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How to get fromKey West to Indianapolisby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 5 ways to get from Key West to Indianapolis by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Key West International Airport (EYW) to Indianapolis (IND)plane plane EYW - IND
    3h 54m
    $154–666

  2. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Indianapolisbus bus
    34h 32m
    $181–364

  3. Bus, train

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Amtrak Station to Alexandriatrain train
    4. Take the train from Alexandria to Indianapolistrain train
    2d
    $609–1,267

  4. Drive 1,289 mi

    1. Drive from Key West to Indianapoliscar car 1,289 mi
    23h 59m
    $236–340

  5. Bus via Indianapolis, Illinois St (Greyhound Bus Station)

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Indianapolis Union Stationbus bus
    35h 22m
    $191–394

Key West to Indianapolis by bus and foot

Calendar12Weekly Services
Duration34h 32mAverage Duration
Ticket$181Cheapest Price
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Questions & Answers

Map of how to get from Key West to Indianapolis.ExpandLaunch map view
  • Distance: 1,097.3 mi
  • Duration: 3h 54m

What companies run services between Key West, FL, USA and Indianapolis, IN, USA?

Allegiant Air, Delta, and American Airlines fly from Key West International Airport (EYW) to Indianapolis (IND) every 4 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Indianapolis via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, and Atlanta Bus Station in around 34h 32m.

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