There are 4 ways to get from Key West to Myrtle Beach by plane, bus, train, bus (Greyhound, Flixbus), or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Key West International Airport (EYW) to Myrtle Beach (MYR)EYW - MYR
4h 51m$102–477Bus, train
- Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30Lks
- Take the bus from Big Pine Key to Miami Airport Station
- Take the train from Hollywood Amtrak Station to Charleston Amtrak Station
- Take the bus from Charleston Bus Station to Myrtle Beach Bus Station
23h 55m$131–380Bus
- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30Lks
- Take the bus from Big Pine Key to Miami Airport Station
- Take the bus from Miami Airport Station to Jacksonville
- Take the bus from Jacksonville to Florence Bus Station
- Take the bus from Florence to Myrtle Beach, SC
24h 21m$136–339Drive 833.8 mi
- Drive from Key West to Myrtle Beach833.8 mi
15h 11m$153–220
Key West to Myrtle Beach by bus, foot, and train
Questions & Answers
The cheapest way to get from Key West to Myrtle Beach is to drive which costs $150 - $220 and takes 15h 11m.
The fastest way to get from Key West to Myrtle Beach is to fly which takes 4h 51m and costs $100 - $480.
No, there is no direct bus from Key West to Myrtle Beach. However, there are services departing from N Roosevelt & 3rd Street and arriving at Myrtle Beach, SC via Big Pine Key, Miami Airport Station, Jacksonville and Florence. The journey, including transfers, takes approximately 24h 21m.
The distance between Key West and Myrtle Beach is 662 miles. The road distance is 838.7 miles.
The best way to get from Key West to Myrtle Beach without a car is to bus and train which takes 23h 55m and costs $130 - $380.
It takes approximately 4h 51m to get from Key West to Myrtle Beach, including transfers.
Key West to Myrtle Beach bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.
The best way to get from Key West to Myrtle Beach is to fly which takes 4h 51m and costs $100 - $480. Alternatively, you can bus, which costs $130 - $340 and takes 24h 21m.
Key West to Myrtle Beach bus services, operated by Key West Transit, arrive at Big Pine Key - Auto Store / NAPA MM30 station.
Yes, the driving distance between Key West to Myrtle Beach is 839 miles. It takes approximately 15h 11m to drive from Key West to Myrtle Beach.
What companies run services between Key West, FL, USA and Myrtle Beach, SC, USA?
Delta, American Airlines, and Spirit Airlines fly from Key West International Airport (EYW) to Myrtle Beach (MYR) 5 times a day. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Myrtle Beach, SC via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Jacksonville, Florence Bus Station, and Florence in around 24h 21m.
- Website
- delta.com
Flights from Key West International Airport to Myrtle Beach via Atlanta
- Ave. Duration
- 5h 7m
- When
- Every day
- Estimated price
- $90–470
- Website
- aa.com
Flights from Key West International Airport to Myrtle Beach via Charlotte
- Ave. Duration
- 5h 32m
- When
- Every day
- Estimated price
- $85–460
- Website
- spirit.com
Flights from Key West International Airport to Myrtle Beach via Fort Lauderdale
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $80–450
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Hollywood Amtrak Station to Charleston Amtrak Station
- Ave. Duration
- 12h 51m
- Frequency
- Once daily
- Estimated price
- $85–290
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 53 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $30–65
- Website
- https://www.greyhound.com/
Bus from Charleston Bus Station to Myrtle Beach Bus Station
- Ave. Duration
- 2h 25m
- Frequency
- Once daily
- Estimated price
- $11–15
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Jacksonville
- Ave. Duration
- 9h 45m
- Frequency
- Once daily
- Estimated price
- $40–95
- Website
- https://www.greyhound.com/
Bus from Florence to Myrtle Beach, SC
- Ave. Duration
- 1h 40m
- Frequency
- Once daily
- Estimated price
- $14–19
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Miami Airport Station to Jacksonville
- Ave. Duration
- 9h 10m
- Frequency
- Twice daily
- Estimated price
- $45–100
- Schedules at
- flixbus.com
Bus from Jacksonville to Florence Bus Station
- Ave. Duration
- 5h 10m
- Frequency
- Once daily
- Estimated price
- $50–75
- Schedules at
- flixbus.com
- Phone
- +1 404-591-2750
- info@southeasternstages.com
- Website
- southeasternstages.com
Bus from Florence to Myrtle Beach, SC
- Ave. Duration
- 1h 25m
- Frequency
- Once daily
- Estimated price
- $25–95
- Schedules at
- southeasternstages.com
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