There are 5 ways to get from Key West to Fort Myers by ferry, bus (Greyhound, Flixbus), car, plane, or bus
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Ferry
best- Take the ferry from Key West, FL to Fort Myers Beach, FLferry Key West
4h 25m$160–175Bus
cheapest- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the bus from Miami Airport Station to Fort Myers Bus Stopbus
10h 2m$41–79Drive 274.3 mi
- Drive from Key West to Fort Myerscar 274.3 mi
5h 50m$51–73Fly to Tampa, bus
- Fly from Key West International Airport (EYW) to Tampa (TPA)plane EYW - TPA
- Take the bus from Tampa International Airport to Fort Myers 7-11bus
4h 50m$105–497Fly to Sarasota–Bradenton International Airport, bus
- Fly from Key West International Airport (EYW) to Sarasota–Bradenton International Airport (SRQ)plane EYW - SRQ
- Take the bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stopbus
7h 53m$392–1,232
Key West International Airport (EYW) to Tampa (TPA) flights
Questions & Answers
The cheapest way to get from Key West to Fort Myers is to bus which costs $40 - $80 and takes 10h 2m.
The fastest way to get from Key West to Fort Myers is to ferry which takes 4h 25m and costs $160 - $180.
No, there is no direct bus from Key West to Fort Myers. However, there are services departing from N Roosevelt & 3rd Street and arriving at Fort Myers Bus Stop via Big Pine Key and Miami Airport Station. The journey, including transfers, takes approximately 10h 2m.
The distance between Key West and Fort Myers is 154 miles. The road distance is 275.9 miles.
The best way to get from Key West to Fort Myers without a car is to ferry which takes 4h 25m and costs $160 - $180.
It takes approximately 4h 25m to get from Key West to Fort Myers, including transfers.
Key West to Fort Myers bus services, operated by Key West Transit, depart from N Roosevelt & 3rd Street station.
Key West to Fort Myers bus services, operated by Key West Transit, arrive at Big Pine Key - Auto Store / NAPA MM30 station.
Yes, the driving distance between Key West to Fort Myers is 276 miles. It takes approximately 5h 50m to drive from Key West to Fort Myers.
There are 3075+ hotels available in Fort Myers.
What companies run services between Key West, FL, USA and Fort Myers, FL, USA?
Key West Express operates a ferry from Key West, FL to Fort Myers Beach, FL once daily. Tickets cost $130 and the journey takes 4h. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Fort Myers Bus Stop via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, and Miami Airport Station in around 10h 2m.
- Website
- aa.com
Flights from Key West International Airport to Tampa via Miami
- Ave. Duration
- 3h 18m
- When
- Every day
- Estimated price
- $55–380
Flights from Key West International Airport to Sarasota–Bradenton International Airport via Miami
- Ave. Duration
- 4h 14m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $80–550
Flights from Key West International Airport to Sarasota–Bradenton International Airport via Charlotte
- Ave. Duration
- 5h 39m
- When
- Every day
- Estimated price
- $180–900
- Website
- flybreeze.com
Flights from Key West International Airport to Tampa
- Ave. Duration
- 1h 18m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $55–170
Flights from Key West International Airport to Sarasota–Bradenton International Airport via Raleigh/Durham
- Ave. Duration
- 5h 33m
- When
- Monday and Friday
- Estimated price
- $440–1,200
- Website
- delta.com
Flights from Key West International Airport to Sarasota–Bradenton International Airport via Atlanta
- Ave. Duration
- 5h 34m
- When
- Every day
- Estimated price
- $160–850
- Website
- spirit.com
Flights from Key West International Airport to Tampa via Fort Lauderdale
- Ave. Duration
- 3h 8m
- When
- Monday, Thursday, Friday, and Sunday
- Estimated price
- $100–380
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $21–40
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Miami Airport Station to Fort Myers Bus Stop
- Ave. Duration
- 3h 25m
- Frequency
- 4 times a day
- Estimated price
- $18–35
- Schedules at
- flixbus.com
Bus from Sarasota Cattlemen Transfer Center to Fort Myers Bus Stop
- Ave. Duration
- 1h 20m
- Frequency
- 4 times a day
- Estimated price
- $8–14
- Schedules at
- flixbus.com
- Phone
- +1 877 733 0724
- Website
- redcoachusa.com
Bus from Tampa International Airport to Fort Myers 7-11
- Ave. Duration
- 2h 10m
- Frequency
- 5 times a week
- Estimated price
- $23–140
- Website
- https://www.redcoachusa.com
- Web
- $23–140
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Key West, FL to Fort Myers Beach, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
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