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How to get fromKey West to Buffaloby plane, bus, train, bus (Greyhound, Flixbus), car, or shuttle

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There are 10 ways to get from Key West to Buffalo by plane, bus, train, bus (Greyhound, Flixbus), car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Key West International Airport (EYW) to Buffalo Niagara International Airport (BUF)plane plane EYW - BUF
    6h 26m
    $177–792

  2. Fly to Erie International Airport, bus

    cheapest
    1. Fly from Key West International Airport (EYW) to Erie International Airport (ERI)plane plane EYW - ERI
    2. Take the bus from Erie, PA to Buffalo, NYbus bus
    9h 11m
    $129–533

  3. Bus, train

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Amtrak Station to Newark Penn Stationtrain train
    4. Take the bus from Newark Penn Station to Buffalobus bus
    43h 1m
    $483–1,022

  4. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Washington Union Stationbus bus
    4. Take the bus from Washington Union Station to Pittsburgh Intermodal Stationbus bus
    5. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    43h 52m
    $245–554

  5. Drive 1,535.7 mi

    1. Drive from Key West to Buffalocar car 1,535.7 mi
    26h 32m
    $281–405

  6. Fly to Rochester, bus

    1. Fly from Key West International Airport (EYW) to Rochester (ROC)plane plane EYW - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    8h 8m
    $250–1,006

  7. Fly to Toronto Island Airport, train

    1. Fly from Key West International Airport (EYW) to Toronto Island Airport (YTZ)plane plane EYW - YTZ
    2. Take the train from Toronto Union Station to Buffalotrain train
    10h 33m
    $141–664

  8. Fly to Toronto Pearson International Airport, shuttle

    1. Fly from Key West International Airport (EYW) to Toronto Pearson International Airport (YYZ)plane plane EYW - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    8h 50m
    $207–622

  9. Bus, train via New York

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    44h
    $548–1,182

  10. Bus, train #2

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Amtrak Station to Pittsburgh Amtrak Stationtrain train
    4. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    2d 4h
    $523–1,252

Key West to Buffalo by bus, foot, taxi, and train

Calendar7Weekly Services
Duration43h 1mAverage Duration
Ticket$483Cheapest Price
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Questions & Answers

Map of how to get from Key West to Buffalo.ExpandLaunch map view
  • Distance: 1,293.4 mi
  • Duration: 6h 26m

What companies run services between Key West, FL, USA and Buffalo, NY, USA?

American Airlines, United Airlines, and Delta fly from Key West International Airport (EYW) to Buffalo Niagara International Airport (BUF) 5 times a day. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Buffalo, Ny via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Washington Union Station, and Pittsburgh, Pa in around 43h 52m.

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