There are 5 ways to get from Kissimmee to Florida Keys by bus, train, car or plane

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Bus  •  10 h 59 min

  1. Take the bus from Kissimmee, Fl to Ft Pierce, Fl
  2. Take the bus from Ft Pierce, Fl to Miami, Fl
  3. Take the bus from Miami, Fl to Big Pine Key

$56 - $129

4 alternative options

Train, bus  •  11 h 28 min

  1. Take the train from Kissimmee Amtrak to Hollywood Amtrak Silver Meteor / ...
  2. Take the bus from Miami, Fl to Big Pine Key 3715 / ...

$69 - $165

Drive  •  6 h 39 min

  1. Drive from Kissimmee to Florida Keys 362.5 miles

$35 - $55

Fly from Orlando  •  4 h 58 min

  1. Fly from Orlando (MCO) to Key West (EYW) MCO - EYW

$114 - $436

Train to Tampa, fly  •  7 h 7 min

  1. Take the train from Kissimmee Amtrak to Tampa Amtrak
  2. Fly from Tampa (TPA) to Key West (EYW) TPA - EYW

$133 - $494

Questions & Answers

The cheapest way to get from Kissimmee to Florida Keys is to drive which costs $35 - $55 and takes 6 h 39 min.

More details

The quickest way to get from Kissimmee to Florida Keys is to fly which costs $110 - $440 and takes 4 h 58 min.

More details

The distance between Kissimmee and Florida Keys is 254 miles. The road distance is 362.5 miles.

Get driving directions

It takes approximately 10 h 59 min to get from Kissimmee to Florida Keys, including transfers.

More details

No, there is no direct bus from Kissimmee to Florida Keys. However, there are services departing from Kissimmee, Fl and arriving at Sugarloaf Key, FL via Ft Pierce, Fl, Miami, Fl and Lower Keys Shuttle. The journey, including transfers, takes approximately 10 h 59 min.

More details

What companies run services between Kissimmee, FL, USA and Florida Keys, FL, USA?

You can take a bus from Kissimmee to Florida Keys via Ft Pierce, Fl, Miami, Fl, Big Pine Key, Lower Keys Shuttle, and Sugarloaf Key, FL in around 10 h 59 min. Alternatively, Silver Airways and American Airlines fly from Kissimmee to Florida Keys every 4 hours.

Airlines
Silver Airways
Website
silverairways.com
Flights from Orlando to Key West
Ave. Duration
1 h 30 min
When
Every day
Estimated price
$160 - $800
Flights from Orlando to Key West via Fort Lauderdale
Ave. Duration
4 h
When
Monday, Tuesday, Wednesday, Thursday, Friday and Sunday
Estimated price
$160 - $800
Flights from Tampa to Key West
Ave. Duration
1 h 19 min
When
Every day
Estimated price
$200 - $850
American Airlines
Website
aa.com
Flights from Orlando to Key West via Miami
Ave. Duration
3 h 19 min
When
Every day
Estimated price
$180 - $650
Flights from Tampa to Key West via Miami
Ave. Duration
3 h 11 min
When
Every day
Estimated price
$250 - $1,100
Train operators
Amtrak
Rome2rio's guide to Amtrak
Contact Details
Phone
+1 1-800-872-7245
Website
amtrak.com
Train from Kissimmee Amtrak to Hollywood Amtrak
Ave. Duration
4 h 33 min
Frequency
Twice daily
Estimated price
$45 - $120
Website
amtrak.com
Coach Seat
$45 - $70
Flexi Coach Seat
$80 - $120
Business Coach Seat
$80 - $120
Room
$210 - $300
Train from Kissimmee Amtrak to Tampa Amtrak
Ave. Duration
1 h 39 min
Frequency
Once daily
Estimated price
$27 - $55
Website
amtrak.com
Coach Seat
$27 - $40
Flexi Coach Seat
$45 - $70
Business Coach Seat
$35 - $55
Room
$150 - $210
Bus operators
Greyhound USA
Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Kissimmee, Fl to Ft Pierce, Fl
Ave. Duration
1 h 40 min
Frequency
Hourly
Estimated price
$15 - $40
Website
greyhound.com
Economy
$15 - $23
Flexible
$28 - $40
Bus from Ft Pierce, Fl to Miami, Fl
Ave. Duration
3 h
Frequency
Hourly
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $29
Flexible
$30 - $45
Bus from Miami, Fl to Big Pine Key
Ave. Duration
3 h 35 min
Frequency
Hourly
Estimated price
$19 - $45
Website
greyhound.com
Economy
$19 - $29
Flexible
$30 - $45

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