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There are 3 ways to get from Key West to Sanibel Island by ferry, bus or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2rio's travel planner.

Recommended option

Ferry  •  3h 46m

  1. Take the ferry from Key West, FL to Fort Myers Beach, FL Key West

$125 - $135

Cheapest option

Bus  •  12h 9m

  1. Take the bus from Key West, Fl to Miami, Fl 3718 / ...
  2. Take the bus from Miami, Fl to Ft Myers, Fl 1008 / ...

$48 - $77

1 alternative option

Drive  •  5h 50m

  1. Drive from Key West to Cape Coral 299.9 miles

$29 - $45

Questions & Answers

The cheapest way to get from Key West to Sanibel Island is to drive which costs $29 - $45 and takes 5h 50m.

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The quickest way to get from Key West to Sanibel Island is to ferry which costs $120 - $140 and takes 3h 46m.

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No, there is no direct bus from Key West to Sanibel Island. However, there are services departing from Flagler & Josephine and arriving at Forty-Seventh Terrace @ Vincennes Boulevard via Key West, Fl, Miami, Fl and Rosa Parks Transportation Center. The journey, including transfers, takes approximately 12h 9m.

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The distance between Key West and Sanibel Island is 133 miles. The road distance is 299.9 miles.

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The best way to get from Key West to Sanibel Island without a car is to ferry which takes 3h 46m and costs $120 - $140.

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It takes approximately 3h 46m to get from Key West to Sanibel Island, including transfers.

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Key West to Sanibel Island bus services, operated by Greyhound USA, depart from Key West, Fl station.

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Key West to Sanibel Island bus services, operated by Greyhound USA, arrive at Ft Myers, Fl station.

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Yes, the driving distance between Key West to Sanibel Island is 300 miles. It takes approximately 5h 50m to drive from Key West to Sanibel Island.

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There are 1396+ hotels available in Sanibel Island. Prices start at $119 USD per night.

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Map of how to get from Key West to Sanibel Island.
Launch map view
  • Distance: 132.7 miles
  • Duration: 3h 46m

What companies run services between Key West, FL, USA and Sanibel Island, FL, USA?

You can take a bus from Key West to Cape Coral via Key West, Fl, Miami, Fl, Ft Myers, Fl, and Rosa Parks Transportation Center in around 12h 9m.

Bus operators
Greyhound USA

Greyhound is a leading bus company based in Dallas, Texas, serving over 3800 destinations across North America, Mexico and Canada. Greyhound carries around 18 million passengers a year who travel 5.4 billion miles (8.6 billion km) a year on their fleet of around 1700 vehicles. For travel flexibility, you can board or get off a Greyhound bus at official Greyhound stations, partner stations and curbside stops. There are around 230 Greyhound stations across the US where you can both catch your bus and buy tickets, that are also available on the official website and via the mobile app.

Rome2rio's guide to Greyhound USA
Contact Details
Phone
+1 214-849-8100/1-800-231-2222
Email
ifsr@greyhound.com
Website
greyhound.com
Bus from Key West, Fl to Miami, Fl
Ave. Duration
4h 15m
Frequency
Twice daily
Estimated price
$22 - $35
Website
greyhound.com
Economy
$22 - $35
Flexible
$40 - $65
Bus from Miami, Fl to Ft Myers, Fl
Ave. Duration
4h 10m
Frequency
Every 4 hours
Estimated price
$23 - $35
Website
greyhound.com
Economy
$23 - $35
Flexible
$45 - $65
Ferry operators
Key West Express
Phone
+1 239-463-5733
Website
keywestexpress.net
Ferry from Key West, FL to Fort Myers Beach, FL
Ave. Duration
3h 30m
Frequency
Once daily
Estimated price
$95
Book at
Key West Express

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