There are 4 ways to get from Key Largo to Jacksonville by shuttle, plane, bus (Greyhound, Flixbus), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Shuttle, fly
best- Take a shuttle bus from Key Largo, FL to Miami, FL - International Airport
- Fly from Miami International Airport (MIA) to Jacksonville (JAX)MIA - JAX
5h 9m$287–525Bus
cheapest- Take the bus from Key Largo Bus Stop to Miami Airport StationGreyhound US0720s
- Take the bus from Miami Airport Station to JacksonvilleFlixBus 2431
11h 45m$60–122Bus, train
- Take the bus from Key Largo Bus Stop to Miami Airport Station
- Take the train from Miami Airport Station to Fort Lauderdale Station
- Take the train from Fort Lauderdale Amtrak Station to Jacksonville
12h 44m$65–341Drive 405.6 mi
- Drive from Key Largo to Jacksonville405.6 mi
6h 48m$74–107
Key Largo to Jacksonville by bus
Questions & Answers
The cheapest way to get from Key Largo to Jacksonville is to bus which costs $60 - $130 and takes 11h 45m.
The fastest way to get from Key Largo to Jacksonville is to shuttle and fly which takes 5h 9m and costs $280 - $550.
No, there is no direct bus from Key Largo to Jacksonville. However, there are services departing from Key Largo Bus Stop and arriving at Jacksonville via Miami Airport Station. The journey, including transfers, takes approximately 11h 45m.
The distance between Key Largo and Jacksonville is 414 miles. The road distance is 407.9 miles.
The best way to get from Key Largo to Jacksonville without a car is to bus which takes 11h 45m and costs $60 - $130.
It takes approximately 5h 9m to get from Key Largo to Jacksonville, including transfers.
Key Largo to Jacksonville bus services, operated by Greyhound USA, depart from Key Largo Bus Stop station.
Key Largo to Jacksonville bus services, operated by Greyhound USA, arrive at Miami Airport Station.
Yes, the driving distance between Key Largo to Jacksonville is 408 miles. It takes approximately 6h 48m to drive from Key Largo to Jacksonville.
Book your Key Largo to Jacksonville bus tickets online with Omio and FlixBus.
What companies run services between Key Largo, FL, USA and Jacksonville, FL, USA?
You can take a bus from Key Largo Bus Stop to Jacksonville via Miami Airport Station in around 11h 45m.
- Website
- aa.com
Flights from Miami International Airport to Jacksonville
- Ave. Duration
- 1h 29m
- When
- Every day
- Estimated price
- $55–370
- Phone
- +1 800-874-7245
- Website
- tri-rail.com
Train from Miami Airport Station to Fort Lauderdale Station
- Ave. Duration
- 46 min
- Frequency
- Hourly
- Estimated price
- $4–6
- Website
- https://www.tri-rail.com
- Weekend | Holiday
- $5
- Weekday
- $4–6
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Fort Lauderdale Amtrak Station to Jacksonville
- Ave. Duration
- 8h 1m
- Frequency
- Twice daily
- Estimated price
- $45–310
- Website
- https://www.amtrak.com/home.html
- Phone
- +1 (305) 289-9997
- groups@keysshuttle.com
- Website
- keysshuttle.com
Shuttle from Key Largo, FL to Miami, FL - International Airport
- Ave. Duration
- 1h 15m
- Frequency
- 4 times a day
- Estimated price
- $85–120
- Website
- https://www.keysshuttle.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Key Largo Bus Stop to Miami Airport Station
- Ave. Duration
- 1h 35m
- Frequency
- 3 times a day
- Estimated price
- $15–23
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Jacksonville
- Ave. Duration
- 9h 45m
- Frequency
- Once daily
- Estimated price
- $45–95
- Website
- https://www.greyhound.com/
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Miami Airport Station to Jacksonville
- Ave. Duration
- 9h 10m
- Frequency
- Twice daily
- Estimated price
- $45–100
- Schedules at
- flixbus.com
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