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How to get fromKey West to Buffaloby plane, bus, train, bus (Greyhound, Flixbus), or car

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There are 10 ways to get from Key West to Buffalo by plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Key West International Airport (EYW) to Buffalo Niagara International Airport (BUF)plane plane EYW - BUF
    6h 23m
    $177–842

  2. Fly to Toronto Island Airport, bus, train

    cheapest
    1. Fly from Key West International Airport (EYW) to Toronto Island Airport (YTZ)plane plane EYW - YTZ
    2. Take the bus from Union Stn Bus Terminal, 81 Bay St at Lakeshore Blvd, 2nd Floor to Bus Terminalbus bus
    3. Take the train from Niagara Falls Amtrak Station to Buffalotrain train
    9h 33m
    $125–709

  3. Bus, train

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Amtrak Station to Newark Penn Stationtrain train
    4. Take the bus from Newark Penn Station to Buffalobus bus
    43h 1m
    $852–1,372

  4. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Washington Union Stationbus bus
    4. Take the bus from Washington Union Station to Pittsburgh Intermodal Stationbus bus
    5. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    43h 37m
    $274–549

  5. Drive  1,535.7 mi

    1. Drive from Key West to Buffalocar car 1,535.7 mi
    26h 32m
    $281–405

  6. Fly to Rochester, bus

    1. Fly from Key West International Airport (EYW) to Rochester (ROC)plane plane EYW - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 51m
    $261–1,156

  7. Fly to Toronto Pearson International Airport, bus

    1. Fly from Key West International Airport (EYW) to Toronto Pearson International Airport (YYZ)plane plane EYW - YYZ
    2. Take the bus from Toronto Pearson Airport to Buffalobus bus
    9h 8m
    $127–527

  8. Fly to Erie International Airport, bus

    1. Fly from Key West International Airport (EYW) to Erie International Airport (ERI)plane plane EYW - ERI
    2. Take the bus from Erie to Buffalobus bus
    9h 19m
    $130–592

  9. Bus, train via New York

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    44h
    $1,032–1,642

  10. Bus, train #2

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Amtrak Station to Pittsburgh Amtrak Stationtrain train
    4. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    2d 4h
    $937–1,652

Key West to Buffalo by bus, foot, taxi, and train

Calendar7Weekly Services
Duration43h 1mAverage Duration
Ticket$852Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key West to Buffalo.ExpandLaunch map view
  • Distance: 1,293.4 mi
  • Duration: 6h 23m

What companies run services between Key West, FL, USA and Buffalo, NY, USA?

American Airlines, United Airlines, and Delta fly from Key West International Airport (EYW) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Buffalo, Ny via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Washington Union Station, and Pittsburgh, Pa in around 43h 37m.

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