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How to get fromKey West to Mississippiby plane, bus (Greyhound, Flixbus), car, shuttle or bus

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There are 6 ways to get from Key West to Mississippi by plane, bus (Greyhound, Flixbus), car, shuttle, or bus

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Gulfport-Biloxi Regional Airport

    best
    1. Fly from Key West International Airport (EYW) to Gulfport-Biloxi Regional Airport (GPT)plane plane EYW - GPT
    5h 8m
    $163–778

  2. Bus

    cheapest
    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Jacksonbus bus
    28h 27m
    $132–324

  3. Drive 1,043.8 mi

    1. Drive from Key West to Jacksoncar car 1,043.8 mi
    18h 51m
    $191–276

  4. Fly to Memphis

    1. Fly from Key West International Airport (EYW) to Memphis (MEM)plane plane EYW - MEM
    4h 54m
    $193–890

  5. Fly to Jackson/Vicksburg

    1. Fly from Key West International Airport (EYW) to Jackson/Vicksburg (JAN)plane plane EYW - JAN
    4h 50m
    $147–564

  6. Shuttle, bus

    1. Take a shuttle bus from Plaza Hotel to Bayside Marketplaceshuttle bus
    2. Take the bus from Dolphin Mall - Miami to Lafayettebus bus
    3. Take the bus from Lafayette to Baton Rouge Bus Stationbus bus
    4. Take the bus from Baton Rouge Bus Station to Jacksonbus bus
    38h 11m
    $282–486

Key West to Mississippi by bus and foot

Calendar14Weekly Services
Duration28h 27mAverage Duration
Ticket$132Cheapest Price
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Questions & Answers

What companies run services between Key West, FL, USA and Mississippi, USA?

Delta, American Airlines, and Breeze Airways fly from Key West International Airport (EYW) to Gulfport-Biloxi Regional Airport (GPT) every 4 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Jackson via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, and Atlanta Bus Station in around 28h 27m.

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