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How to get fromKey West (Island) to San Diegoby plane, bus (Greyhound, Flixbus), bus, train or car

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There are 5 ways to get from Key West (Island) to San Diego by plane, bus (Greyhound, Flixbus), bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly

    best
    1. Fly from Key West International Airport (EYW) to San Diego International Airport (SAN)planeEYW - SAN
    8h 22m
    $210–900

  2. Bus

    1. Take the bus from Key West Airport to Miami Airport Stationbus
    2. Take the bus from Dolphin Mall - Miami to Houstonbus
    3. Take the bus from Houston to El Pasobus
    4. Take the bus from El Paso to 2474 E Florence Ave - Huntington Parkbus
    5. Take the bus from Huntington Park to San Diegobus
    2d 14h
    $480–862

  3. Bus, train

    1. Take the bus from Key West Airport to Miami Airport Stationbus
    2. Take the train from Hollywood Amtrak Station to Chicago Union Stationtrain
    3. Take the train from Chicago Union Station to Fullerton Amtrak Stationtrain
    4. Take the train from Fullerton Amtrak Station to San Diegotrain
    4d 3h
    $441–2,327

  4. Drive 2,783 mi

    1. Drive from Key West to San Diegocar2,783 mi
    45h 11m
    $508–734

  5. Bus via Atlanta

    1. Take the bus from Key West Airport to Miami Airport Stationbus
    2. Take the bus from Miami Airport Station to Atlanta Bus Stationbus
    3. Take the bus from Atlanta Bus Station to Dallas Bus Stationbus
    4. Take the bus from Dallas Bus Station to Los Angeles Union Stationbus
    5. Take the bus from Los Angeles Union Station to San Diegobus
    3d 1h
    $294–797

Key West (Island) to San Diego by bus and train

Calendar7Weekly Services
Duration4d 3hAverage Duration
Ticket$441Cheapest Price
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Questions & Answers

What companies run services between Key West (Island), FL, USA and San Diego, CA, USA?

United Airlines, Delta, and American Airlines fly from Key West International Airport (EYW) to San Diego International Airport (SAN) every 4 hours. Alternatively, you can take a bus from Key West Airport to San Diego via Miami Airport Station, Dolphin Mall - Miami, Houston, El Paso, and Huntington Park in around 2d 14h.

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