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How to get fromKey West to Buffaloby plane, bus (Greyhound, Flixbus), bus, train, car, or shuttle

Find Transport to Buffalo

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There are 8 ways to get from Key West to Buffalo by plane, bus (Greyhound, Flixbus), bus, train, car, or shuttle

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Key West International Airport (EYW) to Buffalo Niagara International Airport (BUF)plane plane EYW - BUF
    6h 19m
    $234–1,043

  2. Fly to Niagara Falls International Airport

    cheapest
    1. Fly from Key West International Airport (EYW) to Niagara Falls International Airport (IAG)plane plane EYW - IAG
    20h 31m
    $116–468

  3. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    4. Take the bus from Atlanta Bus Station to Cleveland Bus Stationbus bus
    5. Take the bus from Cleveland Bus Station to Buffalobus bus
    43h 47m
    $260–524

  4. Bus, train

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    44h
    $589–1,247

  5. Drive 1,535.7 mi

    1. Drive from Key West to Buffalocar car 1,535.7 mi
    26h 33m
    $281–405

  6. Fly to Rochester, bus

    1. Fly from Key West International Airport (EYW) to Rochester (ROC)plane plane EYW - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 48m
    $190–757

  7. Fly to Toronto Pearson International Airport, shuttle

    1. Fly from Key West International Airport (EYW) to Toronto Pearson International Airport (YYZ)plane plane EYW - YYZ
    2. Take a shuttle bus from Pearson International Airport Terminal 1 to Buffalo Airportshuttle bus
    8h 30m
    $194–553

  8. Shuttle, train, bus

    1. Take a shuttle bus from Key West, FL to Miami, FL - International Airportshuttle bus
    2. Take the train from Miami Amtrak Station to Pittsburgh Amtrak Stationtrain train
    3. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    2d 3h
    $722–1,424

Key West to Buffalo by bus and foot

Calendar7Weekly Services
Duration43h 47mAverage Duration
Ticket$260Cheapest Price
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Questions & Answers

Map of how to get from Key West to Buffalo.ExpandLaunch map view
  • Distance: 1,297.7 mi
  • Duration: 6h 19m

What companies run services between Key West, FL, USA and Buffalo, NY, USA?

American Airlines, Delta, and United Airlines fly from Key West International Airport (EYW) to Buffalo Niagara International Airport (BUF) every 4 hours. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Buffalo via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, Atlanta Bus Station, and Cleveland Bus Station in around 43h 47m.

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