There are 9 ways to get from Key West to Gainesville by plane, shuttle, bus, car, bus (Greyhound, Flixbus), train, or ferry
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Gainesville Regional Airport
best- Fly from Key West International Airport (EYW) to Gainesville Regional Airport (GNV)plane EYW - GNV
5h 29m$79–416Bus, train
cheapest- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the train from Miami Airport Station to West Palm Beach Stationtrain
- Take the bus from West Palm Beach, FL to Gainesville - Commuter Lot Parking Garage @ Gale Lemerandbus
13h 50m$54–184Shuttle, bus
- Take a shuttle bus from Key West, FL to Miami, FL - International AirportTo the Airports
- Take the bus from Miami Airport to Gainesville - Commuter Lot Parking Garage @ Gale Lemerandbus Miami-Tallahassee / ...
12h 42m$198–344Drive 474.7 mi
- Drive from Key West to Gainesvillecar 474.7 mi
9h 22m$87–126Fly to Orlando, bus
- Fly from Key West International Airport (EYW) to Orlando (MCO)plane EYW - MCO
- Take the bus from Orlando RedCoach Station to Gainesvillebus
4h 45m$96–456Fly to Jacksonville, bus
- Fly from Key West International Airport (EYW) to Jacksonville (JAX)plane EYW - JAX
- Take the bus from Jacksonville to Gainesvillebus
7h 25m$259–689Bus
- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Gainesvillebus
13h 27m$69–103Bus, train via Meadow Woods
- Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the train from Miami to Orlandotrain
- Take the bus from Orlando RedCoach Station to Gainesvillebus
13h 41m$81–427Ferry, bus
- Take the ferry from Key West, FL to Fort Myers Beach, FLferry
- Take the bus from Fort Myers Bus Stop to University of South Floridabus
- Take the bus from University of South Florida Tampa to Gainesville - Commuter Lot Parking Garage @ Gale Lemerandbus
15h 10m$181–314
Key West International Airport (EYW) to Gainesville Regional Airport (GNV) flights
Questions & Answers
The cheapest way to get from Key West to Gainesville is to bus which costs $65 - $110 and takes 13h 27m.
The fastest way to get from Key West to Gainesville is to fly and bus which takes 4h 45m and costs $95 - $460.
No, there is no direct bus from Key West to Gainesville. However, there are services departing from N Roosevelt & 3rd Street and arriving at Gainesville via Big Pine Key and Miami Airport Station. The journey, including transfers, takes approximately 13h 27m.
The distance between Key West and Gainesville is 368 miles. The road distance is 477.4 miles.
The best way to get from Key West to Gainesville without a car is to shuttle and bus which takes 12h 42m and costs $190 - $350.
It takes approximately 5h 29m to get from Key West to Gainesville, including transfers.
Key West to Gainesville bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.
The best way to get from Key West to Gainesville is to fly which takes 5h 29m and costs $75 - $420. Alternatively, you can bus, which costs $65 - $110 and takes 13h 27m.
Key West to Gainesville bus services, operated by Key West Transit, arrive at Big Pine Key - Auto Store / NAPA MM30 station.
Yes, the driving distance between Key West to Gainesville is 477 miles. It takes approximately 9h 22m to drive from Key West to Gainesville.
What companies run services between Key West, FL, USA and Gainesville, FL, USA?
Delta and American Airlines fly from Key West International Airport (EYW) to Gainesville Regional Airport (GNV) every 4 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Gainesville via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, and Miami Airport Station in around 13h 27m.
- Website
- aa.com
Flights from Key West International Airport to Gainesville Regional Airport via Miami
- Ave. Duration
- 4h 44m
- When
- Every day
- Estimated price
- $65–400
Flights from Key West International Airport to Gainesville Regional Airport via Charlotte
- Ave. Duration
- 6h 40m
- When
- Every day
- Estimated price
- $110–550
Flights from Key West International Airport to Gainesville Regional Airport via Dallas/Ft.Worth
- Ave. Duration
- 8h 21m
- When
- Every day
- Estimated price
- $170–750
Flights from Key West International Airport to Orlando via Miami
- Ave. Duration
- 3h 23m
- When
- Every day
- Estimated price
- $50–340
Flights from Key West International Airport to Jacksonville via Miami
- Ave. Duration
- 3h 20m
- When
- Monday, Wednesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $90–600
Flights from Key West International Airport to Jacksonville via Charlotte
- Ave. Duration
- 5h 56m
- When
- Every day
- Estimated price
- $150–750
- Website
- delta.com
Flights from Key West International Airport to Gainesville Regional Airport via Atlanta
- Ave. Duration
- 5h 27m
- When
- Every day
- Estimated price
- $100–550
Flights from Key West International Airport to Jacksonville via Atlanta
- Ave. Duration
- 4h 48m
- When
- Every day
- Estimated price
- $130–700
- Website
- flybreeze.com
Flights from Key West International Airport to Orlando
- Ave. Duration
- 1h 20m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $50–170
- Phone
- +1 831-539-2901
- guestservices@gobrightline.com
- Website
- gobrightline.com
Train from Miami to Orlando
- Ave. Duration
- 3h 34m
- Frequency
- Every 3 hours
- Estimated price
- $15–230
- Book at
- https://www.gobrightline.com
- Smart
- $15–200
- Premium
- $65–230
- Phone
- +1 800-874-7245
- Tri-RailCustomerExperience@sfrta.fl.gov
- Website
- tri-rail.com
Train from Miami Airport Station to West Palm Beach Station
- Ave. Duration
- 1h 45m
- Frequency
- Hourly
- Estimated price
- $5–11
- Website
- https://www.tri-rail.com
- Weekend | Holiday
- $5
- Weekday
- $8–11
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Key West, FL to Miami, FL - International Airport
- Ave. Duration
- 4h
- Frequency
- 3 times a day
- Estimated price
- $170–200
- Website
- https://www.keysshuttle.com
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Miami Airport to Gainesville - Commuter Lot Parking Garage @ Gale Lemerand
- Ave. Duration
- 6h 35m
- Frequency
- 5 times a day
- Estimated price
- $26–140
- Website
- https://www.redcoachusa.com
- Web
- $26–140
Bus from Orlando RedCoach Station to Gainesville
- Ave. Duration
- 1h 55m
- Frequency
- Every 4 hours
- Estimated price
- $22–140
- Website
- https://www.redcoachusa.com
- Web
- $22–140
Bus from West Palm Beach, FL to Gainesville - Commuter Lot Parking Garage @ Gale Lemerand
- Ave. Duration
- 4h 56m
- Frequency
- 4 times a day
- Estimated price
- $25–140
- Website
- https://www.redcoachusa.com
- Web
- $25–140
Bus from University of South Florida Tampa to Gainesville - Commuter Lot Parking Garage @ Gale Lemerand
- Ave. Duration
- 2h 45m
- Frequency
- Once daily
- Estimated price
- $22–140
- Website
- https://www.redcoachusa.com
- Web
- $22–140
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Jacksonville to Gainesville
- Ave. Duration
- 1h 30m
- Frequency
- 6 times a week
- Estimated price
- $16–22
- Schedules at
- flixbus.com
Bus from Miami Airport Station to Gainesville
- Ave. Duration
- 6h 50m
- Frequency
- Twice daily
- Estimated price
- $45–70
- Schedules at
- flixbus.com
Bus from Fort Myers Bus Stop to University of South Florida
- Ave. Duration
- 3h 15m
- Frequency
- 3 times a day
- Estimated price
- $26–35
- Schedules at
- flixbus.com
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 53 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $22–29
- Website
- https://www.greyhound.com/
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Key West, FL to Fort Myers Beach, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
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