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How to get fromKissimmee to Key Largoby bus (Greyhound), train, bus, car, plane, bus (Flixbus, Greyhound), or shuttle

Find Transport to Key Largo

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There are 10 ways to get from Kissimmee to Key Largo by bus (Greyhound), train, bus, car, plane, bus (Flixbus, Greyhound), or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus via Pembroke Pines

    best
    1. Take the bus from Kissimmee -1471 East Osceola Parkway to Sheridan Tri-Rail Stationbus bus Orlando to Miami
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus Greyhound US0720s
    8h 6m
    $43–70

  2. Train, bus via Delray Beach

    1. Take the train from Kissimmee Amtrak Station to Delray Beach Amtraktrain train
    2. Take the train from Delray Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    8h 8m
    $77–158

  3. Drive 259.1 mi

    1. Drive from Kissimmee to Key Largocar car 259.1 mi
    5h 12m
    $48–69

  4. Fly Orlando to Miami International Airport, bus

    1. Fly from Orlando (MCO) to Miami International Airport (MIA)plane plane MCO - MIA
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    5h 21m
    $562–1,122

  5. Bus

    1. Take the bus from Orlando to Miami Airport Stationbus bus FlixBus 2411 / ...
    2. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus Greyhound US0720s
    8h 19m
    $45–79

  6. Bus, train

    1. Take the bus from Kissimmee -1471 East Osceola Parkway to West Palm Beach, FLbus bus
    2. Take the train from West Palm Beach Station to Miami Airport Stationtrain train
    3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    8h 37m
    $50–105

  7. Train, bus

    1. Take the train from Kissimmee Amtrak Station to Miami Amtrak Stationtrain train Silver Meteor / ...
    2. Take the bus from W Palm Dr @ 3 Ave to Mile Marker 98 Key Largobus bus 301
    9h 5m
    $88–171

  8. Fly Orlando to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Fly from Orlando (MCO) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane MCO - FLL
    2. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    5h 38m
    $374–755

  9. Train to Tampa, fly to Miami International Airport, bus

    1. Take the train from Kissimmee Amtrak Station to Tampatrain train
    2. Fly from Tampa (TPA) to Miami International Airport (MIA)plane plane TPA - MIA
    3. Take the bus from Miami Airport Station to Key Largo Bus Stopbus bus
    7h 35m
    $788–1,173

  10. Train to Tampa, fly to Fort Lauderdale–Hollywood International Airport, shuttle

    1. Take the train from Kissimmee Amtrak Station to Tampatrain train
    2. Fly from Tampa (TPA) to Fort Lauderdale–Hollywood International Airport (FLL)plane plane TPA - FLL
    3. Take a shuttle bus from Fort Lauderdale, FL - International Airport to Key Largo, FLshuttle bus
    7h 49m
    $260–756

Kissimmee to Key Largo by bus and train

Calendar14Weekly Services
Duration8h 6mAverage Duration
Ticket$43Cheapest Price
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Comparing Your Travel Options

Map of how to get from Kissimmee to Key Largo.ExpandLaunch map view
  • Distance: 282.8 mi
  • Duration: 8h 6m

What companies run services between Kissimmee, FL, USA and Key Largo, FL, USA?

You can take a bus from E Vine St & Brack St to Key Largo Bus Stop via Osceola Pkwy Walmart, Kissimmee -1471 East Osceola Parkway, Sheridan Tri-Rail Station, Sheridan Street Station, Miami, Airport Intermodal Station, and Miami Airport Station in around 8h 6m.

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