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How to get fromKey West to Buffaloby plane, bus (Greyhound, Flixbus), bus, train, or car

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There are 7 ways to get from Key West to Buffalo by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly to Buffalo Niagara International Airport

    best
    1. Fly from Key West International Airport (EYW) to Buffalo Niagara International Airport (BUF)plane plane EYW - BUF
    5h 58m
    $187–842

  2. Fly to Toronto Pearson International Airport, bus

    cheapest
    1. Fly from Key West International Airport (EYW) to Toronto Pearson International Airport (YYZ)plane plane EYW - YYZ
    2. Take the bus from Toronto Pearson Airport to Buffalobus bus
    9h 26m
    $128–498

  3. Bus

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the bus from Miami Airport Station to Newark Penn Stationbus bus
    4. Take the bus from Newark Penn Station to Buffalobus bus
    41h
    $300–469

  4. Bus, train via New York

    1. Take the bus from N Roosevelt & 4th Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    4. Take the train from Ny Moynihan Train Hall At Penn Station to Buffalotrain train
    44h
    $1,033–1,632

  5. Drive  1,535.7 mi

    1. Drive from Key West to Buffalocar car 1,535.7 mi
    26h 32m
    $263–380

  6. Fly to Rochester, bus

    1. Fly from Key West International Airport (EYW) to Rochester (ROC)plane plane EYW - ROC
    2. Take the bus from Rochester Bus Stop to Buffalobus bus
    7h 39m
    $262–1,156

  7. Bus, train

    1. Take the bus from N Roosevelt & 3rd Street to Big Pine Key - Auto Store / NAPA MM30bus bus Lks
    2. Take the bus from Big Pine Key to Miami Airport Stationbus bus
    3. Take the train from Miami Amtrak Station to Pittsburgh Amtrak Stationtrain train
    4. Take the bus from Pittsburgh, Pa to Buffalo, Nybus bus 510
    2d 4h
    $938–1,652

Key West to Buffalo by bus and foot

Calendar8Weekly Services
Duration41hAverage Duration
Ticket$300Cheapest Price
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Comparing Your Travel Options

Map of how to get from Key West to Buffalo.ExpandLaunch map view
  • Distance: 1,293.4 mi
  • Duration: 5h 58m

What companies run services between Key West, FL, USA and Buffalo, NY, USA?

United Airlines, Delta, and American Airlines fly from Key West International Airport (EYW) to Buffalo Niagara International Airport (BUF) 5 times a day. Alternatively, you can take a bus from N Roosevelt & 3rd Street to Buffalo via Big Pine Key - Auto Store / NAPA MM30, Big Pine Key, Miami Airport Station, and Newark Penn Station in around 41h.

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