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How to get fromKey Largo to Knoxvilleby shuttle, plane, bus, train, bus (Greyhound, Flixbus) or car

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There are 10 ways to get from Key Largo to Knoxville by shuttle, plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Miami International Airport, fly to Mcghee Tyson Airport

    best
    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Mcghee Tyson Airport (TYS)plane plane MIA - TYS
    4h 47m
    $295–896

  2. Drive 901.5 mi

    cheapest
    1. Drive from Key Largo to Knoxvillecar car 901.5 mi
    15h 53m
    $165–238

  3. Bus, train via Farragut

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the train from Hollywood Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York to Knoxvillebus bus Nyc
    43h 56m
    $350–717

  4. Bus via Orlando

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Orlando Bus Stationbus bus
    3. Take the bus from Orlando Bus Station to New York City Chinatownbus bus
    4. Take the bus from New York City to Knoxvillebus bus Ny
    46h 30m
    $225–413

  5. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Mcghee Tyson Airport

    1. Take a shuttle bus from Key Largo, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Mcghee Tyson Airport (TYS)plane plane FLL - TYS
    5h 9m
    $282–815

  6. Bus to Key West International Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Key Largo Bus Stop to Key West Airportbus bus
    2. Fly from Key West International Airport (EYW) to Mcghee Tyson Airport (TYS)plane plane EYW - TYS
    6h 31m
    $265–1,194

  7. Shuttle to Miami International Airport, fly to Asheville Regional Airport, drive

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle bus
    2. Fly from Miami International Airport (MIA) to Asheville Regional Airport (AVL)plane plane MIA - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    6h 34m
    $187–491

  8. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Asheville Regional Airport, drive

    1. Take a shuttle bus from Key Largo, FL to Fort Lauderdale, FL - International Airportshuttle bus
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Asheville Regional Airport (AVL)plane plane FLL - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar car
    7h
    $194–450

  9. Bus, train

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the train from Hollywood Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain train
    3. Take the bus from New York City to Knoxvillebus bus Ny
    44h
    $290–622

  10. Bus

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus bus
    2. Take the bus from Miami Airport Station to Atlanta Bus Stationbus bus
    3. Take the bus from Atlanta Bus Station to New York City Chinatownbus bus
    4. Take the bus from New York City to Knoxvillebus bus Ny
    2d 3h
    $233–443

Key Largo to Knoxville by bus and foot

Calendar3Weekly Services
Duration46h 30mAverage Duration
Ticket$225Cheapest Price
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Questions & Answers

What companies run services between Key Largo, FL, USA and Knoxville, TN, USA?

You can take a bus from Key Largo Bus Stop to Knoxville Station Hall of Fame via Miami Airport Station, Orlando Bus Station, New York City, Knoxville, Walmart, and Charlie Haun WB Aft Washington PK in around 46h 30m.

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