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How to get fromKey Largo to Sanibelby bus, taxi, car, shuttle, plane or bus (Greyhound, Flixbus)

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There are 6 ways to get from Key Largo to Sanibel by bus, taxi, car, shuttle, plane, or bus (Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Bus, taxi

    best
    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus
    2. Take the bus from Fort Lauderdale Airport to Naples, FLbus
    3. Take the taxi from Naples, FL to Sanibeltaxi
    6h 40m
    $126–209

  2. Drive 182.5 mi

    cheapest
    1. Drive from Key Largo to Sanibelcar182.5 mi
    3h 54m
    $34–49

  3. Shuttle, fly to Ft. Myers

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle
    2. Fly from Miami International Airport (MIA) to Ft. Myers (RSW)planeMIA - RSW
    6h 39m
    $191–517

  4. Bus via Pembroke Pines

    1. Take the bus from Key Largo Bus Stop to Miami Airport StationbusGreyhound US0720s
    2. Take the bus from Hollywood Sheridan Trirail Station to Fort Myers Bus StopbusFlixBus 2421
    7h 10m
    $81–119

  5. Bus

    1. Take the bus from Key Largo Bus Stop to Miami Airport StationbusGreyhound US0720s
    2. Take the bus from Miami Airport Station to Fort Myers Bus StopbusFlixBus 2421
    7h 55m
    $72–121

  6. Shuttle, fly to Tampa, bus, taxi

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle
    2. Fly from Miami International Airport (MIA) to Tampa (TPA)planeMIA - TPA
    3. Take the bus from Tampa International Airport to Fort Myers 7-11bus
    4. Take the taxi from Fort Myers 7-11 to Sanibeltaxi
    7h 16m
    $251–582

Miami International Airport (MIA) to Ft. Myers (RSW) flights

Calendar91Weekly Planes
Duration5h 14mAverage Duration
Ticket$55Cheapest Price
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Questions & Answers

What companies run services between Key Largo, FL, USA and Sanibel, FL, USA?

You can take a bus from Key Largo Bus Stop to Sanibel via Miami, Airport Intermodal Station, Miami Airport Station, Sheridan Street Station, Hollywood Sheridan Trirail Station, and Fort Myers Bus Stop in around 7h 10m.

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Need to know: Greyhound

Read the travel guideNeed to know: Greyhound

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