There are 4 ways to get from Key West to Myrtle Beach by plane, shuttle, train, bus, bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Key West International Airport (EYW) to Myrtle Beach (MYR)plane EYW - MYR
4h 43m$112–507Shuttle, train, bus
- Take a shuttle bus from Key West, FL to Miami, FL - International Airport
- Take the train from Miami Amtrak Station to Charleston Amtrak Stationtrain
- Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus
23h 46m$270–413Bus
- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Atlanta Bus Stationbus
- Take the bus from Atlanta Bus Station to Myrtle Beach Bus Stationbus
29h 27m$132–309Drive 833.8 mi
- Drive from Key West to Myrtle Beachcar 833.8 mi
15h 19m$153–220
Key West International Airport (EYW) to Myrtle Beach (MYR) flights
Questions & Answers
The cheapest way to get from Key West to Myrtle Beach is to drive which costs $150 - $220 and takes 15h 19m.
The fastest way to get from Key West to Myrtle Beach is to fly which takes 4h 43m and costs $110 - $550.
No, there is no direct bus from Key West to Myrtle Beach station. However, there are services departing from N Roosevelt & 3rd Street and arriving at Myrtle Beach Bus Station via Big Pine Key, Miami Airport Station and Atlanta Bus Station. The journey, including transfers, takes approximately 29h 27m.
The distance between Key West and Myrtle Beach is 662 miles. The road distance is 838.7 miles.
The best way to get from Key West to Myrtle Beach without a car is to shuttle and train and bus which takes 23h 46m and costs $270 - $420.
It takes approximately 4h 43m to get from Key West to Myrtle Beach, including transfers.
Key West to Myrtle Beach bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.
The best way to get from Key West to Myrtle Beach is to fly which takes 4h 43m and costs $110 - $550. Alternatively, you can bus, which costs $130 - $310 and takes 29h 27m.
Key West to Myrtle Beach bus services, operated by Key West Transit, arrive at Big Pine Key - Auto Store / NAPA MM30 station.
Yes, the driving distance between Key West to Myrtle Beach is 839 miles. It takes approximately 15h 19m to drive from Key West to Myrtle Beach.
What companies run services between Key West, FL, USA and Myrtle Beach, SC, USA?
American Airlines and Delta fly from Key West International Airport (EYW) to Myrtle Beach (MYR) 3 times a day. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Myrtle Beach Bus Station via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, and Atlanta Bus Station in around 29h 27m.
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Miami Amtrak Station to Charleston Amtrak Station
- Ave. Duration
- 13h 15m
- Frequency
- Once daily
- Estimated price
- $85–190
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Key West, FL to Miami, FL - International Airport
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Charleston Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $12–14
- Website
- https://www.greyhound.com/
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Atlanta Bus Station
- Ave. Duration
- 16h
- Frequency
- Once daily
- Estimated price
- $65–150
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 8h 40m
- Frequency
- Once daily
- Estimated price
- $50–70
- Website
- https://www.greyhound.com/
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Miami Airport Station to Atlanta Bus Station
- Ave. Duration
- 13h 10m
- Frequency
- Once daily
- Estimated price
- $50–170
- Schedules at
- flixbus.com
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