Kissimmee to Panama City hourly.

Airlines
Delta
Website
delta.com
Flights from Orlando to Panama City via Atlanta
Ave. Duration
3 h 52 min
When
Every day
Estimated price
$270 - $650
Flights from Orlando to Valparaiso via Atlanta
Ave. Duration
4 h
When
Every day
Estimated price
$270 - $600
Flights from Orlando to Valparaiso via Raleigh/Durham, Atlanta
Ave. Duration
7 h 14 min
When
Monday to Friday
Estimated price
$270 - $600
Flights from Orlando to Pensacola via Atlanta
Ave. Duration
4 h 5 min
When
Every day
Estimated price
$240 - $600
American Airlines
Website
aa.com
Flights from Orlando to Panama City via Charlotte
Ave. Duration
5 h 2 min
When
Every day
Estimated price
$230 - $1,100
Flights from Orlando to Panama City via Dallas/Ft.Worth
Ave. Duration
6 h 13 min
When
Every day
Estimated price
$300 - $1,200
Flights from Orlando to Panama City via Chicago O'Hare
Ave. Duration
7 h 3 min
When
Saturday
Estimated price
$310 - $1,300
Flights from Orlando to Valparaiso via Charlotte
Ave. Duration
5 h 11 min
When
Every day
Estimated price
$280 - $600
Flights from Orlando to Valparaiso via Dallas/Ft.Worth
Ave. Duration
6 h 6 min
When
Every day
Estimated price
$280 - $600
Flights from Orlando to Pensacola via Miami
Ave. Duration
4 h 17 min
When
Every day
Estimated price
$240 - $600
Flights from Orlando to Pensacola via Charlotte
Ave. Duration
4 h 37 min
When
Every day
Estimated price
$240 - $600
Southwest Airlines
Website
southwest.com
Flights from Orlando to Panama City via Houston Hobby Apt
Ave. Duration
6 h 12 min
When
Every day
Estimated price
$290 - $950
Flights from Orlando to Panama City via Dallas
Ave. Duration
5 h 35 min
When
Saturday
Estimated price
$290 - $950
Flights from Orlando to Panama City via Nashville
Ave. Duration
6 h 50 min
When
Tuesday, Wednesday, Friday and Saturday
Estimated price
$290 - $950
Flights from Orlando to Panama City via St. Louis
Ave. Duration
6 h 45 min
When
Saturday
Estimated price
$290 - $950
Flights from Orlando to Panama City via Austin
Ave. Duration
7 h 35 min
When
Saturday
Estimated price
$290 - $950
United Airlines
Website
united.com
Flights from Orlando to Panama City via Houston
Ave. Duration
6 h 15 min
When
Every day
Estimated price
$280 - $1,300
Flights from Orlando to Valparaiso via Houston
Ave. Duration
6 h 36 min
When
Every day
Estimated price
$250 - $1,100
Flights from Orlando to Pensacola
Ave. Duration
2 h
When
Every day
Estimated price
$150 - $650
Silver Airways
Website
silverairways.com
Flights from Orlando to Pensacola
Ave. Duration
2 h
When
Every day
Estimated price
$150 - $650
Train operators
Amtrak

Amtrak is a rail service that connects the US and three Canadian provinces. Covering 21,000 route miles (34,000km) Amtrak operates more than 300 trains daily. These medium and long distance intercity services operate at speeds of up to 240km/h, to more than 500 destinations. Founded in 1971, it is based in Washington, D.C. and offers four classes of travel: First Class, Sleeper, Business and Coach. Ticket fares are divided into five subclasses: Saver, Value, Flexible, Business and Premium. Amtrak trains are known for their wide seats, plug-in power, big windows and storage capabilities.

Rome2rio's guide to Amtrak
Contact Details
Phone
+1 215-856-7924
Website
amtrak.com
Train from Kissimmee Amtrak to Jacksonville Amtrak
Ave. Duration
3 h 51 min
Frequency
Twice daily
Estimated price
$35 - $90
Website
amtrak.com
Coach Seat
$35 - $55
Flexi Coach Seat
$65 - $95
Business Coach Seat
$60 - $90
Room
$180 - $260
Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Orlando, Fl to Tallahassee, Fl
Ave. Duration
5 h 15 min
Frequency
Every 2 hours
Estimated price
$29 - $75
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $75
Bus from Tallahassee, Fl to Panama City, Fl
Ave. Duration
1 h 15 min
Frequency
Every 2 hours
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$28 - $40
Bus from Jacksonville, Fl to Tallahassee, Fl
Ave. Duration
2 h 40 min
Frequency
Twice daily
Estimated price
$21 - $50
Website
greyhound.com
Economy
$21 - $35
Flexible
$35 - $50
Bus from Pensacola, Fl to Panama City, Fl
Ave. Duration
2 h 40 min
Frequency
Every 4 hours
Estimated price
$17 - $40
Website
greyhound.com
Economy
$17 - $26
Flexible
$30 - $40

Want to know more about travelling around United States

Rome2rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

More Questions & Answers

Panama City is 1 h behind Kissimmee. It is currently 4:17 PM in Kissimmee and 3:17 PM in Panama City.

Yes, the driving distance between Kissimmee to Panama City is 371 miles. It takes approximately 6 h 18 min to drive from Kissimmee to Panama City.

Get driving directions

United Airlines, American Airlines, Delta and Southwest Airlines offer flights from Orlando Airport to Panama City Airport.

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Book your Kissimmee to Panama City bus tickets online with Greyhound and Greyhound.

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There are 1057+ hotels available in Panama City. Prices start at $69 USD per night.

More details

The best way to get from Kissimmee to Orlando Airport is to line 407 bus which takes 38 min and costs $3.

More details