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How to get fromKey Largo to Knoxvilleby shuttle, plane, bus, train, bus (Greyhound, Flixbus) or car

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There are 10 ways to get from Key Largo to Knoxville by shuttle, plane, bus, train, bus (Greyhound, Flixbus), or car

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Shuttle to Miami International Airport, fly to Mcghee Tyson Airport

    best
    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle
    2. Fly from Miami International Airport (MIA) to Mcghee Tyson Airport (TYS)planeMIA - TYS
    4h 47m
    $241–782

  2. Drive 901.5 mi

    cheapest
    1. Drive from Key Largo to Knoxvillecar901.5 mi
    15h 44m
    $165–238

  3. Bus, train via Farragut

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus
    2. Take the train from Hollywood Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
    3. Take the bus from New York to KnoxvillebusNyc
    43h 56m
    $381–982

  4. Bus via Orlando

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus
    2. Take the bus from Miami Airport Station to Orlando Bus Stationbus
    3. Take the bus from Orlando Bus Station to New York City Chinatownbus
    4. Take the bus from New York City to KnoxvillebusNy
    46h 32m
    $236–443

  5. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Mcghee Tyson Airport

    1. Take a shuttle bus from Key Largo, FL to Fort Lauderdale, FL - International Airportshuttle
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Mcghee Tyson Airport (TYS)planeFLL - TYS
    5h 4m
    $244–656

  6. Bus to Key West International Airport, fly to Mcghee Tyson Airport

    1. Take the bus from Key Largo Bus Stop to Key West Airportbus
    2. Fly from Key West International Airport (EYW) to Mcghee Tyson Airport (TYS)planeEYW - TYS
    6h 31m
    $216–852

  7. Shuttle to Miami International Airport, fly to Asheville Regional Airport, drive

    1. Take a shuttle bus from Key Largo, FL to Miami, FL - International Airportshuttle
    2. Fly from Miami International Airport (MIA) to Asheville Regional Airport (AVL)planeMIA - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar
    6h 41m
    $168–467

  8. Shuttle to Fort Lauderdale–Hollywood International Airport, fly to Asheville Regional Airport, drive

    1. Take a shuttle bus from Key Largo, FL to Fort Lauderdale, FL - International Airportshuttle
    2. Fly from Fort Lauderdale–Hollywood International Airport (FLL) to Asheville Regional Airport (AVL)planeFLL - AVL
    3. Drive from Asheville-Airport-AVL to Knoxvillecar
    6h 55m
    $171–431

  9. Bus, train

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus
    2. Take the train from Hollywood Amtrak Station to Ny Moynihan Train Hall At Penn Stationtrain
    3. Take the bus from New York City to KnoxvillebusNy
    44h
    $321–887

  10. Bus

    1. Take the bus from Key Largo Bus Stop to Miami Airport Stationbus
    2. Take the bus from Miami Airport Station to Atlanta Bus Stationbus
    3. Take the bus from Atlanta Bus Station to New York City Chinatownbus
    4. Take the bus from New York City to KnoxvillebusNy
    2d 3h
    $249–468

Key Largo to Knoxville by bus and foot

Calendar3Weekly Services
Duration46h 32mAverage Duration
Ticket$236Cheapest Price
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Questions & Answers

What companies run services between Key Largo, FL, USA and Knoxville, TN, USA?

You can take a bus from Key Largo Bus Stop to Knoxville Station Hall of Fame via Miami Airport Station, Orlando Bus Station, New York City, Knoxville, Walmart, and Charlie Haun WB Aft Washington PK in around 46h 32m.

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