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How to get fromKey Largo to Myrtle Beachby shuttle, plane, bus, train or car

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There are 5 ways to get from Key Largo to Myrtle Beach by shuttle, plane, bus, train, or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Myrtle Beach

    best
    1. Take a shuttle bus from Key Largo, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Myrtle Beach (MYR)plane plane FLL - MYR
    4h 34m
    $188–709

  2. Drive 736.6 mi

    cheapest
    1. Drive from Key Largo to Myrtle Beachcar car 736.6 mi
    13h 3m
    $135–195

  3. Bus, train

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the train from Hollywood Amtrak Station to Charleston Amtrak Stationtrain train
    3. Take the bus from Charleston Bus Station to Myrtle Beach Bus Stationbus bus
    19h 54m
    $200–440

  4. Shuttle to Miami International Airport, fly to Myrtle Beach

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Myrtle Beach (MYR)plane plane MIA - MYR
    6h 45m
    $311–550

  5. Shuttle to Miami International Airport, fly to Wilmington International Airport, bus

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Wilmington International Airport (ILM)plane plane MIA - ILM
    3. Take the bus from Wilmington Cape Fear Public Transit to Myrtle Beach Bus Stationbus bus
    6h 59m
    $337–769

Key Largo to Myrtle Beach by bus and train

Calendar7Weekly Services
Duration19h 54mAverage Duration
Ticket$200Cheapest Price
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Questions & Answers

What companies run services between Key Largo, FL, USA and Myrtle Beach, SC, USA?

There is no direct connection from Key Largo to Myrtle Beach. However, you can take the shuttle to Fort Lauderdale, FL - International Airport, walk to Fort Lauderdale–Hollywood International Airport (FLL) airport, fly to Myrtle Beach (MYR), then take the taxi to Myrtle Beach. Alternatively, you can take a bus from Key Largo Bus Stop to Myrtle Beach Bus Station via Miami, Airport Intermodal Station, Miami Airport Station, Hollywood Station, Hollywood Amtrak Station, Charleston Amtrak Station, and Charleston Bus Station in around 19h 54m.

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