There are 5 ways to get from Key West to Largo by plane, ferry, bus, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Saint Petersburg–Clearwater International Airport
best- Fly from Key West International Airport (EYW) to Saint Petersburg–Clearwater International Airport (PIE)plane EYW - PIE
1h 56m$65–387Ferry, bus via Marco Island
- Take the ferry from Key West, FL to Marco Island, FLferry Key West
- Take the bus from Naples, FL to St Petersburg 7-11bus Miami-Tampa
9h 48m$186–316Drive 398.7 mi
- Drive from Key West to Largocar 398.7 mi
7h 56m$73–106Fly to Tampa, line 300 bus
- Fly from Key West International Airport (EYW) to Tampa (TPA)plane EYW - TPA
- Take the bus from TPA RENTAL CAR FACILITY westbound to Ulmerton Park N Ride Lotbus
3h 21m$90–347Ferry, bus
- Take the ferry from Key West, FL to Fort Myers Beach, FLferry Key West
- Take the bus from Fort Myers Bus Stop to Tampa Bus Stationbus FlixBus 2421
12h 46m$150–167
Key West International Airport (EYW) to Saint Petersburg–Clearwater International Airport (PIE) flights
Questions & Answers
The cheapest way to get from Key West to Largo is to drive which costs $70 - $110 and takes 7h 56m.
The fastest way to get from Key West to Largo is to fly which takes 1h 56m and costs $60 - $390.
The distance between Key West and Largo is 249 miles. The road distance is 401.1 miles.
The best way to get from Key West to Largo without a car is to ferry and bus via Marco Island which takes 9h 48m and costs $180 - $320.
It takes approximately 1h 56m to get from Key West to Largo, including transfers.
Yes, the driving distance between Key West to Largo is 401 miles. It takes approximately 7h 56m to drive from Key West to Largo.
There are 3331+ hotels available in Largo.
What companies run services between Key West, FL, USA and Largo, FL, USA?
Allegiant Air flies from Key West International Airport (EYW) to Saint Petersburg–Clearwater International Airport (PIE) 6 times a week.
- Website
- allegiantair.com
Flights from Key West International Airport to Saint Petersburg–Clearwater International Airport
- Ave. Duration
- 1h 3m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $50–370
- Website
- flybreeze.com
Flights from Key West International Airport to Tampa
- Ave. Duration
- 1h 18m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $60–180
- Website
- aa.com
Flights from Key West International Airport to Tampa via Miami
- Ave. Duration
- 3h 15m
- When
- Every day
- Estimated price
- $55–370
- Website
- spirit.com
Flights from Key West International Airport to Tampa via Fort Lauderdale
- Ave. Duration
- 3h 8m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $85–380
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Naples, FL to St Petersburg 7-11
- Ave. Duration
- 2h 30m
- Frequency
- 5 times a week
- Estimated price
- $23–140
- Website
- https://www.redcoachusa.com
- Web
- $23–140
- Phone
- +1 727-540-1900
- ride@psta.net
- Website
- psta.net
Bus from TPA RENTAL CAR FACILITY westbound to Ulmerton Park N Ride Lot
- Ave. Duration
- 45 min
- Frequency
- Every 4 hours
- Estimated price
- $3
- Schedules at
- psta.net
- Adult
- $3
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Fort Myers Bus Stop to Tampa Bus Station
- Ave. Duration
- 2h 40m
- Frequency
- 4 times a day
- Estimated price
- $14–25
- Schedules at
- flixbus.com
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Key West, FL to Marco Island, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
Ferry from Key West, FL to Fort Myers Beach, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
Want to know more about travelling around United States
Rome2Rio's Travel Guide series provide vital information for the global traveller. Filled with useful and timely travel information, the guides answer all the hard questions - such as 'How do I buy a ticket?', 'Should I book online before I travel? ', 'How much should I expect to pay?', 'Do the trains and buses have Wifi?' - to help you get the most out of your next trip.
Related travel guides
Travelling to the US: What do I need to know?
Read the travel guide









