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How to get fromKey West to Destinby plane, bus, taxi, car, or ferry

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There are 7 ways to get from Key West to Destin by plane, bus, taxi, car, or ferry

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Destin–Fort Walton Beach Airport

    best
    1. Fly from Key West International Airport (EYW) to Destin–Fort Walton Beach Airport (VPS)plane plane EYW - VPS
    4h 55m
    $112–399

  2. Bus, taxi via Sandy Springs

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta to Mobilebus bus
    5. Take the bus from Loxley to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    32h 8m
    $309–502

  3. Drive 745.9 mi

    1. Drive from Key West to Destincar car 745.9 mi
    14h 49m
    $137–197

  4. Fly to Pensacola International Airport, taxi

    1. Fly from Key West International Airport (EYW) to Pensacola International Airport (PNS)plane plane EYW - PNS
    2. Take the taxi from Pensacola-Airport-PNS to Destintaxi taxi
    5h 11m
    $432–774

  5. Fly to Northwest Florida Beaches International Airport, taxi

    1. Fly from Key West International Airport (EYW) to Northwest Florida Beaches International Airport (ECP)plane plane EYW - ECP
    2. Take the taxi from Northwest Florida Beaches International Airport (ECP) to Destintaxi taxi
    5h 33m
    $212–544

  6. Bus, taxi

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Tallahasseebus bus
    4. Take the bus from Tallahassee to Mobile Bus Stationbus bus
    5. Take the bus from Mobile to Crestviewbus bus
    6. Take the taxi from Crestview to Destintaxi taxi
    32h 42m
    $251–444

  7. Ferry, bus, drive, taxi

    1. Take the ferry from Key West, FL to Fort Myers Beach, FLferry ferry
    2. Take the bus from Fort Myers to Clewistonbus bus
    3. Drive from Clewiston to Port St Luciecar car
    4. Take the bus from Port St Lucie to Jacksonvillebus bus
    5. Take the bus from Jacksonville to Mobile Bus Stationbus bus
    6. Take the bus from Mobile to Crestviewbus bus
    7. Take the taxi from Crestview to Destintaxi taxi
    33h 23m
    $454–621

Key West International Airport (EYW) to Destin–Fort Walton Beach Airport (VPS) flights

Calendar44Weekly Planes
Duration5h 54mAverage Duration
Ticket$63Cheapest Price
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Questions & Answers

Map of how to get from Key West to Destin.ExpandLaunch map view
  • Distance: 523 mi
  • Duration: 4h 55m

What companies run services between Key West, FL, USA and Destin, FL, USA?

Allegiant Air, Delta, and American Airlines fly from Key West International Airport (EYW) to Destin–Fort Walton Beach Airport (VPS) every 4 hours.

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