There are 4 ways to get from Kentucky to St. Louis by bus (Greyhound), car, or plane
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Bus
best- Take the bus from Louisville, KY to Evansville, INbus Louisville
- Take the bus from Evansville Bus Station to St Louis Bus Stationbus Greyhound US0185
6h 50m$73–121Drive 259.1 mi
cheapest- Drive from Louisville to St. Louiscar 259.1 mi
4h 16m$48–69Fly from Louisville International Airport
- Fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL)plane SDF - STL
5h 47m$105–706Fly from Covington
- Fly from Covington (CVG) to Lambert–St. Louis International Airport (STL)plane CVG - STL
5h 56m$154–954
Kentucky to St. Louis by bus
Questions & Answers
The cheapest way to get from Kentucky to St. Louis is to drive which costs $45 - $70 and takes 4h 16m.
The fastest way to get from Kentucky to St. Louis is to drive which takes 4h 16m and costs $45 - $70.
No, there is no direct bus from Kentucky to St. Louis station. However, there are services departing from Louisville, KY and arriving at St Louis Bus Station via Evansville Bus Station. The journey, including transfers, takes approximately 6h 50m.
The distance between Kentucky and St. Louis is 288 miles. The road distance is 260.6 miles.
The best way to get from Kentucky to St. Louis without a car is to bus which takes 6h 50m and costs $70 - $130.
It takes approximately 6h 50m to get from Kentucky to St. Louis, including transfers.
Kentucky to St. Louis bus services, operated by Miller Transportation, depart from Louisville, KY station.
The best way to get from Kentucky to St. Louis is to bus which takes 6h 50m and costs $70 - $130. Alternatively, you can fly, which costs $100 - $750 and takes 5h 47m.
Kentucky to St. Louis bus services, operated by Miller Transportation, arrive at Evansville, IN station.
St. Louis is 1h behind Kentucky. It is currently 11:34 PM in Kentucky and 10:34 PM in St. Louis.
What companies run services between Kentucky, USA and St. Louis, MO, USA?
You can take a bus from Louisville, KY to St Louis Bus Station via Evansville Bus Station in around 6h 50m. Alternatively, Southwest Airlines, United Airlines, and two other airlines fly from Louisville International Airport (SDF) to Lambert–St. Louis International Airport (STL) every 2 hours.
- Website
- delta.com
Flights from Louisville International Airport to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 5h 11m
- When
- Every day
- Estimated price
- $150–850
Flights from Louisville International Airport to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 6h 56m
- When
- Every day
- Estimated price
- $140–800
Flights from Covington to Lambert–St. Louis International Airport via Detroit
- Ave. Duration
- 4h 39m
- When
- Every day
- Estimated price
- $170–1,000
Flights from Covington to Lambert–St. Louis International Airport via Atlanta
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- $200–1,100
- Website
- united.com
Flights from Louisville International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 13m
- When
- Every day
- Estimated price
- $120–750
Flights from Covington to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 4h 28m
- When
- Every day
- Estimated price
- $150–950
- Website
- southwest.com
Flights from Louisville International Airport to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 3h 40m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $120–750
Flights from Louisville International Airport to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 4h 5m
- When
- Monday and Sunday
- Estimated price
- $100–700
Flights from Covington to Lambert–St. Louis International Airport via Chicago Midway
- Ave. Duration
- 3h 47m
- When
- Monday, Saturday, and Sunday
- Estimated price
- $150–950
Flights from Covington to Lambert–St. Louis International Airport via Nashville
- Ave. Duration
- 6h 10m
- When
- Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $150–950
- Website
- aa.com
Flights from Louisville International Airport to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 6h 6m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $120–750
Flights from Covington to Lambert–St. Louis International Airport via Chicago O'Hare
- Ave. Duration
- 5h 5m
- When
- Every day
- Estimated price
- $150–950
- Phone
- +1 502-368-5644 x 135
- Website
- ridewithmiller.com
Bus from Louisville, KY to Evansville, IN
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://ridewithmiller.com
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Evansville Bus Station to St Louis Bus Station
- Ave. Duration
- 3h 30m
- Frequency
- Once daily
- Estimated price
- $35–70
- Website
- https://www.greyhound.com/
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More Questions & Answers
Yes, the driving distance between Kentucky to St. Louis is 261 miles. It takes approximately 4h 16m to drive from Kentucky to St. Louis.
There are 353+ hotels available in St. Louis.





