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How to get fromKentucky to Buffaloby plane, bus (Amtrak), bus, train, car, or bus (Amtrak, Greyhound, Flixbus)

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There are 9 ways to get from Kentucky to Buffalo by plane, bus (Amtrak), bus, train, car, or bus (Amtrak, Greyhound, Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Blue Grass Airport

    best
    1. Fly from Blue Grass Airport (LEX) to Buffalo Niagara International Airport (BUF)plane plane LEX - BUF
    5h 19m
    $131–615

  2. Bus via Cleveland

    cheapest
    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis to Toledobus bus
    3. Take the bus from Toledo to Clevelandbus bus
    4. Take the bus from Cleveland to Buffalobus bus
    14h 10m
    $73–214

  3. Bus, train (Amtrak)

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the train from Indianapolis to Chicago Union Stationtrain train
    3. Take the train from Chicago Union Station to Buffalo Depew Stationtrain train
    21h 4m
    $415–804

  4. Drive  531.4 mi

    1. Drive from Louisville to Buffalocar car 531.4 mi
    9h 2m
    $97–141

  5. Fly from Covington

    1. Fly from Covington (CVG) to Buffalo Niagara International Airport (BUF)plane plane CVG - BUF
    6h 23m
    $156–270

  6. Fly from Louisville International Airport

    1. Fly from Louisville International Airport (SDF) to Buffalo Niagara International Airport (BUF)plane plane SDF - BUF
    6h 29m
    $127–731

  7. Bus, train via Toledo

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis to Toledobus bus
    3. Take the train from Toledo to Buffalo Depew Stationtrain train
    14h 58m
    $206–499

  8. Bus, train via Toledo #2

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Toledo Bus Stopbus bus
    3. Take the train from Toledo to Buffalo Depew Stationtrain train
    15h 43m
    $222–358

  9. Bus

    1. Take the bus from Louisville, KY to Indianapolis Union Stationbus bus
    2. Take the bus from Indianapolis Union Station to Columbusbus bus
    3. Take the bus from Columbus to Buffalobus bus
    16h 4m
    $105–177

Kentucky to Buffalo by bus

Calendar7Weekly Buses
Duration14h 10mAverage Duration
Ticket$73Cheapest Price
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Comparing Your Travel Options

Map of how to get from Kentucky to Buffalo.ExpandLaunch map view
  • Distance: 476.4 mi
  • Duration: 5h 19m

What companies run services between Kentucky, USA and Buffalo, NY, USA?

Delta, United Airlines, and American Airlines fly from Blue Grass Airport (LEX) to Buffalo Niagara International Airport (BUF) hourly. Alternatively, you can take a bus from Louisville, KY to Buffalo via Indianapolis, Toledo, and Cleveland in around 14h 10m.

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