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How to get fromKentucky to Iowaby plane, bus (Amtrak), bus, train, car or bus (Flixbus, Greyhound)

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There are 11 ways to get from Kentucky to Iowa by plane, bus (Amtrak), bus, train, car, or bus (Flixbus, Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Louisville International Airport to Quad City International Airport

    best
    1. Fly from Louisville International Airport (SDF) to Quad City International Airport (MLI)planeSDF - MLI
    6h 59m
    $74–425

  2. Bus

    1. Take the bus from Louisville, KY to Chicago Union Stationbus
    2. Take the bus from Chicago to Des MoinesbusChicago
    14h 19m
    $105–217

  3. Bus, train via Galesburg

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus
    2. Take the train from Indianapolis to Chicago Union Stationtrain
    3. Take the train from Chicago Union Station to Galesburg Amtrak Stationtrain
    4. Take the bus from Galesburg to Burlingtonbus
    5. Take the bus from Burlington to Des Moinesbus
    18h 11m
    $153–574

  4. Drive 580.9 mi

    1. Drive from Louisville to Des Moinescar580.9 mi
    9h 39m
    $106–154

  5. Fly Covington to Quad City International Airport

    1. Fly from Covington (CVG) to Quad City International Airport (MLI)planeCVG - MLI
    6h 43m
    $88–504

  6. Fly Covington to The Eastern Iowa Airport

    1. Fly from Covington (CVG) to The Eastern Iowa Airport (CID)planeCVG - CID
    7h 6m
    $112–592

  7. Bus to Nashville, fly to Des Moines

    1. Take the bus from Louisville, KY to Nashvillebus
    2. Fly from Nashville (BNA) to Des Moines (DSM)planeBNA - DSM
    6h 49m
    $162–719

  8. Bus to Nashville, fly to Omaha

    1. Take the bus from Louisville, KY to Nashvillebus
    2. Fly from Nashville (BNA) to Omaha (OMA)planeBNA - OMA
    7h 13m
    $170–728

  9. Fly Owensboro–Daviess County Regional Airport to Quad City International Airport

    1. Fly from Owensboro–Daviess County Regional Airport (OWB) to Quad City International Airport (MLI)planeOWB - MLI
    7h 1m
    $88–355

  10. Bus, train

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus
    2. Take the train from Indianapolis to Chicago Union Stationtrain
    3. Take the bus from Chicago to Des Moinesbus
    16h 39m
    $113–504

  11. Bus via Speedway

    1. Take the bus from El Mercadito Grocery - Clarksville, IN to Indianapolisbus
    2. Take the bus from Indianapolis to Chicago Bus Stationbus
    3. Take the bus from Chicago Bus Station to Des Moinesbus
    16h 40m
    $132–336

Kentucky to Iowa by bus and foot

Calendar14Weekly Services
Duration14h 19mAverage Duration
Ticket$105Cheapest Price
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Questions & Answers

What companies run services between Kentucky, USA and Iowa, USA?

United Airlines, Delta, and American Airlines fly from Louisville International Airport (SDF) to Quad City International Airport (MLI) every 2 hours. Alternatively, you can take a bus from Louisville, KY to Des Moines via Chicago Union Station and Chicago in around 14h 19m.

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