Rome2Rio

How to get fromKey West to Missouriby plane, bus (Greyhound, Flixbus), shuttle, train or car

Find Transport to Missouri

See all options

There are 8 ways to get from Key West to Missouri by plane, bus (Greyhound, Flixbus), shuttle, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Springfield-Branson National Airport

    best
    1. Fly from Key West International Airport (EYW) to Springfield-Branson National Airport (SGF)plane plane EYW - SGF
    6h
    $148–634

  2. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to St Louis Bus Stationbus bus
    5. Take the bus from St Louis Bus Station to Kansas City Bus Stationbus bus
    36h 57m
    $219–494

  3. Shuttle, train

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus
    2. Take the train from Miami Amtrak Station to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Kansas Citytrain train
    2d 13h
    $867–1,804

  4. Drive 1,553.2 mi

    1. Drive from Key West to Kansas Citycar car 1,553.2 mi
    28h 48m
    $284–410

  5. Fly to Lambert–St. Louis International Airport

    1. Fly from Key West International Airport (EYW) to Lambert–St. Louis International Airport (STL)plane plane EYW - STL
    5h 37m
    $245–1,217

  6. Fly to Columbia Regional Airport

    1. Fly from Key West International Airport (EYW) to Columbia Regional Airport (COU)plane plane EYW - COU
    7h 31m
    $192–729

  7. Fly to Kansas City

    1. Fly from Key West International Airport (EYW) to Kansas City (MCI)plane plane EYW - MCI
    8h 1m
    $252–494

  8. Fly to Midamerica St. Louis Airport

    1. Fly from Key West International Airport (EYW) to Midamerica St. Louis Airport (BLV)plane plane EYW - BLV
    12h 16m
    $148–646

Key West to Missouri by bus and foot

Calendar7Weekly Services
Duration36h 57mAverage Duration
Ticket$219Cheapest Price
See schedules

Questions & Answers

What companies run services between Key West, FL, USA and Missouri, USA?

American Airlines, United Airlines, and Delta fly from Key West International Airport (EYW) to Springfield-Branson National Airport (SGF) every 4 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Kansas City Bus Station via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Atlanta Bus Station, and St Louis Bus Station in around 36h 57m.

Airlines
Train operators
Bus operators

Want to know more about travelling around United States

Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.

Related travel guides

Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

More Questions & Answers

Trips from Key West

Trips to Missouri

Popular routes