There are 8 ways to get from Kissimmee to Panama City by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  7 h 37 min

  1. Take the bus from Orlando, Fl to Tallahassee, Fl 1243 / ...
  2. Take the bus from Tallahassee, Fl to Panama City, Fl 1243 / ...

$54 - $133

7 alternative options

Train, bus  •  8 h 34 min

  1. Take the train from Kissimmee Amtrak to Jacksonville Amtrak
  2. Take the bus from Jacksonville, Fl to Tallahassee, Fl
  3. Take the bus from Tallahassee, Fl to Panama City, Fl

$93 - $199

Drive  •  6 h 18 min

  1. Drive from Kissimmee to Panama City 371.2 miles

$35 - $55

Fly Orlando to Panama City  •  5 h 47 min

  1. Fly from Orlando (MCO) to Panama City (ECP) MCO - ECP

$222 - $507

Fly Orlando to Tallahassee, bus  •  4 h 38 min

  1. Fly from Orlando (MCO) to Tallahassee (TLH) MCO - TLH
  2. Take the bus from Tallahassee, Fl to Panama City, Fl

$148 - $442

Fly Orlando to Pensacola, bus  •  6 h 44 min

  1. Fly from Orlando (MCO) to Pensacola (PNS) MCO - PNS
  2. Take the bus from Pensacola, Fl to Panama City, Fl

$185 - $382

Fly Orlando to Valparaiso, drive  •  6 h 50 min

  1. Fly from Orlando (MCO) to Valparaiso (VPS) MCO - VPS
  2. Drive from Valparaiso to Panama City

$178 - $352

Train to Tampa, fly to Tallahassee, bus  •  6 h 54 min

  1. Take the train from Kissimmee Amtrak to Tampa Amtrak
  2. Fly from Tampa (TPA) to Tallahassee (TLH) TPA - TLH
  3. Take the bus from Tallahassee, Fl to Panama City, Fl

$179 - $561

What companies run services between Kissimmee, FL, USA and Panama City, FL, USA?

You can take a bus from Kissimmee to Panama City via Orlando, Fl and Tallahassee, Fl in around 7 h 37 min. Alternatively, Delta, Southwest Airlines and two other airlines fly from Kissimmee to Panama City hourly.

Airlines
Delta
Website
delta.com
Flights from Orlando to Panama City via Atlanta
Ave. Duration
4 h
When
Every day
Estimated price
$270 - $650
Flights from Orlando to Tallahassee via Atlanta
Ave. Duration
3 h 40 min
When
Every day
Estimated price
$400 - $1,300
Flights from Orlando to Pensacola via Atlanta
Ave. Duration
4 h 6 min
When
Every day
Estimated price
$240 - $600
Flights from Orlando to Valparaiso via Atlanta
Ave. Duration
4 h 10 min
When
Every day
Estimated price
$270 - $600
Southwest Airlines
Website
southwest.com
Flights from Orlando to Panama City via Nashville
Ave. Duration
4 h 45 min
When
Every day
Estimated price
$290 - $950
Flights from Orlando to Panama City via St. Louis
Ave. Duration
6 h 15 min
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$290 - $950
Flights from Orlando to Panama City via Dallas
Ave. Duration
6 h
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$290 - $950
Flights from Orlando to Panama City via Baltimore
Ave. Duration
6 h 6 min
When
Every day
Estimated price
$290 - $950
Flights from Orlando to Panama City via Houston Hobby Apt
Ave. Duration
6 h 22 min
When
Saturday and Sunday
Estimated price
$290 - $950
Flights from Orlando to Panama City via Chicago Midway
Ave. Duration
6 h 30 min
When
Saturday
Estimated price
$290 - $950
Flights from Orlando to Pensacola via Nashville
Ave. Duration
4 h 10 min
When
Sunday
Estimated price
$370 - $950
American Airlines
Website
aa.com
Flights from Orlando to Panama City via Charlotte
Ave. Duration
4 h 47 min
When
Every day
Estimated price
$230 - $1,100
Flights from Orlando to Panama City via Dallas/Ft.Worth
Ave. Duration
6 h 11 min
When
Every day
Estimated price
$300 - $1,200
Flights from Orlando to Pensacola via Miami
Ave. Duration
4 h 18 min
When
Every day
Estimated price
$240 - $600
Flights from Orlando to Pensacola via Charlotte
Ave. Duration
4 h 29 min
When
Every day
Estimated price
$240 - $600
Flights from Orlando to Valparaiso via Charlotte
Ave. Duration
4 h 56 min
When
Every day
Estimated price
$280 - $600
Flights from Orlando to Valparaiso via Dallas/Ft.Worth
Ave. Duration
6 h 9 min
When
Every day
Estimated price
$280 - $600
United Airlines
Website
united.com
Flights from Orlando to Panama City via Houston
Ave. Duration
5 h 38 min
When
Every day
Estimated price
$280 - $1,300
Flights from Orlando to Tallahassee
Ave. Duration
1 h 23 min
When
Monday to Friday
Estimated price
$110 - $900
Flights from Orlando to Pensacola
Ave. Duration
2 h 5 min
When
Every day
Estimated price
$150 - $650
Flights from Orlando to Valparaiso via Houston
Ave. Duration
5 h 40 min
When
Every day
Estimated price
$250 - $1,100
Flights from Tampa to Tallahassee
Ave. Duration
1 h 12 min
When
Every day
Estimated price
$100 - $460
Silver Airways
Website
silverairways.com
Flights from Orlando to Tallahassee
Ave. Duration
1 h 23 min
When
Monday to Friday
Estimated price
$110 - $900
Flights from Orlando to Pensacola
Ave. Duration
2 h 5 min
When
Every day
Estimated price
$150 - $650
Flights from Tampa to Tallahassee
Ave. Duration
1 h 12 min
When
Every day
Estimated price
$100 - $460
Train operators
Amtrak
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Kissimmee Amtrak to Jacksonville Amtrak
Ave. Duration
3 h 51 min
Frequency
Twice daily
Estimated price
$35 - $90
Website
amtrak.com
Coach Seat
$35 - $55
Flexi Coach Seat
$65 - $95
Business Coach Seat
$60 - $90
Room
$180 - $260
Train from Kissimmee Amtrak to Tampa Amtrak
Ave. Duration
1 h 39 min
Frequency
Once daily
Estimated price
$27 - $55
Website
amtrak.com
Coach Seat
$27 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$150 - $210
Bus operators
Greyhound USA
Phone
+1 214-849-8100
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Orlando, Fl to Tallahassee, Fl
Ave. Duration
5 h 15 min
Frequency
Hourly
Estimated price
$29 - $75
Website
greyhound.com
Economy
$29 - $50
Flexible
$55 - $75
Bus from Tallahassee, Fl to Panama City, Fl
Ave. Duration
1 h 15 min
Frequency
Every 15 minutes
Estimated price
$16 - $40
Website
greyhound.com
Economy
$16 - $24
Flexible
$28 - $40
Bus from Jacksonville, Fl to Tallahassee, Fl
Ave. Duration
2 h 40 min
Frequency
Hourly
Estimated price
$21 - $50
Website
greyhound.com
Economy
$21 - $35
Flexible
$35 - $50
Bus from Pensacola, Fl to Panama City, Fl
Ave. Duration
2 h 40 min
Frequency
Every 30 minutes
Estimated price
$17 - $40
Website
greyhound.com
Economy
$17 - $26
Flexible
$30 - $40

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Questions & Answers

How far is it from Kissimmee to Panama City?

The distance between Kissimmee and Panama City is 460 km. The road distance is 594 km.

What is the cheapest way to get from Kissimmee to Panama City?

The cheapest way to get from Kissimmee to Panama City is to drive which costs $35 - $55 and takes 6 h 18 min.

What is the fastest way to get from Kissimmee to Panama City?

The quickest way to get from Kissimmee to Panama City is to fly and bus which takes 4 h 38 min and costs $140 - $450.

Is there a direct bus between Kissimmee and Panama City?

No, there is no direct bus from Kissimmee to Panama City. However, there are services departing from Kissimmee, Fl and arriving at Panama City, Fl via Orlando, Fl and Tallahassee, Fl. The journey, including transfers, takes approximately 7 h 37 min.

How long does it take to get from Kissimmee to Panama City?

It takes approximately 7 h 37 min to get from Kissimmee to Panama City, including transfers.