There are 8 ways to get from Key West to Buffalo by plane, bus, train, car, or shuttle
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Buffalo Niagara International Airport
best- Fly from Key West International Airport (EYW) to Buffalo Niagara International Airport (BUF)plane EYW - BUF
6h 24m$377–1,842Fly to Erie International Airport, bus
cheapest- Fly from Key West International Airport (EYW) to Erie International Airport (ERI)plane EYW - ERI
- Take the bus from Erie, PA to Buffalo, NYbus
10h 43m$150–645Bus, train
- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the train from Miami Amtrak Station to Newark Penn Stationtrain
- Take the bus from Newark Penn Station to Buffalobus
42h 19m$386–887Drive 1,535.7 mi
- Drive from Key West to Buffalocar 1,535.7 mi
26h 32m$281–405Fly to Rochester, bus
- Fly from Key West International Airport (EYW) to Rochester (ROC)plane EYW - ROC
- Take the bus from Rochester Bus Stop to Buffalobus
7h 54m$248–1,158Fly to Toronto Pearson International Airport, shuttle
- Fly from Key West International Airport (EYW) to Toronto Pearson International Airport (YYZ)plane EYW - YYZ
- Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airport
9h 4m$347–582Bus, train via New York
- Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the train from Miami Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
- Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain
43h 38m$446–1,047Bus, train #2
- Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus Lks
- Take the bus from Big Pine Key to Miami Airport Stationbus
- Take the train from Miami Amtrak Station to Pittsburgh Amtrak Stationtrain
- Take the bus from Pittsburgh to Buffalobus
2d 4h$431–1,047
Key West International Airport (EYW) to Buffalo Niagara International Airport (BUF) flights
Questions & Answers
The cheapest way to get from Key West to Buffalo is to drive which costs $280 - $410 and takes 26h 32m.
The fastest way to get from Key West to Buffalo is to fly which takes 6h 24m and costs $370 - $1,900.
The distance between Key West and Buffalo is 1301 miles. The road distance is 1544.6 miles.
The best way to get from Key West to Buffalo without a car is to bus and train which takes 42h 19m and costs $380 - $900.
It takes approximately 6h 24m to get from Key West to Buffalo, including transfers.
Yes, the driving distance between Key West to Buffalo is 1545 miles. It takes approximately 26h 32m to drive from Key West to Buffalo.
There are 244+ hotels available in Buffalo.
What companies run services between Key West, FL, USA and Buffalo, NY, USA?
American Airlines and Delta fly from Key West International Airport (EYW) to Buffalo Niagara International Airport (BUF) every 4 hours.
- Website
- aa.com
Flights from Key West International Airport to Buffalo Niagara International Airport via Charlotte
- Ave. Duration
- 5h 43m
- When
- Every day
- Estimated price
- $360–1,800
Flights from Key West International Airport to Buffalo Niagara International Airport via Reagan Washington
- Ave. Duration
- 7h 50m
- When
- Every day
- Estimated price
- $360–1,800
Flights from Key West International Airport to Buffalo Niagara International Airport via Miami
- Ave. Duration
- 7h 30m
- When
- Saturday
- Estimated price
- $360–1,800
Flights from Key West International Airport to Rochester via Charlotte
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $210–1,100
Flights from Key West International Airport to Rochester via Reagan Washington
- Ave. Duration
- 6h 16m
- When
- Friday
- Estimated price
- $210–1,100
Flights from Key West International Airport to Rochester via Miami
- Ave. Duration
- 7h 27m
- When
- Saturday
- Estimated price
- $210–1,100
Flights from Key West International Airport to Toronto Pearson International Airport via Miami
- Ave. Duration
- 8h 3m
- When
- Every day
- Estimated price
- $110–550
Flights from Key West International Airport to Erie International Airport via Charlotte
- Ave. Duration
- 9h 40m
- When
- Every day
- Estimated price
- $120–600
Flights from Key West International Airport to Erie International Airport via Chicago O'Hare
- Ave. Duration
- 9h 46m
- When
- Every day
- Estimated price
- $150–700
- Website
- delta.com
Flights from Key West International Airport to Buffalo Niagara International Airport via Atlanta
- Ave. Duration
- 6h 41m
- When
- Every day
- Estimated price
- $370–1,800
Flights from Key West International Airport to Rochester via Atlanta
- Ave. Duration
- 5h 48m
- When
- Every day
- Estimated price
- $220–1,100
Flights from Key West International Airport to Toronto Pearson International Airport via Fort Lauderdale
- Ave. Duration
- 6h 40m
- When
- Tuesday
- Estimated price
- $160–1,000
Flights from Key West International Airport to Toronto Pearson International Airport via Tampa
- Ave. Duration
- 7h 26m
- When
- Monday and Friday
- Estimated price
- $160–1,000
- Website
- westjet.com
Flights from Key West International Airport to Buffalo Niagara International Airport via Atlanta
- Ave. Duration
- 5h 54m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $370–1,800
Flights from Key West International Airport to Rochester via Atlanta
- Ave. Duration
- 5h 35m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $220–1,100
Flights from Key West International Airport to Toronto Pearson International Airport via Fort Lauderdale
- Ave. Duration
- 6h 40m
- When
- Tuesday
- Estimated price
- $160–1,000
Flights from Key West International Airport to Toronto Pearson International Airport via Tampa
- Ave. Duration
- 7h 26m
- When
- Monday and Friday
- Estimated price
- $160–1,000
- Website
- aircanada.com
Flights from Key West International Airport to Toronto Pearson International Airport via Orlando
- Ave. Duration
- 6h 9m
- When
- Monday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $100–550
Flights from Key West International Airport to Toronto Pearson International Airport via Miami
- Ave. Duration
- 5h 35m
- When
- Friday
- Estimated price
- $110–550
Flights from Key West International Airport to Toronto Pearson International Airport via Raleigh/Durham
- Ave. Duration
- 6h 6m
- When
- Monday and Friday
- Estimated price
- $160–1,000
- Website
- flybreeze.com
Flights from Key West International Airport to Rochester via Raleigh/Durham
- Ave. Duration
- 6h 36m
- When
- Monday and Friday
- Estimated price
- $320–2,000
Flights from Key West International Airport to Erie International Airport via Orlando
- Ave. Duration
- 6h 34m
- When
- Wednesday
- Estimated price
- $190–1,200
- Website
- united.com
Flights from Key West International Airport to Toronto Pearson International Airport via Raleigh/Durham
- Ave. Duration
- 6h 6m
- When
- Monday and Friday
- Estimated price
- $160–1,000
Flights from Key West International Airport to Erie International Airport via Chicago O'Hare
- Ave. Duration
- 7h 50m
- When
- Monday
- Estimated price
- $150–700
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Miami Amtrak Station to Newark Penn Station
- Ave. Duration
- 26h 48m
- Frequency
- Once daily
- Estimated price
- $300–700
- Website
- https://www.amtrak.com/home.html
Train from Miami Amtrak Station to Ny Moynihan Train Hall At Penn Station
- Ave. Duration
- 27h 8m
- Frequency
- Once daily
- Estimated price
- $310–750
- Website
- https://www.amtrak.com/home.html
Train from Ny Moynihan Train Hall At Penn Station to Buffalo
- Ave. Duration
- 8h 45m
- Frequency
- 3 times a day
- Estimated price
- $95–230
- Website
- https://www.amtrak.com/home.html
Train from Miami Amtrak Station to Pittsburgh Amtrak Station
- Ave. Duration
- 36h 43m
- Frequency
- Once daily
- Estimated price
- $350–800
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 54 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30
- Ave. Duration
- 53 min
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Big Pine Key to Miami Airport Station
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $21–40
- Website
- https://www.greyhound.com/
Bus from Newark Penn Station to Buffalo
- Ave. Duration
- 8h 35m
- Frequency
- Once daily
- Estimated price
- $65–120
- Website
- https://www.greyhound.com/
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 25m
- Frequency
- 4 times a day
- Estimated price
- $11–22
- Website
- https://www.greyhound.com/
Bus from Erie, PA to Buffalo, NY
- Ave. Duration
- 1h 55m
- Frequency
- Once daily
- Estimated price
- $14–27
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Newark Penn Station to Buffalo
- Ave. Duration
- 7h 45m
- Frequency
- 5 times a day
- Estimated price
- $45–80
- Schedules at
- flixbus.com
Bus from Rochester Bus Stop to Buffalo
- Ave. Duration
- 1h 20m
- Frequency
- Every 3 hours
- Estimated price
- $8–15
- Schedules at
- flixbus.com
- Phone
- 905-374-8111
- airsales@niagaraairbus.com
- Website
- niagaraairbus.com
Shuttle from Pearson International Airport Terminal 1 to Buffalo Airport
- Ave. Duration
- 2h
- Frequency
- On demand
- Estimated price
- $90–120
- Website
- https://www.niagaraairbus.com
- Schedules at
- https://www.niagaraairbus.com
- Book at
- https://www.niagaraairbus.com
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Erie, PA to Buffalo, NY
- Ave. Duration
- 1h 35m
- Frequency
- Once daily
- Estimated price
- $8–45
- Website
- https://baronsbus.com
- Phone
- +1 814-574-1827
- Website
- fullingtontours.com
Bus from Pittsburgh to Buffalo
- Ave. Duration
- 7h 50m
- Frequency
- Once daily
- Estimated price
- $100–150
- Website
- https://www.fullingtontours.com
- Phone
- +1 800-858-8555
- Website
- trailways.com
Bus from Pittsburgh to Buffalo
- Ave. Duration
- 7h 50m
- Frequency
- Once daily
- Estimated price
- $40–180
- Website
- https://trailways.com
- Schedules at
- https://trailways.com/schedules/
- Saver
- $40–170
- Flexible
- $80–180
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